Olink publications - over 1400 and growing rapidly

Here you will find the latest list of publications that have used Olink’s panels for protein biomarker discovery in the reported studies, or which have reviewed our technology. The publications are grouped according to year of publication, and sorted alphabetically by first author. Links are provided to the journal abstract page or  PubMed entry for each publication, or where applicable, a link to the open-access full text version of the paper. While the large majority of articles citing the use of Olink come from human studies, those based on studies in non-human species are also highlighted below: Go to non-human studies list.

Tip: To search for keywords of interest within the publication titles below, type Ctrl+F and enter your search term.

Chronological list of publications

2023

Abozaid YJ, Ayada I, van Kleef LA,  et al. Plasma proteomic signature of fatty liver disease: the Rotterdam Study. (2023) Hepatology, DOI: 10.1097/HEP.0000000000000300
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Achten R, van Luijk C, Thijs J, et al. Non-Infectious Uveitis Secondary to Dupilumab Treatment in Atopic Dermatitis Patients Shows a Pro-Inflammatory Molecular Profile. (2023) Ocular Immunology and Inflammation, DOI: 10.1080/09273948.2023.2182325
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Aegisdottir HM, Thorolfsdottir RB, Sveinbjornsson G, et al. Genetic variants associated with syncope implicate neural and autonomic processes. (2023) European Heart Journal, DOI: 10.1093/eurheartj/ehad016
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Aguilera J, Kaushik A, Cauwenberghs N, et al. Granzymes, IL-16, and poly(ADP-ribose) polymerase 1 increase during wildfire smoke exposure. (2023) Journal of Allergy and Clinical Immunology: Global, DOI: 10.1016/j.jacig.2023.100093
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Ahmed A, Kania K, Abdul Rahim H, et al. Adrenomedullin peptides and precursor levels in relation to haemodynamics and prognosis after heart transplantation. (2023) ESC Heart Failure, DOI: 10.1002/ehf2.14399
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Ajie M, van Heck JIP, Janssen AWM, et al. Disease duration and chronic complications associate with immune activation in individuals with longstanding type 1 diabetes. (2023) Journal of Clinical Endocrinology and Metabolism, DOI: 10.1210/clinem/dgad087l
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Al-Janabi A, Martin P, Khan AR, et al. Integrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics. (2023) The Journal of Allergy and Clinical Immunology, DOI: 10.1016/j.jaci.2023.07.011
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Ali EA, Syed A, Khailova L, et al. Novel Biomarkers of Necrotizing Enterocolitis in Neonates Undergoing Congenital Heart Disease Surgery: A Pilot Cohort Study (2023) Journal of the American Heart Association, DOI: 10.1161/JAHA.123.030712
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Allan-Blitz LT, Akbari O, Kojima N, et al. Unique immune and inflammatory cytokine profiles may define long COVID syndrome. (2023) Clinical and Experimental Medicine, DOI: 10.1007/s10238-023-01065-6
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Allan-Blitz LT, Goodrich J, Hu H, et al. Altered Tumor Necrosis Factor Response in Neurologic Postacute SARS-CoV-2 Syndrome. (2023) Journal of Interferon & Cytokine Research, DOI: 10.1089/jir.2023.0051
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Allesøe RL, Lundgaard AT, Hernández Medina R, et al. Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models. (2023) Nature Biotechnology, DOI: 10.1038/s41587-022-01520-x
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Al-Sawaf O, Weiss J, Skrzypski M, et al. Body composition and lung cancer-associated cachexia in TRACERx. (2023) Nature Medicine, DOI: 10.1038/s41591-023-02232-8
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Álvez MB, Edfors F, von Feilitzen K, et al. Next generation pan-cancer blood proteome profiling using proximity extension assay. (2023) Nature Communications, DOI: 10.1038/s41467-023-39765-y
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Amodio D, Pascucci GR, Cotugno N, et al. Similarities and differences between myocarditis following COVID-19 mRNA vaccine and multiple inflammatory syndrome with cardiac involvement in children. (2023) Clinical Immunology, DOI: 10.1016/j.clim.2023.109751
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Andreasson U, Gobom J, Delatour V, et al. Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in blood. (2023) Clinical Chemistry and Laboratory Medicine, DOI: 10.1515/cclm-2022-1181
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Anker J, Pal SK, Kim-Schulze S, et al. Antitumor immunity as the basis for durable disease-free treatment-free survival in patients with metastatic urothelial cancer. (2023) Journal for Immunotherapy of Cancer, DOI: 10.1136/jitc-2023-007613
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Arias-de la Rosa I, Ruiz-Ponce M, Cuesta-López L, et al. Clinical features and immune mechanisms directly linked to the altered liver function in patients with rheumatoid arthritis. (2023) European journal of Internal Medicine, DOI: 10.1016/j.ejim.2023.08.002
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Arvidsson M, Ahmed A, Säleby J, et al. Plasma TRAIL and ANXA1 in diagnosis and prognostication of pulmonary arterial hypertension. (2023) Pulmonary Circulation, DOI: 10.1002/pul2.12269
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Bakhshi H, Michelhaugh SA, Bruce SA, et al. Association between proteomic biomarkers and myocardial fibrosis measured by MRI: the multi-ethnic study of atherosclerosis. (2023) EBioMedicine, DOI: 10.1016/j.ebiom.2023.104490
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Balzer MS, Pavkovic M, Frederick J, et al. Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution. (2023) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2023.100992
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Bao X-H, Chen B-F, Liu J, et al. Olink proteomics profiling platform reveals non-invasive inflammatory related protein biomarkers in autism spectrum disorder. (2023) Frontiers in Molecular Neuroscience, DOI: 10.3389/fnmol.2023.1185021
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Barak O, Lovelace T, Piekos S, et al. Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes. (2023) BMC Medicine, DOI: 10.1186/s12916-023-03054-8
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Barbarroja N, López-Montilla M, Cuesta-López L, et al. Characterization of the inflammatory proteome of synovial fluid from patients with psoriatic arthritis: Potential treatment targets. (2023) Frontiers in Immunology, DOI: 10.3389/fimmu.2023.1133435
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Batra R, Uni R, Akchurin OM, et al. Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. (2023) Molecular Medicine, DOI: 0.1186/s10020-023-00609-6
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Baumhove L, Bomer N, Tromp J, et al. Clinical characteristics and prognosis of patients with heart failure and high concentrations of interleukin-17D. (2023) International Journal of Cardiology, DOI: 10.1016/j.ijcard.2023.131384
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Bennett SJ, Davila CA, Reyes Z, et al. Immune profiling in Puerto Rican injection drug users with and without HIV-1 infection. (2023) Journal of Leukocyte Biology, DOI: 10.1093/jleuko/qiad045
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Bi W, Kraft A, Engelskircher S, et al. Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct-acting antivirals. (2023) European Journal of Immunology, DOI: 10.1002/eji.202250291
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Bidoki NH, Zera KA, Nassar H, et al. Machine learning models of plasma proteomic data predict mood in chronic stroke and tie it to aberrant peripheral immune responses. (2023) Brain, behavior, and Immunity, DOI: /10.1016/j.bbi.2023.08.002
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Biesemann N, Margerie D, Asbrand C, et al. Additive efficacy of a bispecific anti-TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis. (2023) Science Translational Medicine, DOI: 10.1126/scitranslmed.abq4419
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Björkander S, Klevebro S, Hernandez-Pacheco N, et al. Obese asthma phenotypes display distinct plasma biomarker profiles. (2023) Clinical & Translational Allergy, DOI: 10.1002/clt2.12238
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Blaauw M, Cristina dos Santos J, Vadaq N, et al.  Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size. (2023) iScience, DOI: 10.1016/j.isci.2023.106486
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Boberg E, Kadri N, Hagey DW, et al. Cognitive impairments correlate with increased central nervous system immune activation after allogeneic haematopoietic stem cell transplantation. (2023) Leukemia, DOI:  10.1038/s41375-023-01840-0
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Bouwens E, Vanmaele A, Hoeks SE, et al. Circulating biomarkers of cardiovascular disease are related to aneurysm volume in abdominal aortic aneurysm. (2023) Vascular Medicine, DOI: 10.1177/1358863X231181159
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Braadt L, Naumann M, Freuer D, et al. Novel inflammatory biomarkers associated with stroke severity: results from a cross-sectional stroke cohort study. (2023) Neurological Research and Practice, DOI: 10.1186/s42466-023-00259-3
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Bracco Gartner TCL, Wang Y, Leiteris L, et al. Cyclic strain has antifibrotic effects on the human cardiac fibroblast transcriptome in a human cardiac fibrosis-on-a-chip platform. (2023) Journal of the Mechanical Behavior of Biomedical Materials, DOI: 10.1016/j.jmbbm.2023.105980
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Brodeur KE, Liu M, Ibanez D, et al. Elevation of IL-17 cytokines distinguishes Kawasaki disease from other pediatric inflammatory disorders. (2023) Arthritis & Rheumatology, DOI: 10.1002/art.42680.
