Longitudinal plasma proteomics of severe COVID-19

Investigating cellular pathways driving severe COVID-19: Fresh insights from longitudinal plasma proteomics

Speakers: Michael Filbin, M.D., M.Sc., Massachusetts General Hospital, Boston, MA, Arnav Mehta, M.D., Ph.D., Broad Institute of MIT and Harvard, Boston, MA

In this webinar you will:

  • Learn how the levels of over 600 plasma proteins differ between infected patients and controls, with a “viral response signature” of multiple cytokines and other proteins identified
  • Discover how more than 200 proteins also discriminate between severe and non-severe COVID-19, and how specific proteins are associated with survival or death in those with severe disease
  • Hear about the differential molecular and cellular immune responses to SARS-CoV-2 infection at the tissue and systemic level, and gain new insights into tissue-specific cell death signatures and cell-to-cell communication

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