Olink® Signature Q100

A user-friendly benchtop system for protein biomarker analysis.

Run Olink kits easy and convenient in your own lab with Olink® Signature Q100, a dedicated solution for qPCR readout of Olink panels. With seamless integration between panel analysis to data output, you can simplify your research process with Olink® Target, Olink® Flex and Olink® Focus protein biomarker panels.

Key features & benefits

  • Developed specifically for Olink Target and Focus protein biomarker panels
  • Low investment threshold, broadening access to high quality protein biomarker analysis to more researchers than ever before
  • User-focused design with intuitive interface, including integrated software and IFC loader
  • Small, compact footprint
signature q100 video thumb

Olink® Signature Q100 is a desktop instrument that allows you to seamlessly utilize the Olink PEA protein analysis platform to get biological insights.

How does it work?

The unique technology behind the Olink platforms, Proximity Extension Assay (PEA) technology, is an innovative dual recognition, DNA-coupled methodology providing exceptional readout specificity. PEA enables high multiplex, rapid throughput biomarker analysis without compromising on data quality.

Antibody pairs labelled with DNA oligonucleotides bind target antigen in solution, allowing hybridization and extension by DNA polymerase. This newly created piece of DNA barcode is amplified by standard PCR before transfer to an integrated microfluidic chip (IFC), which is loaded into the instrument for qPCR and data readout.


Proximity Extension Assay (PEA) technology

Read more about how Olink technology delivers this scale of multiplexing and sample throughput without compromising on data quality or assay robustness.

Supported panels

Olink will continue to develop additional Target and custom panel offerings to further expand the utility of Olink Signature.

Olink® Target 96 & 48 panels for targeted protein biomarker discovery enable faster, better-informed decisions in human protein biomarker research by providing high-multiplex immunoassays that do not compromise on either data quality or performance.

Olink® Focus panels are available via custom projects with our R&D experts, and offer assays for up to 21 customer-selected proteins, with a choice of absolute or relative quantification.

Olink’s highly flexible made-to-order product, Olink® Flex, enables you to select and combine targets for up to 21 human proteins in one biomarker panel. Pick and choose from over 200 inflammation-related human proteins in a broad mix-and-match library.

Technical specifications

  • Memory: 16 GB
  • Storage: 1 TB HDD
  • Ports: 3 USB (1 in front, 2 in back) 1 GB/sec Ethernet
  • Power requirements: 100–240V; 8.0 A


  • Height: 55 cm (21.6 in)
  • Width: 27 cm (10.6 in)
  • Depth: 60 cm (23.6 in)/li>
  • Weight: 38 kg (83.6 lb)

Olink® NPX Signature is a data analysis software that is designed for the Olink Target analysis platform, including Olink Target 48, Olink Target 96, as well as for Olink Focus panels.

Keep your instruments up and running with Olink services and support. Olink Signature Q100 Service Agreements offer faster response times, proactive instrument care, and savings on repairs.

Are you prepared? To accommodate Olink Signature Q100, you need to assess and prepare the site so that installation can be performed and operation of the instrument will be successful.

Learn more about Signature Q100, the latest automated microfluidic PCR solution from Olink's development partner Fluidigm for use with Olink® Target and Olink® Focus panels.

A New Multiplex Protein Analysis Approach

Ordering or questions

Olink Signature Q 100 is now available for delivery. If you would like to place an order, or if you have any other questions regarding this product, please contact us using the form below.