del Campo M, Peeters C, Johnson E, et al. CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. (2022) Nature Aging, DOI: 10.1038/s43587-022-00300-1
In this study from Professor Charlotte Teunissen’s group in Amsterdam, diagnostic protein profiles for Alzheimer’s Disease (AD), previously identified in large-scale biomarker discovery studies using Olink technology, were verified and validated using an Olink® Focus custom-designed panel in independent cohorts. This verified that a 12-protein signature could discriminate AD from both healthy controls and non-AD dementia with high accuracy.