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Brown AA, Fernandez-Tajes JJ, Hong MG, et al. Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits. (2023) Nature Communications, DOI: 10.1038/s41467-023-40569-3
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Burman J, Zjukovskaja C, Svenningsson A, et al. Cerebrospinal fluid cytokines after autologous haematopoietic stem cell transplantation and intrathecal rituximab treatment for multiple sclerosis. (2023) Brain Communications, DOI: 10.1093/braincomms/fcad011
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Byappanahalli AM, Noren Hooten N, et al. Mitochondrial DNA and inflammatory proteins are higher in extracellular vesicles from frail individuals. (2023) Immunity and Ageing, DOI: 10.1186/s12979-023-00330-2
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Cai Y, Franceschini N, Surapaneni A, et al. Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait. (2023) Clinical Journal of the American Society of Nephrology, DOI: 10.2215/CJN.0000000000000257
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Calen C, Von Moos S, Cippá P, et al. Growth Differentiation Factor 15 and Risk of Death in Haemodialysis Patients. (2023) International Journal of Nephrology, DOI: 10.1155/2023/5163548
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Campbell K, Cawley NX, Luke R, et al. Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1. (2023) Biomarker Research, DOI: 10.1186/s40364-023-00448-x
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Cano A, Esteban-de-Antonio E, et al. Plasma extracellular vesicles reveal early molecular differences in amyloid positive patients with early-onset mild cognitive impairment. (2023) Nanobiotechnology, DOI: 10.1186/s12951-023-01793-7
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Cao L, Liu D, Karhunen V, et al. Circulating macrophage colony-stimulating factor levels and stroke: A Mendelian randomization study. (2023) Journal of Stroke and Cerebrovascular Diseases, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107050
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Cedeno-Veloz B, Lozano-Vicario L, Rodríguez-García A, et al. Serum biomarkers related to frailty predict negative outcomes in older adults with hip fracture. (2023) Journal of Endocrinological Investigation, DOI: 10.1007/s40618-023-02181-6
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Celik S, Sadrian J, Grossi M, et al. Extracellular Vesicle-Associated TWEAK Contributes to Vascular Inflammation and Remodeling During Acute Cellular Rejection. (2023) JACC: Basic to Translational Science, DOI: 10.1016/j.jacbts.2022.09.014
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Chen J, Doyle MF, Fang Y, et al. Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort. (2023) Aging Cell, DOI: 10.1111/acel.13955
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Chen QS, Bergman O, Ziegler L, et al. A machine learning based approach to identify carotid subclinical atherosclerosis endotypes. (2023) Cardiovascular Research, DOI: 10.1093/cvr/cvad106
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Chen Z, Soni N, Pinero G, et al. Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma. (2023) Nature Communications, DOI: 10.1038/s41467-023-37361-8
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Chitnis T, Foley J, Ionete C, et al. Clinical validation of a multi-protein, serum-based assay for disease activity assessments in multiple sclerosis. (2023) Clinical Immunology, DOI: 10.1016/j.clim.2023.109688
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Christensen TD, Madsen K, Maag E, et al. Protein Signatures and Individual Circulating Proteins, including IL-6 and IL-15, Associated with Prognosis in Patients with Biliary Tract Cancer. (2023) Cancers, DOI: 10.3390/cancers15041062
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Clavero E, Sanchez-Maldonado J, Macauda A, et al. Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization. (2023) International Journal of Molecular Sciences, DOI: 10.3390/ijms24108500
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Coral DE, Franks PW. Proteogenomic mapping sets stage for precision medicine. (2023) Nature metabolism, DOI: 10.1038/s42255-023-00759-1
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Cossins BC, van den Munckhof I, Rutten JHW, et al. Sex-specific association between adipose tissue inflammation and vascular and metabolic complications of obesity. (2023) The Journal of Clinical Endocrinology and Metabolism,  DOI: 10.1210/clinem/dgad193
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Davidsson P, Eketjäll S, Eriksson N, et al. VEGF-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease. (2023) Cardiovascular Research, DOI: 10.1093/cvr/cvad039
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Davies MPA, Sato T, Ashoor H, et al. Plasma protein biomarkers for early prediction of lung cancer. (2023) EBioMedicine, DOI: 10.1016/j.ebiom.2023.104686
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Dawrs SN, Virdi R, Islam MN, et al. Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model. (2023) Microbes and Infection, DOI: 10.1016/j.micinf.2023.105184
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Daza J, Salomé B, Okhawere KE, et al. Urine supernatant reveals a signature that predicts survival in clear cell renal cell carcinoma. (2023) BJU International, DOI: 10.1111/bju.15989
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Del Duca E, Renert-Yuval Y, Pavel AB, et al. Proteomic characterization of atopic dermatitis blood from infancy to adulthood. (2023) Journal of the American Academy of Dermatology, DOI: 10.1016/j.jaad.2022.12.050
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Deng J, Leijten E, Zhu Y, et al. Multi-omics Approach Identifies PI3 as a Biomarker for Disease Severity and Hyper-keratinization in Psoriasis. (2023) Journal of Dermatological Science, DOI: 10.1016/j.jdermsci.2023.07.005
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Diaz-Canestro C, Chen J, Liu Y, et al. A machine-learning algorithm integrating baseline serum proteomic signatures predicts exercise responsiveness in overweight males with prediabetes. (2023) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2023.100944
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Dimitsaki S, Gavriilidis GI, Dimitriadis VK and Natsiavas P, et al. Benchmarking of Machine Learning classifiers on plasma proteomic for COVID-19 severity prediction through interpretable artificial intelligence. (2023) Artificial Intelligence in Medicine, DOI: 10.1016/j.artmed.2023.102490
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Dobilas A, Åkesson A, Leandersson P, et al. A Multiplex Biomarker Assay Improves the Prediction of Survival in Epithelial Ovarian Cancer. (2023) Cancer Genomics & Proteomics, DOI: 10.21873/cgp.20380
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Dong H, Zhang L, Li B, et al. Screening inflammatory protein biomarkers on premature infants with necrotizing enterocolitis. (2023) Inflammation Research, DOI: 10.1007/s00011-023-01702-6
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Donnelly CG, Johnson AL, Reed S, et al. Cerebrospinal fluid and serum proteomic profiles accurately distinguish neuroaxonal dystrophy from cervical vertebral compressive myelopathy in horses. (2023) Journal of Veterinary Internal Medicine, DOI: 10.1111/jvim.16660
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Donovan K, Herrington W,  Guillaume P, et al. Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: A Mendelian Randomization Study. (2023) Clinical Journal of the American Society of Nephrology, DOI: 10.2215/CJN.05080422
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Drzeniek N, Kahwaji, N, Schlickeiser S, et al. Immuno-engineered mRNA combined with cell adhesive niche for synergistic modulation of the MSC secretome. (2023) Biomaterials, DOI: 10.1016/j.biomaterials.2022.121971
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Du Y, Khera T, Liu Z, et al. Controlled Attenuation Parameter Is Associated with a Distinct Systemic Inflammatory Milieu after Clearance of HCV Infection. (2023) Biomedicines, DOI: 10.3390/biomedicines11061529
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Duggan MR, Butler L, Peng Z, et al. Plasma proteins related to inflammatory diet predict future cognitive impairment. (2023) Molecular Psychiatry, DOI: 10.1038/s41380-023-01975-7
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Dulfer E, Geckin B, Taks E, et al. Timing and sequence of vaccination against COVID-19 and influenza (TACTIC): a single-blind, placebo-controlled randomized clinical trial. (2023) The Lancet Regional Health – Europe, DOI: 10.1016/j.lanepe.2023.100628
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Dunder L, Salihovic S, Monica Lind P, et al. Plasma levels of per- and polyfluoroalkyl substances (PFAS) are associated with altered levels of proteins previously linked to inflammation, metabolism and cardiovascular disease. (2023) Environment International, DOI: 10.1016/j.envint.2023.107979
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Duran-Castells C, Llano A, Kawana-Tachikawa A, et al. Sirtuin-2, NAD-Dependent Deacetylase, Is a New Potential Therapeutic Target for HIV-1 Infection and HIV-Related Neurological Dysfunction. (2023) Journal of Virology, DOI: 10.1128/jvi.01655-22
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Duran-Castells C, Prats A, Oriol-Tordera B, et al. Plasma proteomic profiling identifies CD33 as a marker of HIV control in natural infection and after therapeutic vaccination. (2023) EBioMedicine, DOI: 10.1016/j.ebiom.2023.104732
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Dyhrfort P, Svedung Wettervik T, Clausen F, et al. A Dedicated 21-Plex Proximity Extension Assay Panel for High-Sensitivity Protein Biomarker Detection Using Microdialysis in Severe Traumatic Brain Injury: The Next Step in Precision Medicine? (2023) Neurotrauma Reports, DOI: 10.1089/neur.2022.0067
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Edsfeldt A, Gonçalves I, Vigren I, et al. Circulating soluble IL-6 receptor associates with plaque inflammation but not with atherosclerosis severity and cardiovascular risk. (2023) Vascular Pharmacology, DOI: 10.1016/j.vph.2023.107214
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Edsfeldt A, Singh P, Matthes F, et al. Transforming growth factor-β2 is associated with atherosclerotic plaque stability and lower risk for cardiovascular events. (2023) Cardiovascular Research, DOI: 10.1093/cvr/cvad079
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Ehtewish H, Mesleh A, Ponirakis G, et al. Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia. (2023) International Journal of Molecular Sciences, DOI: 10.3390/ijms24098117
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Ekstrand J, Abrahamsson A, Lundberg P, et al. Breast density and estradiol are associated with distinct different expression patterns of metabolic proteins in normal human breast tissue in vivo. (2023) Frontiers in Oncology, DOI: 10.3389/fonc.2023.1128318
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El-Agnaf O, Bensmail I, Al-Nesf MAY, et al. Uncovering a neurological protein signature for severe COVID-19. (2023) Neurobiology of Disease, DOI: 10.1016/j.nbd.2023.10614710.1016/j.nbd.2023.106147
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Elfving A, Harila-Saari A, Nilsson L, et al. An explorative study on proteomic analyses related to inflammation and pain in children with juvenile idiopathic arthritis. (2023) BMC Pediatrics, DOI: 10.1186/s12887-023-04181-0
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Elrod J, Kiwit A, Lenz M, et al. Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox. (2023) Cells, DOI: 10.3390/cells12030366
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Eren F, Schwieler L, Orhan F, et al. Immunological protein profiling of first-episode psychosis patients identifies CSF and blood biomarkers correlating with disease severity. (2023) Brain, Behavior, and Immunity, DOI: 10.1016/j.bbi.2023.04.020
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Ernst MK, Evans ST, Techner JM,  et al. Vitamin D3 and deconvoluting a rash. (2023) JCI Insight, DOI: 10.1172/jci.insight.163789
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Espinosa C, Ali S, Khan W, et al. Comparative Predictive Power of Serum versus Plasma Proteomic Signatures in Feto-maternal Medicine. (2023) AJOG Global Reports, DOI: 10.1016/j.xagr.2023.100244
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Facheris P, Da Rosa JC, Pagan AD, et al. Age of onset defines two distinct profiles of atopic dermatitis in adults. (2023) Allergy, DOI: 10.1111/all.15741
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Feng X, Muller DC, Zahed H, et al. Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis. (2023) EBioMedicine, DOI: 10.1016/j.ebiom.2023.104623
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Feng X, Wu WY, Onwuka JU, et al. Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools. (2023) Journal of the National Cancer Institute, DOI: 10.1093/jnci/djad071
