Olink publications classified by application type

On this find you will find our latest publication list, with the papers categorized according to how the biomarker data obtained contributed to the study. Within each category, papers are grouped by year of publication and sorted alphabetically by first author. To jump directlpathoy to the areas of interest further down on this page, please click the appropriate link below.

Tip: To search for keywords of interest within the publication titles below, type Ctrl+F and enter your search term

Epidemiology/broader covariate analysis
Pathophysiology
Pathophysiology/Patient stratification
Patient stratification
Reviews/editorials
Surrogate endpoint
Technical evaluation
Technical evaluation/Pathophysiology
Wellness Studies

Data science

2024

Hédou J, Marić I, Bellan G, et al. Discovery of sparse, reliable omic biomarkers with Stabl. (2024) Nature Biotechnology, DOI: 10.1038/s41587-023-02033-x
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2023

Allesøe RL, Lundgaard AT, Hernández Medina R, et al. Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models. (2023) Nature Biotechnology, DOI: 10.1038/s41587-022-01520-x
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Barak O, Lovelace T, Piekos S, et al. Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes. (2023) BMC Medicine, DOI: 10.1186/s12916-023-03054-8
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Dimitsaki S, Gavriilidis GI, Dimitriadis VK and Natsiavas P, et al. Benchmarking of Machine Learning classifiers on plasma proteomic for COVID-19 severity prediction through interpretable artificial intelligence. (2023) Artificial Intelligence in Medicine, DOI: 10.1016/j.artmed.2023.102490
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Gauthier S, Tran-Dinh A, Morilla I. Plasma proteome dynamics of COVID-19 severity learnt by a graph convolutional network of multi-scale topology. (2023) Life Science Alliance, DOI: 10.26508/lsa.202201624
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Ha CSR, Müller-Nurasyid M, Petrera A, et al. Proteomics biomarker discovery for individualized prevention of familial pancreatic cancer using statistical learning. (2023) PLoS One, DOI: 10.1371/journal.pone.0280399
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Hartman E, Scott AM, Karlsson C, et al. Interpreting biologically informed neural networks for enhanced proteomic biomarker discovery and pathway analysis. (2023) Nature Communications, DOI: 10.1038/s41467-023-41146-4
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Vasaikar SV, Savage AK, Gong Q, et al. A comprehensive platform for analyzing longitudinal multi-omics data. (2023) Nature Communications, DOI: 10.1038/s41467-023-37432-w
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Xu Y, Ritchie SC, Liang Y, et al. An atlas of genetic scores to predict multi-omic traits. (2023) Nature, DOI: 10.1038/s41586-023-05844-9
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Zhou X, Chen Y, Ip FCF, et al. Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction. (2023) Communications Medicine, DOI: 10.1038/s43856-023-00269-x
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2022

Macdonald-Dunlop E, Taba N, Klarić L, et al. A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk. (2022) Aging, DOI: 10.18632/aging.203847
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Santos A, Colaço AR, Nielsen AB, et al.  A knowledge graph to interpret clinical proteomics data. (2022) Nature Biotechnology, DOI: 10.1038/s41587-021-01145-6
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Epidemiology/broader covariate analysis

2023

Stacey SN, Zink F, Halldorsson GH, et al. Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis. (2023) Nature Genetics, DOI: 10.1038/s41588-023-01555-z
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You J, Guo Y, Zhang Y, et al. Plasma proteomic profiles predict individual future health risk. (2023) Nature Communications, DOI: 10.1038/s41467-023-43575-7
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2022

