• Olink® Target 96 Neurology Panels

    Thoroughly validated, high-performance protein biomarker panels available for Neurology studies.

    Olink® Target 96 panels specialize in key disease areas and important biological processes, and accelerate targeted protein biomarker research through high-multiplex immunoassays, providing uncompromised data quality and performance.

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    Key features & benefits

    • Allows for simultaneous analysis of 92 protein biomarkers
    • Uses only 1 µL of biological sample
    • Exceptional data quality through relative (NPX) quantification
    • qPCR readout with unparalleled sensitivity, specificity, and precision
    • All assays are subject to Olink’s strict technical validation and quality control procedures

    Olink Target 96 Neurology panels offer a broad selection of proteins associated with neurological functions and associated diseases. Categorization of the proteins included in the panel was carried out via referral to widely used public-access bioinformatic databases, including Uniprot, Human Protein Atlas, Gene Ontology (GO) and DisGeNET.

    Target

    Accelerate targeted protein biomarker research through high-multiplex immunoassays, providing uncompromised data quality and performance.
    Learn more about the Olink Target platform.

    Olink® Target 96 & 48

    How does it work?

    The unique technology behind the Olink platforms, Proximity Extension Assay (PEA) technology, is an innovative dual recognition, DNA-coupled methodology providing exceptional readout specificity. PEA enables high multiplex, rapid throughput biomarker analysis without compromising on data quality.

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    Read more about how Olink technology delivers this scale of multiplexing and sample throughput without compromising on data quality or assay robustness.

    Proximity Extension Assay (PEA) technology

    The Olink biomarker assay panels are available with the flexibility to best suit your needs. You can choose whether to purchase the panels as kits and run them in your own lab, or send your sample the experts at one of the many trained labs around the world offering sample analysis service.

    Panels

    Olink Target 96 Neuro Exploratory ( 92 )

    The assays in this panel includes a combination of exploratory and established markers with a focus on neurology-related diseases, and biological processes such as axon development, neurogenesis and synapse assembly. The established proteins include Neurofilament light polypeptide (Uniprot no. P07196)*, which is an important marker for degenerative neurological diseases and traumatic brain injury.

    The biomarker pages linked to below include calibrator curves that show the performance of each assay with the estimated sensitivity and dynamic range parameters indicated.