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Ferreira MB, Kobayashi M, Costa RQ, et al. Unsupervised clustering to differentiate rheumatoid arthritis patients based on proteomic signatures. (2023) Scandinavian Journal of Rheumatology, DOI: 10.1080/03009742.2023.2196781
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Freidin MB, Cheetham N, Duncan EL, et al. Long-COVID fatigue is not predicted by pre-pandemic plasma IL-6 levels in mild COVID-19. (2023) Inflammation Research, DOI: 10.1007/s00011-023-01722-2
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García-González P, de Rojas I, Moreno-Grau S, et al. Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer’s Disease Aetiopathogenesis in Men. (2023) International Journal of Molecular Sciences, DOI: 10.3390/ijms24020898
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Garishah FM, Boahen CK, Vadaq N, et al. Longitudinal proteomic profiling of the inflammatory response in dengue patients. (2023) PLOS Neglected Tropical Diseases, DOI: 10.1371/journal.pntd.0011041
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Gauthier S, Tran-Dinh A, Morilla I. Plasma proteome dynamics of COVID-19 severity learnt by a graph convolutional network of multi-scale topology. (2023) Life Science Alliance, DOI: 10.26508/lsa.202201624
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Geelen IGP, Gullaksen SE, Ilander MM, et al. Switching from imatinib to nilotinib plus pegylated interferon-α2b in chronic phase CML failing to achieve deep molecular response: clinical and immunological effects. (2023) Annals of Hematology, DOI: 10.1007/s00277-023-05199-1
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Gerhardt T, Seppelt C, Abdelwahed YS, et al. Culprit plaque morphology determines inflammatory risk and clinical outcomes in acute coronary syndrome. (2023) European Heart Journal, DOI: 10.1093/eurheartj/ehad334
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Ghorbani A, Avery LM, Sohaei D, et al. Discovery of novel glioma serum biomarkers by proximity extension assay. (2023) Clinical Proteomics, DOI: 10.1186/s12014-023-09400-5
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Girerd N, Levy D, Duarte K, et al. Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. (2023) Circulation Heart Failure, DOI: 10.1161/CIRCHEARTFAILURE.122.009694
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Guterstam Y, Acharya G, Schott K, et al. Immune cell profiling of vaginal blood from patients with early pregnancy bleeding. (2023) American Journal of Reproductive Immunology, DOI: 10.1111/aji.13738
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Ha CSR, Müller-Nurasyid M, Petrera A, et al. Proteomics biomarker discovery for individualized prevention of familial pancreatic cancer using statistical learning. (2023) PLoS One, DOI: 10.1371/journal.pone.0280399
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Hamadani M, Coleman M, Boccia R, et al. Safety and efficacy of parsaclisib in combination with obinutuzumab and bendamustine in patients with relapsed or refractory follicular lymphoma (CITADEL-102): A phase 1 study. (2023) Hematological Oncology, DOI: 10.1002/hon.3209
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Han J,  Correa da Rosa J, Agarwal A, et al. Modulation of Inflammatory Proteins in Serum May Reflect Cutaneous Immune Responses in Cancer Immunotherapy. (2023) JID Innovations, DOI: 10.1016/j.xjidi.2022.100179
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Hansson E, Broberg K, Wijkström J, et al. An explorative study of inflammation-related proteins associated with kidney injury in male heat-stressed workers. (2023) Journal of Thermal Biology, DOI: 10.1016/j.jtherbio.2022.103433
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Hartman E, Scott AM, Karlsson C, et al. Interpreting biologically informed neural networks for enhanced proteomic biomarker discovery and pathway analysis. (2023) Nature Communications, DOI: 10.1038/s41467-023-41146-4
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Hoefsmit EP, Völlmy F, Rozeman EA, et al. Systemic LRG1 Expression in Melanoma is Associated with Disease Progression and Recurrence. (2023) Cancer Research Communications, DOI: 10.1158/2767-9764.CRC-23-0015
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Hong DS, Van Tine BA, Biswas S,  et al. Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial. (2023) Nature Medicine, DOI: 10.1038/s41591-022-02128-z
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Houlder EL, Costain AH, Nambuya I, et al. Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis. (2023) Nature Communications, DOI: 10.1038/s41467-023-37502-z
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Huang J, Gill D, Zuber V, et al. Circulatory proteins relate cardiovascular disease to cognitive performance: A mendelian randomisation study. (2023) Frontiers in Genetics, DOI: 10.3389/fgene.2023.1124431
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Hüfner K, Vedova S, Tymoszuk P, et al. The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites. (2023) Psychoneuroendocrinology, DOI: /10.1016/j.psyneuen.2023.106334
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Huuhtanen J, Kasanen HH, Peltola K, et al. Single-cell characterization of anti-LAG3+anti-PD1 treatment in melanoma patients. (2023) Journal of Clinical Investigation, DOI: 10.1172/JCI164809
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Iakovliev A, McGurnaghan SJ, Hayward C, et al. Genome-wide aggregated trans-effects on risk of type 1 diabetes: A test of the “omnigenic” sparse effector hypothesis of complex trait genetics. (2023) American Journal of Human Genetics, DOI: 10.1016/j.ajhg.2023.04.003
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Iosef C, Knauer MJ, Nicholson M, et al. Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function. (2023) Journal of Translational Medicine, DOI: 10.1186/s12967-023-04149-9
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Jakimovski D, Qureshi F, Ramanathan M, et al. Proteomics and relationship with axonal pathology in multiple sclerosis: 5-year diffusion tensor imaging study. (2023) Brain Communications, DOI: 10.1093/braincomms/fcad183
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James CA, Baer JM, Zuo C, et al. Systemic Alterations in Type-2 Conventional Dendritic Cells Leads to Impaired Tumor Immunity in Pancreatic Cancer. (2023) Cancer Immunology Research, DOI: 10.1158/2326-6066.CIR-21-0946
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van den Berg V, Bouwens E, Umans V, de Maat M, Manintveld O, Caliskan K, Constantinescu A, Caliskan K, Constantinescu A, Mouthaan H, Cornel J-H, Baart S, Akkerhuis M, Boersma E and Kardys I. Longitudinally Measured Fibrinolysis Factors are Strong Predictors of Clinical Outcome in Patients with Chronic Heart Failure: The Bio-SHiFT Study. (2019) Thrombosis and Haemostasis, DOI: 10.1055/s-0039-1696973
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van der Wal H, Beverborg N, Dickstein K, Anker S, Lang C, Ng L, van Veldhuisen D, Voors A and van der Meer P. Iron deficiency in worsening heart failure is associated with reduced estimated protein intake, fluid retention, inflammation, and antiplatelet use. (2019) European Heart Journal, DOI: 10.1093/eurheartj/ehz680/5574384
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van der Zwan M, Hesselink D, Clahsen-van Groningen M and Baan C. Targeted proteomic analysis detects acute T cell-mediated kidney allograft rejection in belatacept-treated patients. (2019) Therapeutic Drug Monitoring, doi: 10.1097/FTD.0000000000000587
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Wang H, Davison M, Wang K, Xia T-H, Kramer M, Call K, Luo J, Wu X, Zuccarino R, Bacon C, Bai Y, Moran J, Gutmann L, Feely S, Grider T, Rossor A, Reilly M, Svaren J and Shy M. Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A. (2019) Annals of Clinical & Translational Neurology, DOI: 10.1002/acn3.50965
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Whelan C, Mattsson N, Nagle M, Vijayaraghavan S, Hyde C, Janelidze S, Stomrud E, Lee J, Fitz L, Samad T, Ramaswamy G, Margolin R, Mälarstig A and Hansson O. Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer’s disease. (2019) Acta Neuropathologica Communications, DOI: 10.1186/s40478-019-0795-2
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Wiberg A, Olsson-Strömberg U, Herman S, Kultima K and Burman J. Profound but Transient Changes in the Inflammatory Milieu of the Blood During Autologous Hematopoietic Stem Cell Transplantation. (2019) Biology of Blood and Marrow Transplantation, DOI: 10.1016/j.bbmt.2019.09.010
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Wierenga A, Cao J, Mouthaan H, van Weeghel C, Verdijk R, van Duinen S, Kroes W, Dogrusöz M, Marinkovic M, van der Burg S, Luyten G and Jager M. Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma. (2019) Investigative Ophthalmology & Visual Science, DOI: 10.1167/iovs.19-28309
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Wu P-H, Chiu Y-W, Zou H-B, Lee S-C, Lin Y-T, Tsai Y-T, Kuo M-C and Hwang S-J. Exploring the Benefit of 2-Methylbutyric Acid in Patients Undergoing Hemodialysis Using a Cardiovascular Proteomics Approach. (2019) Nutrition, DOI: 10.3390/nu11123033
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Zamaratskaia G, Omar NAM, Brunius C, Hallmans G, Johansson J-E, Andersson S-O, Larsson A, Åman P. and Landberg R. Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer. (2019) Clinical Nutrition, doi.org/10.1016/j.clnu.2019.01.007
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Zheng J, Maerz W, Gergei I et. al. Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures. (2019) Journal of Bone and Mineral Research, DOI: 10.1002/jbmr.3803
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Zhou H, Xi L, Ziemek D, O’Neil S, Lee J, Stewart Z, Zhan Y, Zhao S, Zhang Y, Page K, Huang A, Maciejewski M, Zhang B, Gorelick K, Fitz L, Pradhan V, Cataldi F, Vincent M, von Schack D, Hung K and Hassan-Zahraee M. Molecular Profiling of Ulcerative Colitis Subjects from the TURANDOT Trial Reveals Novel Pharmacodynamic/ Efficacy Biomarkers. (2019) Journal of Crohns and Colitis, doi.org/10.1093/ecco-jcc/jjy217
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Ziegler D, Strom A, Bönhof G, Kannenberg J, Heier M, Rathman W, Peters A, Meisinger C, Roden M, Thorand B and Herder C. Deficits in systemic biomarkers of neuroinflammation and growth factors promoting nerve regeneration in patients with type 2 diabetes and polyneuropathy. (2019) BMJ Open Diabetes Research & Care. DOI: 10.1136/bmjdrc-2019-000752
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2018

Abrahamsson A, Rzepecka A and Dabrosin C. Equal Pro-inflammatory Profiles of CCLs, CXCLs, and Matrix Metalloproteinases in the Extracellular Microenvironment In Vivo in Human Dense Breast Tissue and Breast Cancer. (2018) Frontiers in Immunology, doi: 10.3389/fimmu.2017.01994
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Al-Talabany S, Mordi I, Houston G, Colhoun H, Weir-McCall J, Matthew S, Looker H, Levin D, Belch J, Dove F, Khan F and Lang C. Epicardial adipose tissue is related to arterial stiffness and inflammation in patients with cardiovascular disease and type 2 diabetes. (2018) BMC Cardiovascular Disorders, doi.org/10.1186/s12872-018-0770-z
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Aqrawi L, Ivanchenko M, Björk A, Ramírez Sepúlveda J, Imgenberg-Kreuz J, Kvarnström M, Haselmayer P, Jensen J, Nordmark G, Chemin K, Skarstein G and Wahren-Herlenius M. Diminished CXCR5 expression in peripheral blood of patients with Sjögren’s syndrome may relate to both genotype and salivary gland homing. (2018) Clinical & Experimental  Immunology, doi: 10.1111/cei.13118
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Arrigo M, Vodovar N,Von Moos S, Masson E, Segerer S, Cippà P and Mebazaa A. High accuracy of proximity extension assay technology for the quantification of plasma brain natriuretic peptide. (2018) Journal of  Clinical Laboratory Analysis, doi.org/10.1002/jcla.22574
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Bao X, Borné Y, Faqir Muhammad I, Nilsson J, Lind L, Melander O, Niu K, Orho-Melander M and Engström G. Growth differentiation factor 15 is positively associated with incidence of diabetes mellitus: the Malmö Diet and Cancer–Cardiovascular Cohort (2018)  Diabetologia, DOI/10.1007/s00125-018-4751-7
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Barriuso J, Custodio A, Afonso R, Alonso V, Astudillo A, Capdevila J, Carbonero R, Grande E, Jimenez-Fonseca P, Marazuela M, Rodríguez-Antona C and Aller Y. Prognostic and predictive biomarkers for somatostatin analogs, peptide receptor radionuclide therapy and serotonin pathway targets in neuroendocrine tumours. (2018) Cancer Treatment Reviews, doi.org/10.1016/j.ctrv.2018.09.00
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Barwari T, Eminaga S, Mayr U, Lu R, Armstrong P, Chan M, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley S, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah A, Ghevaert C, Warner T, Fernández-Hernando C, Suárez Y and Mayr M. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. (2018) Journal of Clinical Investigation, doi.org/10.1172/jci.insight.123335.