Gadd DA, Hillary RF, McCartney DL,  et al. Epigenetic scores for the circulating proteome as tools for disease prediction. (2022) eLife, DOI: 10.7554/eLife.71802
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Matías-García P, Wilson R, Guo Q,  et al. Plasma Proteomics of Renal Function: A Trans-ethnic Meta-analysis and Mendelian Randomization Study. (2022) Journal of the American Society of Nephrology, DOI: 10.1681/ASN.2020071070
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Titova OE, Brunius C, Warensjö Lemming E, et al. Comprehensive analyses of circulating cardiometabolic proteins and objective measures of fat mass. (2023) International Journal of Obesity, DOI: 10.1038/s41366-023-01351-z
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Yang Z, MacDonald-Dunlop E, Chen J, et al. Genetic Landscape of the ACE2 Coronavirus Receptor. (2022) Circulation, DOI: 10.1161/CIRCULATIONAHA.121.057888
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2021

Drake I, Hindy G, Almgren P, et al.  Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort.(2021) Scientific Reports, DOI: 10.1038/s41598-021
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2020

Gyllensten U, Bosdotter Enroth S, Stålberg K, Sundfeldt K and Enroth S. Preoperative Fasting and General Anaesthesia Alter the Plasma Proteome. (2020) Cancers, DOI: 10.3390/cancers12092439
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Kuznetsova T and Cauwenberghs N.  Determinants of circulating angiotensin-converting enzyme 2 protein levels in the general population. (2020) Eur J Internal Medicine, DOI: 10.1016/j.ejim.2020.10.012
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Tebani A, Gummesson A, Zhong W, et al.  Integration of molecular profiles in a longitudinal wellness profiling cohort. (2020) Nature Communications, DOI: 10.1038/s41467-020-18148-7
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Zhong W, Gummesson A, Tebani A, et al.  Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort. (2020) Genome Medicine, DOI: 10.1186/s13073-020-00755-0
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2019

Dencker M,  Björgell O and Hlebowicz J. Effect of food intake on 92 oncological biomarkers by the Proseek Oncology II panel.  (2019) BMC Research Notes, doi.org/10.1186/s13104-019-4237-9
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Uhlén M et al. The human secretome. (2019) Science Signaling, DOI: 10.1126/scisignal.aaz0274
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2018

Dencker M, Gårdinger Y, Björgell O and Hlebowicz J. Effect of food intake on biomarkers for cardiovascular disease and inflammation analyzed with the Proseek Multiplex CVD II kit. (2018) Genetics and Molecular Research, DOI: 10.4238/gmr16039884
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Sundkvist A, Myte R, Bodén, S, Enroth S, Gyllensten U, Harlid S and van Guelpen B. Targeted plasma proteomics identifies a novel, robust association between cornulin and Swedish moist snuff. (2018) Scientific Reports, DOI:10.1038/s41598-018-20794-3
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2017

Ahsan M, Ek W, Rask-Andersen M, Karlsson T, Lind-Thomsen A, Enroth S, Gyllensten U and Johansson Å. The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases. (2017) PLOS Genetics, DOI: 10.1371/journal.pgen.1007005
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Dencker M, Björgell O and Hlebowicz J. Effect of food intake on 92 neurological biomarkers in plasma. (2017) Brain and Behaviour, DOI: 10.1002/brb3.747.
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Dencker M, Gårdinger Y, Björgell O, and Hlebowicz J. Effect of food intake on 92 biomarkers for cardiovascular disease (2017) PLOS One, doi.org/10.1371/journal.pone.0178656
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Shen Q, Björkesten J, Galli J, Ekman D, Broberg J, Nordberg N, Tillander A, Kamali-Moghaddam M, Tybring G and Landegren U. Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays. (2017) Clinical Chemistry and Laboratory Medicine, doi: 10.1515/cclm-2017-0648
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2016

Enroth S, Hallmans G, Grankvist K and Gyllensten, U. Effects of long-term storage time and original sampling month on biobank plasma protein concentrations. EBioMedicine (2016), 201608.038
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2015

