“Proteogenomic strategies to advance drug development and precision medicine“
Speakers: Professor Ulf Gyllensten (Uppsala University) & Dr. Anders Mälarstig (Pfizer Sweden)
During the webinar, the speakers:
- Discussed how covariates (genetic, environmental, and clinical) can affect the levels of potential biomarkers
- Explored the use of covariate modeling to establish personally normalized plasma protein profiles (PNPPP) to reduce non-disease-related variation and maximize clinical potential
- Described how protein quantitative trait loci (pQTLs) can provide insights into disease biology and improve the efficiency of drug development