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Berntsson J, Smith G, Johnson L, Söderholm M, Borné Y, Melander O, Orho-Melander M, Nilsson J and Engström G. Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke. (2018) Heart, doi:10.1136/heartjnl-2018-313684
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Bhandage A, Jin Z, Korol S, Shenb Q, Pe Y, Deng Q, Espes D, Carlsson P-O, Kamali-Moghaddamb M and Birnir B. GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.03.019
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Birgirsson H, Tsimogiannis K, Freyhult E and Kamali-Moghaddam M. Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer. (2018) Translational Oncology, doi:/10.1016/j.tranon.2018.05.012
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Borné Y, Gränsbo K, Nilsson J, Melander O, Orho-Melander M, Smith G and Engström G. Vascular Endothelial Growth Factor D, Pulmonary Congestion, and Incidence of Heart Failure. (2018) JACC, doi.org/10.1016/j.jacc.2017.11.058
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Bouzina H and Rådergran G. Low plasma stem cell factor combined with high transforming growth factor-α identifies high-risk patients in pulmonary arterial hypertension. (2018) ERJ Open Research, DOI: 10.1183/23120541.00035-2018.
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Brankovic M, Akkerhuis K, Mouthaan H, Brugts J, Manintveld O, van Ramshorst J, Germans T, Umans V, Boersma E and Kardys I. Cardiometabolic biomarkers and their temporal patterns predict poor outcome in chronic heart failure (Bio-SHiFT study). (2018) The Journal of Clinical Endocrinology & Metabolism, DOI: 10.1210/jc.2018-01241
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Brankovic M, Akkerhuis K, Mouthaan H, Constantinescu A, Caliskan K, van Ramshorst J, Germans T, Umans V and Kardys I. Utility of temporal profiles of new cardio-renal and pulmonary candidate biomarkers in chronic heart failure. (2018) International Journal of Cardiology, DOI: 10.1016/j.ijcard.2018.08.001
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Brodin P. The biology of the cell: insights from mass cytometry. (2018) The FEBS Journal, doi: 10.1111/febs.14693
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Bryl-Górecka P, Sathanoori R, Al-Mashat M, Olde B, Jögi J, Evander M, Laurell T and Erlinge D. Effect of exercise on the plasma vesicular proteome: a methodological study comparing acoustic trapping and centrifugation. (2018) Lab on a Chip, DOI: 10.1039/c8lc00686e
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Bränn E, Fransson E, White R, Papadopoulos F, Edvinsson Å, Kamali‐Moghaddam M, Cunningham J, Sundström‐Poromaa I and Skalkidou  A. Inflammatory markers in women with postpartum depressive symptoms (2018) Journal of Neuroscience Research, doi.org/10.1002/jnr.24312
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Buckley A, Lynam-Lennon N, Kennedy S, Dunne M, Aird J, Foley E, Clarke N, Ravi N, O’Toole D, Reynolds J, Kennedy B and O’Sullivan J. (2018) Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma. Oncotarget, Doi: 10.18632/oncotarget.25950
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Caja L,Tzavlaki K, Dadras M, Tan E-J, Hatem G, Maturi N, Morén A, Wik L, Watanabe Y, Savary K, Kamali-Moghaddan M, Uhrbom L, Heldin C-H and Moustakas A. Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells. (2018) Oncogene, doi:10.1038/s41388-018-0136-0
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Camargo MC, Sivins A, Isajevs S, Folkmanis V, Rudzite D, Gulley M, Offerhaus J, Leja M and Rabkin C. Associations of Epstein-Barr Virus-Positive Gastric Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response. (2018) Cancers, doi:10.3390/cancers10090284
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Cañadas-Garre M, Anderson K, McGoldrick J, Maxwell A and McKnight A. Proteomic and metabolomic approaches in the search for biomarkers in chronic kidney disease. (2018) Journal of Proteomics, doi:10.1016/j.jprot.2018.09.020
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Carlyle B, Trombetta B and Arnold S. Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias (2018) Proteomes, doi:10.3390/proteomes6030032
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Chowdhury R, Vallania F, Yang Q, Lopez Angel C, Darboe F, Penn-Nicholson A, Rozot V, Nemes E, Malherbe S, Ronacher K, Walzl G, Hanekom W, Davis M, Winter J, Chen X, Scriba T, Khatri P and Chien Y-H. A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes (2018) Nature, doi: 10.1038/s41586-018-0439-x
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Csösz E, Tóth N, Deák, E, Csutak A and Tözsér J. Wound-Healing Markers Revealed by Proximity Extension Assay in Tears of Patients following Glaucoma Surgery. (2018) Int. J. Mol. Sci, doi:10.3390/ijms19124096
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Defilippi C, Lo J, Christenson R, Grundberg I, Stone L, Zanni M, Lee H and Grinspoon S. Novel mediators of statin effects on plaque in HIV: a proteomics approach. (2018) AIDS, doi.org/10.1097/QAD.0000000000001762
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Dencker M, Arvidsson D, Karlsson M, Wollmer P, Andersen L and Thorsson O. Galectin-3 levels relate in children to total body fat, abdominal fat, body fat distribution, and cardiac size (2018) European J. Paediatrics, doi: 10.1007/s00431-017-3079-5
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Dencker M, Gårdinger Y, Björgell O and Hlebowicz J. Effect of food intake on biomarkers for cardiovascular disease and inflammation analyzed with the Proseek Multiplex CVD II kit. (2018) Genetics and Molecular Research, DOI: 10.4238/gmr16039884
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Di Pietro V, Porto E, Ragusa M, Barbagallo C, Davies D, Forcione M, Logan A, Di Pietro C, Purrello M, Grey M, Hammond D, Sawlani V, Barbey A and Belli A. Salivary microRNAs: diagnostic markers of mild traumatic brain injury in contact-sport. (2018) Frontiers in Molecular Neuroscience, doi.org/10.3389/fnmol.2018.00290
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Edvinsson Å, Bränn E,  Hellgren C, Freyhult E, White R, Kamali-Moghaddam M, Olivier J, Bergquist J, Boström A, Schiöth H, Skalkidou A, Cunningham J and Sundström-Poroma  I. Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction. (2018) Psychoneuroendocrinology, doi: 10.1016/j.psyneuen.2017.02.027
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Enblad G, Karlsson H, Gammelgård G, Wenthe J, Lövgren T, Amini M, Wikstrom K, Essand M, Savoldo B, Hallböök H, Höglund M, Dotti G, Brenner M, Hagberg H and Loskog A. A Phase I/IIa Trial Using CD19-Targeted ThirdGeneration CAR T Cells for Lymphoma and Leukemia. (2018) Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-18-0426
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Enroth S, Berggrund M, Lycke M, Lundberg M, Assarsson E, Olovsson M, Stålberg K, Sundfeldt K and Gyllensten U. A two-step strategy for identification of plasma protein biomarkers for endometrial and ovarian cancer. (2018) Clinical Proteomics, doi: 10.1186/s12014-018-9216-y
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Enroth S, Maturi, V, Berggrundi, M, Bosdotter Enroth S, Moustakas A, Johansson Å and Gyllensten U. Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases. (2018) Scientific Reports, DOI:10.1038/s41598-018-23860-y
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Feldreich T, Nowak C, Fall T, Carlsson A, Carrero J-J, Ripsweden J, Qureshi AR, Heimbürger O, Barany P, Stenvinke P, Vuilleumier N, Kalra P, Green D and Ärnlöv J. Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease. (2018) Journal of Nephrology, doi: 10.1007/s40620-018-0556-5
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Fernandez C, Rysä J, Almgren P, Nilsson J, Engström G, Orho‐Melander M, Ruskoaho H and Melander O. Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality. (2018) Journal of Internal Medicine, doi.org/10.1111/joim.12783
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Figarska S, Gustafsson S, Sundström J, Ärnlöv J, Mälarstig A, Elmståhl S, Fall T, Lind L and Ingelsson E. Associations of Circulating Protein Levels With Lipid Fractions in the General Population (2018) Arteriosclerosis, Thrombosis, and Vascular Biology, doi:/10.1161/ATVBAHA.118.311440
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Frändberg S, Asp J, Waldner B, Holgersson J and Palmqvist L. Concentration of the CDCP1 protein in human cord plasma may serve as a predictor of hematopoietic stem and progenitor cell content. (2018) Stem Cell Research, doi.org/10.1016/j.scr.2018.03.008
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Franzén B, Alexeyenko A, Kamali-Moghaddam M, Hatschek T, Kanter L, Ramqvist T, Kierkegaard G, Auer G, Landegren U and Lewensohn R. Protein profiling of fine needle aspirates reveals subtype‐associated immune signatures and involvement of chemokines in breast cancer. (2018) Molecular Oncology, doi.org/10.1002/1878-0261.12410
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Franzén B, Kamali‐Moghaddam M,  Alexeyenko A, Hatschek T, Becker S, Wik L, Kierkegaard J, Eriksson A, Reddy Muppani N, Auer G, Landegren U and Lewensohn R. A fine needle aspiration‐based protein signature discriminates benign from malignant breast lesions. (2018) Molecular Oncology, DOI: 10.1002/1878-0261.12350