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    6-pyruvoyl tetrahydrobiopterin synthase (PTS)
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    Adhesion G protein-coupled receptor B3 (ADGRB3)
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    Alanyl-tRNA editing protein Aarsd1 (AARSD1)
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    Alpha-(1,6)-fucosyltransferase (FUT8)
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    Amiloride-sensitive amine oxidase [copper-containing] (AOC1)
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    Annexin A10 (ANXA10)
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    Asialoglycoprotein receptor 1 (ASGR1)
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    Beta-defensin 4A (DEFB4A_DEFB4B)
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    Beta-klotho (KLB)
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    Bis(5'-adenosyl)-triphosphatase (FHIT)
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    Bone marrow stromal antigen 2 (BST2)
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    C-C motif chemokine 27 (CCL27)
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    CD302 antigen (CD302)
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    CD63 antigen (CD63)
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    Cadherin-15 (CDH15)
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    Cadherin-17 (CDH17)
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    Calcineurin subunit B type 1 (PPP3R1)
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    Calcium-regulated heat-stable protein 1 (CARHSP1)
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    Calsyntenin-1 (CLSTN1)
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    Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3)
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    Cardiotrophin-1 (CTF1)
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    Centrin-2 (CETN2)
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    Ceramide transfer protein (CERT1)
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    Cysteine-rich protein 2 (CRIP2)
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    Death domain-containing protein CRADD (CRADD)
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    Desmoglein-3 (DSG3)
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    Dipeptidase 1 (DPEP1)
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    Dipeptidase 2 (DPEP2)
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    Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15)
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    Dual specificity protein phosphatase 3 (DUSP3)
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    E3 ubiquitin-protein ligase RNF31 (RNF31)
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    Endoplasmin (HSP90B1)
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    Endothelin-converting enzyme 1 (ECE1)
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    Ephrin type-A receptor 10 (EPHA10)
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    Eukaryotic translation initiation factor 4B (EIF4B)
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    Fibroblast growth factor receptor 2 (FGFR2)
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    Gamma-interferon-inducible lysosomal thiol reductase (IFI30)
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    Gamma-synuclein (SNCG)
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    Glutathione S-transferase P (GSTP1)
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    Glutathione hydrolase 5 proenzyme (GGT5)
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    Glycodelin (PAEP)
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    Group 10 secretory phospholipase A2 (PLA2G10)
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    Guanylate-binding protein 2 (GBP2)
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    Heme oxygenase 2 (HMOX2)
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    Immunoglobulin alpha Fc receptor (FCAR)
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    Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2)
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    Inhibitor of growth protein 1 (ING1)
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    Inositol monophosphatase 1 (IMPA1)
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    Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP)
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    Interferon lambda-1 (IFNL1)
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    Interleukin-15 (IL15)
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    Interleukin-3 receptor subunit alpha (IL3RA)
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    Interleukin-32 (IL32)
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    KIF-binding protein (KIFBP)
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    Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3)
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    Kin of IRRE-like protein 2 (KIRREL2)
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    Latent-transforming growth factor beta-binding protein 3 (LTBP3)
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    Leptin receptor (LEPR)
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    Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1)
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    Myeloid cell surface antigen CD33 (CD33)
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    N-alpha-acetyltransferase 10 (NAA10)
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    NEDD4-like E3 ubiquitin-protein ligase WWP2 (WWP2)
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    NEDD8-conjugating enzyme UBE2F (UBE2F)
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    Neurexophilin-1 (NXPH1)
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    Neurofilament light polypeptide (NEFL)
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    Nucleophosmin (NPM1)
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    Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5)
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    Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7)
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    Phosphoethanolamine/phosphocholine phosphatase (PHOSPHO1)
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    Phosphomevalonate kinase (PMVK)
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    Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1)
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    Prefoldin subunit 2 (PFDN2)
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    Pregnancy-specific beta-1-glycoprotein 1 (PSG1)
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    Proepiregulin (EREG)
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    Proline-rich AKT1 substrate 1 (AKT1S1)
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    Proteasome activator complex subunit 1 (PSME1)
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    Protein ABHD14B (ABHD14B)
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    Protein NDRG1 (NDRG1)
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    Ribokinase (RBKS)
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    Ribosomal protein S6 kinase beta-1 (RPS6KB1)
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    SPARC-related modular calcium-binding protein 1 (SMOC1)
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    Secreted frizzled-related protein 1 (SFRP1)
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    Signal recognition particle 14 kDa protein (SRP14)
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    Teratocarcinoma-derived growth factor 1 (TDGF1)
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    Transmembrane glycoprotein NMB (GPNMB)
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    Tubulin polymerization-promoting protein family member 3 (TPPP3)
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    Tubulin-folding cofactor B (TBCB)
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    Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C)
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    Tyrosine-protein phosphatase non-receptor type 1 (PTPN1)
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    V-set and transmembrane domain-containing protein 1 (VSTM1)
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    V-type proton ATPase subunit F (ATP6V1F)
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    Zinc finger protein Helios (IKZF2)
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    Olink Target 96 Neurology ( 92 )

    The assays in this panel offers a mix of established markers related to neurobiological processes and neurological diseases (e.g. neural development, axon guidance, synaptic function, or specific conditions such as Alzheimer’s disease), as well as some more exploratory proteins with broader roles in processes such as cellular regulation, immunology, development and metabolism. Of the 92 assays provided, 89 are unique to this panel.

    The biomarker pages linked to below include calibrator curves that show the performance of each assay with the estimated sensitivity and dynamic range parameters indicated.