Enroth S, Enroth SB, Johansson Å, Gyllensten U. Protein profiling reveals consequences of lifestyle choices on predicted biological aging. Sci Rep. (2015) Dec 1;5:17282. doi: 10.1038/srep17282
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Larsson A, Carlsson L, Gordh T, Lind A-L, Thulin M, Kamali-Moghaddam M. The effects of age and gender on plasma levels of 63 cytokines. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051.
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Larsson A, Carlsson L, Lind A-L, Gordh T, Bodolea C, Kamali-Moghaddam M, Thulin M. The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid. Cytokine. (2015) Jul 15. pii: S1043-4666(15)30020-X. doi: 10.1016/j.cyto.2015.07.010.
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2014

Enroth S, Johansson Å, Bosdotter Enroth S and Ulf Gyllensten U. Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. Nature Commun. (2014) Aug 22;5:4684. doi: 10.1038
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Pathophysiology/physiology

2024

Arredondo Eve A, Tunc E, Mehta D, et al. PFAS and their association with the increased risk of cardiovascular disease in postmenopausal women. (2024) Toxicological Sciences, DOI: 10.1093/toxsci/kfae065
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Baghdadi M, Nespital T, Monzó C, et al. Intermittent rapamycin feeding recapitulates some effects of continuous treatment while maintaining lifespan extension. (2024) Molecular Metabolism, DOI: 10.1016/j.molmet.2024.101902
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Baker T, Sharifian H, Newcombe PJ, et al. Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials. (2024) Annals of the Rheumatic Diseases, DOI: 10.1136/ard-2023-225445
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Bao A, Cornman H, Ma E, et al. Dupilumab therapy modulates circulating inflammatory mediators in patients with prurigo nodularis. (2024) JID Innovations, DOI: 10.1016/j.xjidi.2024.100281
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Baranova A, Luo J, Fu L, et al. Evaluating the effects of circulating inflammatory proteins as drivers and therapeutic targets for severe COVID-19. (2024) Frontiers in Immunology, DOI: 10.3389/fimmu.2024.1352583
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Baril AA, Picard C, Labonté A, et al. Longer sleep duration and neuroinflammation in at-risk elderly with a parental history of Alzheimer’s disease. (2024) Sleep, DOI: 10.1093/sleep/zsae081
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Bayes-Genis A, Gastelurrutia P, Monguió-Tortajada M, et al. Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trial. (2024) EBioMedicine, DOI: 10. 1016/j.ebiom.2024. 105060
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Becker AMD, Decker AH, Flórez-Grau G, et al. Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential. (2024) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2023.101386
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Beuthner BE, Elkenani M, Evert K, et al. Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement. (2024) ESC Heart Failure, DOI: 10.1002/ehf2.14709
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Beydoun MA, Beydoun HA, Hu YH, et al. Plasma proteomic biomarkers and the association between poor cardiovascular health and incident dementia: The UK Biobank study. (2024) Brain, Behavior, and Immunity, DOI: 10.1016/j.bbi.2024.05.005
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Bier K, Senajova Z, Henrion F, et al. Interleukin-26 potentiates type 2 skin inflammation in presence of interleukin-1β. (2024) The Journal of Investigative Dermatology, DOI: 10.1016/j.jid.2023.12.018
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Bister J, Filipovic I, Sun D, et al. Tissue-specific nonheritable influences drive endometrial immune system variation. (2024) Science Immunology, DOI: 10.1126/sciimmunol.adj7168
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Blanco-Heredia J, Souza CA, Trincado JL, et al. Converging and evolving immuno-genomic routes toward immune escape in breast cancer. (2024) Nature Communications, DOI: 10.1038/s41467-024-45292-1
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Boahen CK, Abee H, Ponce IR, et al. Sex-biased genetic regulation of inflammatory proteins in the Dutch population. (2024) BMC Genomics, DOI: 10.1186/s12864-024-10065-z