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Gezelius E, Flou Kristensen A, Bendahl P, Hisada Y, Risom Kristensen S, Ek L, Bergman B, Wallberg M, Falkmer U, Mackman N, Pedersen S and Belting M. Coagulation biomarkers and prediction of venous thromboembolism and survival in small cell lung cancer: A sub-study of RASTEN – A randomized trial with low molecular weight heparin. (2018) PLOS ONE, doi: 10.1371/journal.pone.0207387
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Gupta V and Bernardini M. Algorithms Used in Ovarian Cancer Detection: A Minireview on Current and Future Applications (2018) Journal of Applied Laboratory Medicine, DOI: 10.1373/jalm.2017.025817
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Grufman H, Yndigegn T, Gonçalves I, Nilsson J and Schiopu A. Elevated IL-27 in patients with acute coronary syndrome is associated with adverse ventricular remodeling and increased risk of recurrent myocardial infarction and cardiovascular death (2018) Cytokine, doi.org/10.1016/j.cyto.2017.11.002
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Halak S, Östling G, Edsfeldt A, Kennbäck C, Dencker M, Gonçalves I and Asciutto G. Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms (2018) Cerebrovascular Diseases Extra, doi.org/10.1159/000485258
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Herder C, Kannenberg J, Carstensen-Kirberg M, Strom A, Bönhof G, Rathmann W, Huth C, Koenig W, Heier M, Krumsiek J, Peters A, Meisinger C, Roden M, Thorand B and Ziegler D. A Systemic Inflammatory Signature Reflecting Crosstalk Between Innate and Adaptive Immunity Is Associated With Incident Polyneuropathy: KORA F4/FF4 Study (2018) Diabetes, doi: 10.2337/db18-0060
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Holm Nielsen S, Tengryd C, Edsfeldt A, Brix S, Genovese F, Bengtsson E, Karsdal M, Leeming D, Nilsson J and Goncalves I. Markers of Basement Membrane Remodeling Are Associated With Higher Mortality in Patients With Known Atherosclerosis. (2018) Journal of the American Heart Association, DOI: 10.1161/JAHA.118.009193
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Johansson M, Ricci F, Aung N, Sutton R, Melander O and  Fedorowski A. Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension (2018) Hypertension, doi.org/10.1161/HYPERTENSIONAHA.117.10365
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Johansson M, Ricci F, Aung N, Sutton R, Melander O and  Fedorowski A. Inflammatory biomarker profiling in classical orthostatic hypotension: Insights from the SYSTEMA cohort (2018) Int. J. Cadiol., doi.org/10.1016/j.ijcard.2017.12.020
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Kasaian M, Lee J, Brennan A, Danto S, Black K, Fitz L and Dixon A. Proteomic analysis of serum and sputum analytes distinguishes controlled and poorly-controlled asthmatics. (2018) Journal of the British Society for Allergy and Clinical Immunology, doi.org/10.1111/cea.13151
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Kulasingam A, Hvas A-M, Lerkevang Grove E, Løkke Funck K and Dalby Kristensen S. Detection of biomarkers using a novel proximity extension assay in patients with ST-elevation myocardial infarction. (2018) Thrombosis Research, doi.org/10.1016/j.thromres.2018.10.011
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Kuschnerus K, Straessler E, Müller M, Lüscher T, Landmesser U and Kränkel N. Increased Expression of miR-483-3p Impairs the Vascular Response to Injury in Type 2 Diabetes. (2018) Diabetes, doi.org/10.2337/db18-0084
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Lagali N, Badian R, Liu X, Feldreich T, Ärnlöv J, Paaske Utheim T, Dahlin L and Rolandsson O. Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9. (2018) Scientific Reports, DOI:10.1038/s41598-018-32410-5
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Lagerstedt L, Egea-Guerrero J, Rodríguez-Rodríguez A, Bustamante A, Montaner J, El Rahal A, Andereggen R, Rinaldi L, Sarrafzadeh A, Schaller K and Sanchez J-C. Early measurement of interleukin-10 predicts the absence of CT scan lesions in mild traumatic brain injury. (2018) PLOS ONE, doi.org/10.1371/journal.pone.0193278
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Lampinen M, Vessby J, Fredricsson A, Wanders A, Rorsman F and Carlson M. High Serum sCD40 and a Distinct Colonic T Cell Profile in Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. (2018) Journal of Crohn’s and Colitis, doi.org/10.1093/ecco-jcc/jjy170
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Landegren U, Al-Amin R and Björkesten J. A myopic perspective on the future of protein diagnostics. (2018) New Biotechnology, doi.org/10.1016/j.nbt.2018.01.002
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Lareyre F, Moratal C, Chikande J, Jean-Baptiste E, Hassen-Khodja R, Neels J, Chinetti G and Raffort J. Investigation of Plasma Inflammatory Profile in Diabetic Patients With Abdominal Aortic Aneurysm: A Pilot Study (2018) Vascular and Endovascular Surgery, doi:/10.1177/1538574418784717
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Lendvai N, Tsakos I, Devlin S.,Schaffer W, Hassoun H, Lesokhin A, Landau H, Korde H, Mailankody S, Smith E, Chung D, Koehne G, Shah G, Alexander A, Patel M, Ballagi A, Grundberg I, Giralt S and Landgren O. Predictive biomarkers and practical considerations in the management of carfilzomib-associated cardiotoxicity (2018) Leukemia & Lymphoma, doi.org/10.1080/10428194.2017.1403020
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Lindgren K, Gülen Yaldir F, Hreinsson J, Holte J, Kårehed K, Sundström-Poromaa I, Kaihola H and Åkerud H. Differences in secretome in culture media when comparing blastocysts and arrested embryos using multiplex proximity assay. (2018) Upsala Journal of Medical Sciences, DOI:10.1080/03009734.2018.1490830
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Ljungberg J, Janiec M, Bergdah I, Holmgren A, Hultdin J, Johansson B, Näslund U, Siegbahn A, Fall T and Söderberg S. Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement. (2018) Circulation, doi.org/10.1161/CIRCULATIONAHA.117.030414
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Lovric A, Granér M, Bjornson E, Arif M, Benfeitas R, Nyman K, Ståhlman M, Pentikäinen M, Lundbom J, Hakkarainen A, Sirén R, Nieminen M, Lauerma K, Taskinen M-J, Mardinoglu A and Boren J. Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome. (2018) Scientific Reports, DOI:10.1038/s41598-018-31865-w
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Manor O, Zubair N, Conomos M, Xu X, Rohwer J, Krafft C, Lovejoy J and Magis A. A Multi-omic Association Study of Trimethylamine N-Oxide. (2018) Cell Reports, DOI: 10.1016/j.celrep.2018.06.096
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Mardinoglu A , Wu H , Bjornson E , Zhang  C, Hakkarainen A , Rasanen S , Lee S , Mancina R , Bergentall  M , Pietilainen K , Soderlund  S , Matikainen N , Stahlman M , Bergh, P-O , Adiels  M , Piening B, Graner M , Lundbom N , Williams K, Romeo S , Nielsen  J , Snyder M , Uhlen M , Bergstrom G , Perkins R , Marschall H-U , Backhed F , Taskinen M-R and Boren J. An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. (2018) Cell Metabolism, doi.org/10.1016/j.cmet.2018.01.005
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Memon A, Sundquist K,  PirouziFard M,  Elf J,  Strandberg K,  Svensson P,  Sundquist J and Zöller B. Identification of novel diagnostic biomarkers for deep venous thrombosis. (2018) British Journal of Haematology, doi.org/10.1111/bjh.15206
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Monaghan T, Mullish B, Patterson J, Wong G, Marchesi J, Xu H, Jilani T and Kao D. Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway. (2018) Gut Microbes, doi: 10.1080/19490976.2018.1506667
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Muhammad IF, Borné Y, Melander O, Orho-Melander M, Nilsson J, Söderholm M and Engström G. FADD (Fas-Associated Protein With Death Domain), Caspase-3, and Caspase-8 and Incidence of Ischemic Stroke (2018) Stroke, DOI: 10.1161/STROKEAHA.118.022063
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Natali A, Nesti L, Venturi E, Shore A, Khan F, Gooding K, Gates P, Looker H, Dove F, Goncalves I, Persson M and Nilsson J. Metformin is the key factor for elevated plasma GDF‐15 levels in type 2 diabetes: a nested, case‐control study. (2018) Diabetes, Obesity and Metabolism, doi.org/10.1111/dom.13519
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Nowak C, Carlsson A, Östgren CJ, Nyström F, Alam M, Feldreich T, Sundström J, Carrero J-J, Leppert J, Hedberg P, Henriksen E, Cordeiro A, Giedraitis V, Lind L, Inglesson E, Fall T and Ärnlöv J. Multiplex proteomics for prediction of major cardiovascular events in type 2 diabetes. (2018) Diabetologia, doi.org/10.1007/s0012
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Nuora A, Tupasela T, Jokioja J, Tahvonen R, Kallio H, Yanga B, Viitanen M and Linderborg K. The effect of heat treatments and homogenisation of cows’ milk on gastrointestinal symptoms, inflammation markers and postprandial lipid metabolism (2018) International Dairy Journal, doi.org/10.1016/j.idairyj.2018.05.017
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Olin A,  Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, Gustafsson A, Bernhardsson AK, Zhang C, Bohlin K and Brodin P. Stereotypic immune system development in newborn children. (2018) Cell, doi.org/10.1016/j.cell.2018.06.045.