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    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38)
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    Alpha-2-macroglobulin receptor-associated protein (LRPAP1)
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    BDNF/NT-3 growth factors receptor (NTRK2)
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    Beta-nerve growth factor (NGF)
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    Bone morphogenetic protein 4 (BMP4)
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    Brevican core protein (BCAN)
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    Brorin (VWC2)
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    C-type lectin domain family 1 member B (CLEC1B)
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    C-type lectin domain family 10 member A (CLEC10A)
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    CMRF35-like molecule 1 (CD300LF)
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    CMRF35-like molecule 6 (CD300C)
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    Cadherin-3 (CDH3)
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    Cadherin-6 (CDH6)
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    Carboxypeptidase A2 (CPA2)
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    Carboxypeptidase M (CPM)
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    Cathepsin S (CTSS)
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    Cell adhesion molecule 3 (CADM3)
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    Cell surface glycoprotein CD200 receptor 1 (CD200R1)
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    Contactin-5 (CNTN5)
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    Cytotoxic and regulatory T-cell molecule (CRTAM)
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    Dickkopf-related protein 4 (DKK4)
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    Dipeptidyl peptidase 1 (CTSC)
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    Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22)
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    Disintegrin and metalloproteinase domain-containing protein 23 (ADAM23)
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    Draxin (DRAXIN)
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    Ephrin type-B receptor 6 (EPHB6)
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    Ephrin-A4 (EFNA4)
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    Epithelial discoidin domain-containing receptor 1 (DDR1)
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    Ezrin (EZR)
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    Fc receptor-like protein 2 (FCRL2)
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    GDNF family receptor alpha-1 (GFRA1)
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    GDNF family receptor alpha-3 (GFRA3)
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    Galectin-8 (LGALS8)
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    Glial cell line-derived neurotrophic factor (GDNF)
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    Glypican-5 (GPC5)
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    Granulocyte colony-stimulating factor (CSF3)
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    Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (CSF2RA)
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    Granzyme A (GZMA)
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    Growth/differentiation factor 8 (MSTN)
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    Hydroxyacylglutathione hydrolase, mitochondrial (HAGH)
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    Interleukin-12 (IL12A_IL12B)
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    Interleukin-5 receptor subunit alpha (IL5RA)
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    Junctional adhesion molecule B (JAM2)
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    Kynureninase (KYNU)
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    Latexin (LXN)
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    Layilin (LAYN)
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    Leucine-rich repeat transmembrane protein FLRT2 (FLRT2)
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    Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2)
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    Linker for activation of T-cells family member 1 (LAT)
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    Lysosome membrane protein 2 (SCARB2)
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    MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (MDGA1)
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    Macrophage scavenger receptor types I and II (MSR1)
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    Matrilin-3 (MATN3)
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    Mesencephalic astrocyte-derived neurotrophic factor (MANF)
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    Microtubule-associated protein tau (MAPT)
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    N-acylethanolamine-hydrolyzing acid amidase (NAAA)
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    NT-3 growth factor receptor (NTRK3)
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    Neprilysin (MME)
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    Netrin receptor UNC5C (UNC5C)
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    Neuroblastoma suppressor of tumorigenicity 1 (NBL1)
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    Neurocan core protein (NCAN)
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    Neuronal cell adhesion molecule (NRCAM)
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    Neuropilin-2 (NRP2)
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    Neutral ceramidase (ASAH2)
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    Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMNAT1)
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    OX-2 membrane glycoprotein (CD200)
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    Platelet-derived growth factor receptor alpha (PDGFRA)
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    Plexin-B1 (PLXNB1)
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    Plexin-B3 (PLXNB3)
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    Poliovirus receptor (PVR)
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    Protogenin (PRTG)
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    R-spondin-1 (RSPO1)
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    RGM domain family member B (RGMB)
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    Repulsive guidance molecule A (RGMA)
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    Roundabout homolog 2 (ROBO2)
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    SPARC-related modular calcium-binding protein 2 (SMOC2)
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    Scavenger receptor class A member 5 (SCARA5)
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    Scavenger receptor class F member 2 (SCARF2)
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    Secreted frizzled-related protein 3 (FRZB)
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    Serine/threonine-protein kinase receptor R3 (ACVRL1)
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    Sialic acid-binding Ig-like lectin 9 (SIGLEC9)
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    Sialoadhesin (SIGLEC1)
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    Sphingomyelin phosphodiesterase (SMPD1)
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    Tenascin-R (TNR)
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    Testican-1 (SPOCK1)
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    Thy-1 membrane glycoprotein (THY1)
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    Transmembrane protease serine 5 (TMPRSS5)
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    Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)
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    Tumor necrosis factor receptor superfamily member 21 (TNFRSF21)
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    Tumor necrosis factor receptor superfamily member 27 (EDA2R)
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    UL16-binding protein 2 (ULBP2)
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    WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 (WFIKKN1)
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