Group comparisons presented in a volcano plot
This provides fast and easy testing of a single hypothesis for all proteins analyzed in the study. The test can establish associations between protein levels and the variable of interest. Available tests include, but are not limited to T-tests, ANOVA and linear regressions.
Example of a volcano plot with significance on the y-axis and difference on the x-axis. The color indicates significance (multiple testing corrected p-value<0.05) and the line indicates raw p-value = 0.05. Top 10 proteins are labelled with protein names.