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Qian J, Tikk K, Werner S, Balavarca Y, Saadat M, Hechtner M and Brenner H. Biomarker discovery study of inflammatory proteins for colorectal cancer early detection demonstrated importance of screening setting validation. (2018) Journal of Clinical Epidemiology, DOI: 10.1016/j.jclinepi.2018.07.016
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Tewari S, Renney G, Brewin J, Gardner K, Kirkham F, Inusa B, Barrett J, Menzel S, Thein S-L, Ward M and Rees D. Proteomic Analysis Of Plasma From Children With Sickle Cell Anemia And Silent Cerebral Infarction (2018) Haematolgica, Doi:10.3324/haematol.2018.187815
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Timotin A, Cinato M,Boal F, Dejean S, Anesia R, Arnaut O, Lagente C, Roncalli J, Desmoulin F, Tronchere H and Kunduzova O. Differential protein profiling as a potential multi-marker approach for obese patients with heart failure: A retrospective study. (2018) Scientific Reports, doi:, 10.1038/s41598-018-26118-9
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Toribio M, Fitch K, Stone L, Zanni M, Loa J, de Filippi C, Sponseller C, Lee H, Grundberg I, Thompson M, Aberg J and Grinspoon S. Assessing statin effects on cardiovascular pathways in HIV using a novel proteomics approach: Analysis of data from INTREPID, a randomized controlled trial. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.08.039
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Vossen A, van der Zee1 H, Davelaar N, Mus A, van Doorn M and Prens E. Apremilast for moderate hidradenitis suppurativa: no significant change in lesional skin inflammatory biomarkers. (2018) Journal of the European Academy of Dermatology and Venereology, doi.org/10.1111/jdv.15354
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Vroegindewey M, Oemrawsingh R, Kardys I, Asselbergs F, van der Harst P, Oude Ophuis A, Cramer G, Maas A, Hong Kie The S, Wardeh A, Mouthaan H, Boersma E and Akkerhuis M. The temporal pattern of immune and inflammatory proteins prior to a recurrent coronary event in post-acute coronary syndrome patients. (2018) Biomarkers, doi: 10.1080/1354750X.2018.1539768
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Wigren M, Svenugnsson E, Yao Mattisson I, Gustafsson J, Gunnarsson I, Zickert A, Elvin K, Jensen-Urstad K, Bengtsson A, Gullstrand B, Nordin Fredrikson G and Nilsson J. Cardiovascular disease in systemic lupus erythematosus is associated with increased levels of biomarkers reflecting receptor-activated apoptosis (2018) Atherosclerosis, doi: 10.1016/j.atherosclerosis.2018.01.022
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Yeung V, Webber J, Dunlop E, Morgan H, Hutton J, Gurney M, Jones E, Falcon-Perez J, Tabi Z, Errington R and Clayton A. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma (2018) Nanoscale, doi/10.1039/C8NR02417K
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Andersson E, Bergemalm D, Kruse R, Neumann G, D’Amato M, Repsilber D, and Halfvarson J. Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles. (2017) PLOS One, doi.org/10.1371/journal.pone.0186142
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Bergthorsdottir R, Ragnarsson O, Skrtic S, Glad K, Nilsson S, Louis Ross I, Leonsson-Zachrisson M and Johannsson G. Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients with Addison’s Disease; a case-control study (2017) The Journal of Clinical Endocrinology & Metabolism, doi.org/10.1210/jc.2017-01324
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Boldrup L,Troiano G,Gu X, Coates P,Fåhraeus R, Wilms T, Norberg-Spaak L, Wang L and Nylander K. Evidence that circulating proteins are more promising than miRNAs for identification of patients with squamous cell carcinoma of the tongue. (2017) Oncotarget, doi:10.18632/oncotarget.21402
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Boylan K, Geschwind K, Koopmeiners J, Geller M, Starr T and Skubitz A. A multiplex platform for the identification of ovarian cancer biomarkers (2017) Clinical Proteomics, DOI 10.1186/s12014-017-9169-6
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Brodin P & Davis M. Human immune system variation (2017), Nat. Rev. Immunol, 17, 21-29
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Bryan R, Gordon N, Abbotts B, Zeegers M, Cheng K, James N and  Ward D. Multiplex screening of 422 candidate serum biomarkers in bladder cancer patients identifies syndecan-1 and macrophage colony stimulating factor 1 as prognostic indicators. (2017) Translational Cancer Research, doi:10.21037/tcr.2017.04.19
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Bränn E, Papadopoulos F, Fransson E, White R, Edvinsson Å, Hellgren C, Kamali-Moghaddam M, Boström A, Schiöth H, Sundström-Poromaa H and Skalkidou A. Inflammatory markers in late pregnancy in association withpostpartum depression—A nested case-control study (2017) Psychoneuroendocrinology, doi.org/10.1016/j.psyneuen.2017.02.029
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Bäckryd E, Lind A-L, Thulin M,  Larsson A, Gerdle B and Gordh T. High levels of cerebrospinal fluid chemokines point to the presence of neuroinflammation in peripheral neuropathic pain: a cross-sectional study of 2 cohorts of patients compared with healthy controls. (2017) Pain, doi:10.1097/j.pain.0000000000001061
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Bäckryd E, Tanum L, Lind A-L, Larsson A and Gordh T. Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. (2017) Journal of Pain Research, https://doi.org/10.2147/JPR.S128508
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Carlsson A,Ingelsson E, Sundström J, Carrero J, Gustafsson S, Feldreich T, Stenemo M, Larsson A, Lind L and Ämlöv J. Use of Proteomics To Investigate Kidney Function Decline over 5 Years. Clinical Journal of the American Society of Nephrology (2017), doi: 10.2215/CJN.08780816
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Chen H, Qian J, Werner S, Cuk K, Knebel P and Brenner H. Development and validation of a panel of five proteins as blood biomarkers for early detection of colorectal cancer. (2017) Clinical Epidemiology, doi: 10.2147/CLEP.S144171
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Cornelis M,   Gustafsson S,  Ärnlöv J, Elmståhl S, Söderberg S,  Sundström J,   Michaëlsson K,  Lind L and Ingelsson E. Targeted proteomic analysis of habitual coffee consumption. (2017) Journal of Internal Medicine, doi.org/10.1111/joim.12703
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Cowley C, Owen A, Shiels S, Millar J,  Woolley R, Ives N, Osman H, Moss P and Bion J. Safety and Efficacy of Antiviral Therapy for Prevention of Cytomegalovirus Reactivation in Immunocompetent Critically Ill Patients.  (2017) JAMA Internal Medicine, doi:10.1001/jamainternmed.2017.0895
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deFilippi C and Seliger S. A Multibiomarker Approach to Heart Failure Prognostication : A Work in Progress (2017) JACC: Heart Failure, doi.org/10.1016/j.jchf.2017.02.019 [editorial]
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Eriksson E, Milenova I, Wenthe J, Stahle M, Leja-Jarblad J, Ullenhag G, Dimberg A, Moreno R, Alemany R and Loskog A. (2017) Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus. Clinical Cancer Research, Doi: 10.1158/1078-0432.CCR-17-0285
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Flintholm Raft K, Frestad D, Michelsen M, Suhrs H, Rask A, Nilsson M, Hermann T and Prescott E. Peripheral Endothelial Function and Coronary Flow Velocity Reserve Are Not Associated in Women with Angina and No Obstructive Coronary Artery Disease: The iPOWER Study (2017) Journal of Vascular Research, doi.org/10.1159/000479374
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Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge R, Frånberg M, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Enroth S, Johansson Å, Bosdotter Enroth S, Gustafsson S, Lind L, Lindgren C, Morris A, Giedraitis V, Silveira A, Franco-Cereceda A, Tremoli E, IMPROVE study group , Gyllensten U, Ingelsson E, Brunak S, Eriksson P, Ziemek D, Hamsten A and Mälarstig A. Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. (2017) PLOS Genetics 13(4), doi.org/10.1371/journal.pgen.1006706
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Gerdle B, Ghafouri B, Ghafouri N, Bäckryd E and Gordh T. Signs of ongoing inflammation in female patients with chronic widespread pain. A multivariate, explorative, cross-sectional study of blood samples. (2017) Medicine, http://dx.doi.org/10.1097/MD.0000000000006130
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Gohar A, Gonçalves I, Vrijenhoek J, Haitjema S, van Koeverden I, Nilsson J, de Borst G, de Vries J-P, Pasterkamp G, den Ruijter H, Björkbacka H and de Jager S. Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis (2017) International Journal of Cardiology, http://dx.doi.org/10.1016/j.ijcard.2017.03.101
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Hage C, Michaëlsson E, Linde C, Donal E, Daubert J-C, Gan L-M and Lund L. Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction. (2017) Circulation: Cardiovascular Genetics, doi.org/10.1161/CIRCGENETICS.116.001633
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Harlid S, Myte R and Van Guelpen B. The Metabolic Syndrome, Inflammation, and Colorectal Cancer Risk: An Evaluation of Large Panels of Plasma Protein Markers Using Repeated, Prediagnostic Samples. (2017) Mediators of Inflammation, doi:10.1155/2017/4803156
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Hill L, Di Pietro V, Hazeldine J, Davies D, Tomman E, Logan A and Belli A. Cystatin D (CST5): An ultraearly inflammatory biomarker of traumatic brain injury. (2017)  Scientific Reports, DOI:10.1038/s41598-017-04722-5
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Hofmann R, Tornvall P, Witt N, Alfredsson J, Svensson L, Jonasson L and Nilsson L. Supplemental oxygen therapy does not affect the systemic inflammatory response to acute myocardial infarction (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12716
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Jónsdóttir B, Jaworowski Å, San Miguel C and Melander O. IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation (2017) BMC Pulmonary Medicine, DOI: 10.1186/s12890-017-0377-7
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Kim J, Tomalin L, Lee J, Fitz L, Berstein G, Correa-da Rosa J, Garcet S, Lowes M, Valdez H, Wolk R, Suarez-Farinas M and Krueger J. Reduction of inflammatory and cardiovascular proteins in the blood of psoriasis patients; differential responses between tofacitinib and etanercept after 4 weeks of treatment. (2017) Journal of Investigative Dermatology, doi:10.1016/j.jid.2017.08.040A
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Kupcova Skalnikova H, Cizkova J, Cervenka J and Vodicka P. Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research (2017) Int. J. Mol. Sci., doi:10.3390/ijms18122697
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Lakshmikanth T, Olin A, Chen Y, Mikes J, Fredlund E, Remberger M, Omazic B and Brodin P. Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation (2017) Cell Reports, doi.org/10.1016/j.celrep.2017.08.021
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Langley S, Willeit K, Didangelos A, Perisic Matic L, Skroblin P, Barallobre-Barreiro J, Lengquist MN, Rungger G,Kapustin A, Kedenko L, Molenaar C, Lu R, Barwari T, Suna G, Yin X, Iglseder B,Paulweber B, Willeit P, Shalhoub J, Pasterkamp G,Davies A, Monaco C, Hedin U, Shanahan C, Willeit J, Kiechl S and Mayr M. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. (2017) Journal of  Clinical Investigation, doi:10.1172/JCI86924
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Larssen P, Wik L, Czarnewski P, Eldh M, Lof L, Ronquist J, Dubois L, Freyhult E, Gallant C, Oelrich J, Larsson A, Ronquist G, Villablanca E, Landegren U, Gabrielsson S and Kamali-Moghaddam M. Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay (2017) Molecular & Cellular Proteomics, doi: 10.1074/mcp.M116.064725
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Mahdessian H, Perisic Matic L, Lengquist M, Gertow K, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Tremoli E, Hamsten A, Eriksson P, Hedin U, Mälarstig A, IMPROVE study group. Integrative Studies Implicate Matrix Metalloproteinase 12 as a Culprit Gene for Large-Artery Atherosclerotic Stroke. (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12655
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Mazurkiewicz M, Hillert E-K, Wang X, Pellegrini P, Hägg Olofsson M, Selvaraju K, D’Arcy P and Linder S. Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition. (2017) Oncotarget, doi: 10.18632/oncotarget.15501
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Mohammad M, Noc N, Lang I, Holzer M, Clemmensen P, Jensen U, Metzler B and Erlinge, D. Proteomics in Hypothermia as Adjunctive Therapy in Patients with ST-Segment Elevation Myocardial Infarction: A CHILL-MI Substudy (2017) Therapeutic Hypothermia and Temperature Management, doi.org/10.1089/ther.2016.0041
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Molin C, Westerberg E and Rostedt Punga A. Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients (2017) Scientific Reports, doi:10.1038/srep39716.
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Mrazek F, Schneiderova P, Kriegova E, Raida L, Kuba A, Gajdos P, KönigovaJana N, Onderkova J and Ambruzova Z. Profile of Inflammation-Associated Proteins in Early Post-Transplant Samples of Patients After Allogeneic Hematopoietic Stem Cell Transplantation: a Preliminary Study. (2017) Archivum Immunologiae et Therapiae Experimentalis, DOI: 10.1007/s00005-016-0446-2.
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Panezai J, Ghaffar A, Altamash M, Sundqvist K-G, Engström P-E and Larsson A. Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. (2017) PLOS ONE, doi.org/10.1371/journal.pone.0188945
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Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum J, Alexander V, Willeit J, Kiech S and Mayr M. Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III (2017) Journal of the American College of Cardiology, Vol 69 (7) DOI: 10.1016/j.jacc.2016.11.065 (Online Appendix)
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Petrackova A, Smrzova A, Gajdos P, Schubertova M, Schneiderova P, Kromer P, Snasel V, Skacelova M, Mrazek F, Zadrazil J, Horak P and Kriegova E. Serum protein pattern associated with organ damage and lupus nephritis in systemic lupus erythematosus revealed by PEA immunoassay. (2017) Clinical Proteomics, DOI: 10.1186/s12014-017-9167-8
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Price N, Magis A, Earls J, Glusman G, Levy R, Lausted C, McDonald D, Kusebauch U, Moss C, Zhou Y, Qin S, Moritz R, Brogaard K, Omenn G, Lovejoy J and Hood L. A wellness study of 108 individuals using personal, dense, dynamic data clouds. (2017) Nature Biotechnology, doi:10.1038/nbt.3870
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Roerink M, Knoop H, Bronkhorst E, Mouthaan H, Luuk Hawinkels J, Joosten L and van der Meer J. Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment. (2017) Journal of Translational Medicine, doi: 10.1186/s12967-017-1371-9
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Savola P, Brück O, Olson T, Kelkka T, Kauppi M, Kovanen P, Kytölä S, Sokka-Isler T, Loughran T, Leirisalo-Repo M and Mustjoki S. Somatic STAT3 mutations in the Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia. (2017) Haematologica, doi:10.3324/haematol.2017.175729
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Schiza A, Wenthe J, Mangsbo S, Eriksson E, Nilsson A, Tötterman T, Loskog A and Ulenhag G. Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients. (2017) Journal of Translational Medicine, DOI: 10.1186/s12967-017-1182-z
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Schwenk J, Omenn G, Sun Z, Campbell D, Baker M, Overall C, Aebersold R, Moritz R and Deutsch E. The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays (2017) Journal of Proteome Research, doi:10.1021/acs.jproteome.7b00467
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Shen Q, Björkesten J, Galli J, Ekman D, Broberg J, Nordberg N, Tillander A, Kamali-Moghaddam M, Tybring G and Landegren U. Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays. (2017) Clinical Chemistry and Laboratory Medicine, doi: 10.1515/cclm-2017-0648
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Skau E, Henriksen E, Wagner P, Hedberg P, Siegbahn A and Leppert J. GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction (2017) European Journal of Preventive Cardiology, doi.org/10.1177/2047487317725017
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Smith G and Gerszten R. Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease (2017) Circulation, doi.org/10.1161/CIRCULATIONAHA.116.025446
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Solheim N, Östlund, S, Gordh T and Rosseland L.A. Women report higher pain intensity at a lower level of inflammation after knee surgery compared with men. (2017) Pain Reports, doi: 10.1097/PR9.0000000000000595
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Stenemo M, Nowak C, Byberg L, Sundström J, Giedraitis V, Lind L, Ingelsson E, Fall T and Ärnlöv J. Circulating proteins as predictors of incident heart failure in the elderly (2017) European Journal of Heart Failure, doi: 10.1002/ejhf.980
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Stensson N, Ghafouri B, Gerdle B and Ghafouri N. Alterations of anti-inflammatory lipids in plasma from women with chronic widespread pain – a case control study (2017) Lipids in Health &  Disease, DOI: 10.1186/s12944-017-0505-7
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Sukma Dewi I, Gidlöf O, Hollander Z, Lam K, Benson M, Braun O, Nilsson J, Tebbutt S, Ng R,  Öhman J, McManus B and Smith G. Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation. (2017) Journal of the American College of Cardiology, doi.org/10.1016/j.jacc.2017.10.012
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Uderhardt S, Ackermann J, Fillep T, Hammond V, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner K, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz‑Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins P, Schabbauer G, Mackman N, Voehringer D, Nadler J, Lee J, Massberg S, Rauh M, Kiechl S, Schett G, O’Donnell V and Krönke G. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. JEM (2017), doi.org/10.1084/jem.20161070
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Vallejo J,Dunér P, Fredrikson G, Nilsson J and Bengtsson E. Autoantibodies against aldehyde-modified collagen type IV are associated with risk of development of myocardial infarction. (2017) Journal of Internal Medicine, doi/10.1111/joim.12659/full
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Villani A-C, Satija1 R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager P, Rozenblatt-Rosen O, Lane A, Haniffa M, Regev A and Hacohen N. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. (2017) Science, DOI: 10.1126/science.aah4573
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West N, Corrigan J, Owen R, Hoole S, Brown A, Blatcher S and Newby, A. Percutaneous Sampling of Local Biomolecule Gradients Across Coronary Artery Atherosclerotic Plaques.(2017) JACC: Basic to Translational Science, doi: 10.1016/j.jacbts.2017.07.007
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Willeit K, Pechlaner R, Willeit P, Skroblin P, Paulweber B, Schernthaner C, Toell T, Egger G, Weger S, Oberhollenzer M, Kedenko L, Iglseder B, Bonora E, Schett G, Mayr M, Willeit J and Kiechl S. Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation. JAMA Cardiology (2017), doi:10.1001/jamacardio.2017.0064
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Yao Mattisson I, Björkbacka H, Wigren H, Edsfeldt A, Melander O, Nordin Fredrikson G, Bengtsson E, Gonçalves I, Orho-Melander M, Engström G, Almgren P and Nilsson J. Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease. (2017) EBioMedicine, doi.org/10.1016/j.ebiom.2017.11.023
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Yeh C, Adusumilli R, Kullolli M, Mallick P, John E and Pitteri S. Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer. (2017) Biomarker Research, DOI 10.1186/s40364-017-0110-y
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Zhang W, Ambikan A, Sperk M, van Domselaar R, Nowak P, Noyan K, Russom A,, Sönnerborg A and Neogi U. Transcriptomics and Targeted Proteomics Analysis to Gain  Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers. (2017) EBioMedicine, doi:10.1016/j.ebiom.2017.11.031
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Zwicker S, Lira-Junior R, Höög C, Almer S and Boström E. Systemic Chemokine Levels with “Gut-Specific” Vedolizumab in Patients with Inflammatory Bowel Disease—A Pilot Study (2017) International Journal of Molecular Sciences, doi: 10.3390/ijms18081827
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2016

Andreasson U, Blennow K and Zetterberg H. Update on ultrasensitive technologies to facilitate research on blood biomarkers for central nervous system disorders. Alzheimer’s & Dementia (2016), 3, 98-102.
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Berggrund M, Ekman D, Gustavsson I, Sundfeldt K, Olovsson M, Enroth S and Gyllensten U. Protein Detection Using the Multiplexed Proximity Extension Assay (PEA) from Plasma and Vaginal Fluid Applied to the Indicating FTA Elute Micro Card. J. Circ. Biomark. (2016), 5:9. doi:10.5772/64000
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Berntson L, Hedlund-Treutiger I and Alving K. Anti-inflammatory effect of exclusive enteral nutrition in patients with juvenile idiopathic arthritis. (2016) Clinical and Experimental Rheumatology, 34(5):941-945
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Carlsson A, Sundström J, Carrero J, Gustafsson S, Stenemo M, Larsson A, Lind L and Ärnlöv J. Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria. (2016) Eur J. Prev. Cardiol., DOI: 10.1177/2047487316676134.
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Chen H, Knebel P and Brenner H. Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer in screening settings to limit the number of false-positive findings. (2016) Journal Clinical Epidemiology, doi.org/10.1016/j.jclinepi.2016.01.022
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Darmanis S, Gallant C, Marinescu V,  Niklasson M, Segerman A,  Flamourakis G,  Fredriksson S, Assarsson E, Lundberg M, Nelander S, Westermark B and  Landegren U. Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells. (2016) Cell Reports 14, 380-389.
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Edsfeldt A, Bengtsson E, Asciutto G, Dunér P, Björkbacka H, Fredrikson G.N, Nilsson J, Goncalves I. High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy. Cerebrovasc Dis. (2016); 41:199-203
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Edfeldt K, Daskalakis K, Bäcklin C, Norlén O, Tiensuu Janson E, Westin G, Hellman P and Stålberg P. DcR3, TFF3 and Midkine are Novel Serum Biomarkers in Small Intestinal Neuroendocrine Tumors. (2016) Neuroendocrinology, DOI: 10.1159/000452891
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Eisenberg T. et. al. Cardioprotection and lifespan extension by the natural polyamine spermidine (2016) Nature Medicine, DOI: 10.1038/nm.4222.
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Enroth S, Hallmans G, Grankvist K and Gyllensten, U. (2016) Effects of long-term storage time and original sampling month on biobank plasma protein concentrations. EBioMedicine, 201608.038
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Genshaft A, Li S, Gallant C, Darmanis S, Prakadan S, Ziegler C, Lundberg M, Fredriksson S, Hong J, Regev A, Livak K, Landegren U and Shalek A. (2016) Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biology, 17:188 DOI 10.1186/s13059-016-1045-6
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Goncalves I, Edsfeldt A, Colhoun H, Shore A, Palombo C, Natali A, Nordin Fredrikson G, Björbacka H, Wigren M, Bengtsson E, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Gates P, Khan F, Looker H, Adams F, Belch J, Pinnola S, Venturi E, Kozakova M, Gan L, Schnecke C and Nilsson J. (2016) Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovascular Disorders, 16:171 DOI 10.1186/s12872-016-0346-8
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Gonçalves I, Hultman K, Dunér, P, Edsfeldt A, Hedblad B, Nordin Fredrikson G, Björkbacka H, Nilsson J and Bengtsson E. (2016) High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.  Open Heart.  3: doi:10.1136
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Grönberg C, Asciutto G, Persson A, Nordin Fredrikson G, Nilsson J, Gonçalves I and Björkbacka H. (2016) Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up. Cytokine, doi.org/10.1016/j.cyto.2016.06.009
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Huang B, Svensson P, Ärnlov J, Sundström J, Lind L and Ingelsson E. (2016) Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies. Atherosclerosis, 10.1016/j.atherosclerosis.2016.09.014
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Jahn L , Lee Hartline, Nagashree Rao, Brent Logan, Justin J Kim, Kevin Aylor , Li-Ming Gan, Helena U Westergren, and Eugene J Barrett. (2016) Insulin enhances endothelial function throughout the arterial tree in healthy but not metabolic syndrome subjects. J. Clin. Endocrinol. Metab.  doi: 10.1210/jc.2015-3293
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Kaihola H, Yaldir F, Hreinsson J, Hörnaeus K, Bergquist J, Olivier J, Åkerud H and Sundström-Poromaa I. (2016) Effects of Fluoxetine on Human Embryo Development. Frontiers in Cellular Neuroscience, doi: /10.3389/fncel.2016.00160
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Lind L, Sundström J, Stenmo M, Hagström E and Ärnlöv J. (2016) Discovery of new biomarkers for atrial fibrillation using a custom-made proteomics chip. Heart, 10.1136/heartjnl-2016-309764
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Loskog A, Maleka A, Mangsbo S, Svensson E, Lundberg C, Nilsson A, Krause J, Agnarsdottir M, Sundin A, Ahlström H, Tötterman T and Ullenhag G. (2016) Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients. British Journal of Cancer  114, 872–880. doi:10.1038/bjc.2016.42
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Lund N, Gränsbo, K, Wernersson C and Melander O. (2016) Cardiometabolic biomarkers are predictors of readmission and death in patients hospitalized for acute dyspnea  Am. J. Emergency Med., http://dx.doi.org/10.1016/j.ajem.2016.12.048
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Mailankody S, Devlin S, Korde N, Lendvai N, Lesokhin A, Landau H, Hassoun H, Ballagi A, Ekman D, Chung D, Patel M, Koehne G, Giralt S and Landgren O. (2016) Protein profiling in plasma cell disorders: a feasibility study. Leukemia & Lymphoma, DOI: 10.1080/10428194.2016.1258699
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Moen A, Lind A-L, Thulin M, Kamali-Moghaddam M, Røe C, Gjerstad J and Gordh T. (2016) Inflammatory serum protein profiling of patients with lumbar radicular pain one year after disc herniation. Int. J. Inflammation  Article ID 3874964.
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Schiopu A, Bengtsson E, Goncalves I, Nilsson J, Nordin Fredrikson G and Björbacka H. Associations Between Macrophage Colony-Stimulating Factor and Monocyte Chemotactic Protein 1 in Plasma and First-Time Coronary Events: A Nested Case–Control Study. (2016) J. Am Heart Assoc., 10.1161/JAHA.115.002851
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Schneiderova P, Pika T, Gajdos P, Fillerova R, Kromer P, Kudelka M, Minarik J, Papajik T, Scudla V and Kriegova E. Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma. (2016) Oncotarget.
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Shaw P, Yang Y, Gonzalez J, Kuruvilla S, Gottbrecht M, Epstein F,Gan L, Keeley E, Kramer C, Salerno M. Extracellular volume by CMR is associated with serum biomarkers of extracellular matrix turnover and inflammation in hypertensive heart disease. Journal of Cardiovascular Magnetic Resonance (2016)  doi:10.1186/1532-429X-18-S1-O103
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Söderlund S, Christiansson L, Persson I, Hjorth-Hansen H, Richter J, Simonsson B, Mustjoki S, Olsson-Strömberg U and Loskog A. Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli. (2016) Leukemia Research, DOI: 10.1016/j.leukres.2016.09.019
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Westergren H, Svedlund S, Momo R, Blomster J, Wåhlander K, Rehnström E, Greasley P, Regina Fritsche‑Danielson R, Oscarsson J and Gan L-M. Insulin resistance, endothelial function, angiogenic factors and clinical outcome in non‑diabetic patients with chest pain without myocardial perfusion defects. Cardiovasc Diabetol (2016) 15:36 DOI 10.1186
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Yang X, Tang Y, Alt, R, Xie, X and Lia, F. Emerging techniques for ultrasensitive protein analysis. Analyst (2016), 10.1039/C6AN00059B. (Review article).
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2015

Asciutto G, Dias NV, Edsfeldt A, Nitulescu M, Persson A, Nilsson M, Dunér P, Nilsson J, Gonçalves I. Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke. PLoS One. (2015) Mar 24;10(3):e0121086. doi: 10.1371/journal.pone.0121086.
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Chen H, Zucknick M, Werner S, Knebel P, Brenner H. Head-to-Head Comparison and Evaluation of 92 Plasma Protein Biomarkers for Early Detection of Colorectal Cancer in a True Screening Setting. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051. Epub 2015 May 26.
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Christiansson L, Söderlund S, Mangsbo S, Hjort-Hansen H, Höglund M, Markevärn B, Richter J, Stenke L, Mustjoki S, Loskog A, Olsson-Strömberg U. The tyrosine kinase inhibitors imatinib and dasatinib reduce myeloid suppressor cells and release effector lymphocyte responses. Mol Cancer Ther. (2015) May;14(5):1181-91. doi: 10.1158/1535-7163.MCT-14-0849.
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Enroth S, Bosdotter Enroth S, Johansson Å, Gyllensten U. Effect of genetic and environmental factors on protein biomarkers for common noncommunicable disease and use of personally normalized plasma protein profiles (PNPPP). Biomarkers. (2015) Sep;20(6-7):355-64. doi: 10.3109/1354750X.2015.1093546.
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Enroth S, Enroth SB, Johansson Å, Gyllensten U. Protein profiling reveals consequences of lifestyle choices on predicted biological aging. Sci Rep. (2015) Dec 1;5:17282. doi: 10.1038/srep17282
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Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Strain D, Kahn F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J. Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes. Arterioscler Thromb Vasc Biol. (2015) May 7. pii: ATVBAHA.115.305631.
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Greenwood C, Ruf D, Kirvell S, Johnson G, Dhillon HS, Bustin SA. Proximity assays for sensitive quantification of proteins. Biomol Det and Quantif. (2015). 4:10-16.
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Helseth R, Weiss T, Opstad T, Siegbahn A, Solheim S, Freynhofer M, Huber K, Arnesen H and Seljeflot S. Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction. Thrombosis Res. (2015), 136: 1240-1244
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Isgren A, Jakobsson J, Pålsson E, Ekman C J, Johansson A G.M., Sellgren C, Blennow K, Zetterberg H and Landén M. Increased cerebrospinal fluid interleukin-8 in bipolar disorder patients associated with lithium and antipsychotic treatment. Brain Behav Immun. (2015) Jan;43:198-204. doi: 10.1016/j.bbi.2014.10.001. Epub 2014 Oct 14.
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Kalla R, Kennedy NA, Hjelm F, Modig E, Sundell M, Söderholm J, Andreassen B, Bergemalm D, Ventham NT, Hjortswang H, Petr R, Vatn MH, Halfvarson J, Gullberg M, Satsangi J. OC-015 Proximity extension assay technology identifies novel serum biomarkers for predicting inflammatory bowel disease: IBD character consortium. Gut (2015);64:A8 doi:10.1136/gutjnl-2015-309861.15
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Kaudewitz D, Skroblin P, Bender LH, Barwari T, Willeit P, Pechlaner R, Sunderland NP, Willeit K, Morton A, Armstrong PC, Chan MV, Lu R, Yin X, Gracio F, Dudek K, Langley S, Zampetaki A, de Rinaldis E, Ye S, Warner TD, Saxena A, Kiechl S, Storey R, Mayr M. Association of MicroRNAs and YRNAs with Platelet Function. Circ Res. (2015) Feb 5;118(3):420-32. doi: 10.1161/CIRCRESAHA
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Larsson A, Carlsson L, Gordh T, Lind A-L, Thulin M, Kamali-Moghaddam M. The effects of age and gender on plasma levels of 63 cytokines. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051.
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Larsson A, Carlsson L, Lind A-L, Gordh T, Bodolea C, Kamali-Moghaddam M, Thulin M. The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid. Cytokine. (2015) Jul 15. pii: S1043-4666(15)30020-X. doi: 10.1016/j.cyto.2015.07.010.
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Lind L, Ärnlöv J, Lindahl B, Siegbahn A, Sundström J, Ingelsson E. Use of a proximity extension assay proteomics chip to discov