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Bremer SJ, Boxnick A, Glau L, et al. Thymic Atrophy and Immune Dysregulation in Infants with Complex Congenital Heart Disease. (2024) Journal of Clinical Immunology, DOI: 10.1007/s10875-024-01662-4
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Briggs K, Tomar V, Ollberding N, et al. Crohn’s Disease-Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism. (2024) Inflammatory Bowel Diseases, DOI: 10.1093/ibd/izae003
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Brown RB, Tozer DJ, Loubière L, et al. MINocyclinE to Reduce inflammation and blood-brain barrier leakage in small Vessel diseAse (MINERVA): A phase II, randomized, double-blind, placebo-controlled experimental medicine trial. (2024) Alzheimer’s & Dementia, DOI: 10.1002/alz.13830
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Bull CJ, Hazelwood E, Legge DN, et al. Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes. (2024) eBioMedicine, DOI: 10.1016/j.ebiom.2024.104977
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Bulut O, Temba GS, Koeken VACM, et al. Common and distinct metabolomic markers related to immune aging in Western European and East African populations. (2024) Mechanisms of Ageing and Development, DOI: 10.1016/j.mad.2024.111916
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Carlsson H, Brudin L, Serrander L, et al.  Cell-Mediated Proteomics, and Serological and Mucosal Humoral Immune Responses after Seasonal Influenza Immunization: Characterization of Serological Responders and Non-Responders. (2024) Vaccines, DOI: 10.3390/vaccines12030303
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Cattaneo M, Baragetti A, Malovini A, et al. Longevity-associated BPIFB4 gene counteracts the inflammatory signaling. (2024) Immunity & Ageing, DOI: 10.1186/s12979-024-00424-5.
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Chen Z, Guo Y, Sun H, et al. Exploration of the causal associations between circulating inflammatory proteins, immune cells, and neuromyelitis optica spectrum disorder: a bidirectional Mendelian randomization study and mediation analysis. (2024) Frontiers in Aging Neuroscience, DOI: /10.3389/fnagi.2024.1394738
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Coffey DG, Osman K, Aleman A, et al. Phase 1 study combining elotuzumab with autologous stem cell transplant and lenalidomide for multiple myeloma. (2024) Journal for Immunotherapy of Cancer, DOI: 10.1136/jitc-2023-008110
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Compte R, Freidin MB, Granville Smith I, et al. No evidence of association between either Modic change or disc degeneration and five circulating inflammatory proteins. (2024) JOR Spine, DOI: 10.1002/jsp2.1323
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Cordano C, Werneburg S, Abdelhak A, et al. Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis. (2024) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2024.101490
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Crestani E, Benamar M, Phipatanakul W, et al. Age-specific Metabolomic profiles in children with food allergy. (2024) Clinical Immunology, DOI: 10.1016/j.clim.2024.109928.
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Cuesta-Lopez L, Escudero-Contreras A, Hanaee Y, et al. Exploring Candidate Biomarkers for Rheumatoid Arthritis through Cardiovascular and Cardiometabolic Serum Proteome Profiling. (2024) Frontiers in Immunology, DOI: 10.3389/fimmu.2024.1333995
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da Costa JJ, Christ L, Villiger PM, et al. Anti-IL-6 Receptor Treatment in Giant Cell Arteritis Patients Reduces Levels of IL-1β-Receptor Antagonist but Not IL-1β. (2024) Rheumatology, DOI: 10.3390/rheumato4020006
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Deng YT, Wu BS, Yang L, et al. Large-scale whole-exome sequencing of neuropsychiatric diseases and traits in 350,770 adults. (2024) Nature Human Behaviour, DOI: 10.1038/s41562-024-01861-4
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Dos Santos JC, Moreno M, Teufel LU, et al. Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity. (2024) Cell Reports, DOI: 10.1016/j.celrep.2024.113932
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Drenthen LCA, Ajie M, de Baaij JHF, et al. Magnesium supplementation modulates T-cell function in people with type 2 diabetes and low serum magnesium levels. (2024) The Journal of Clinical Endocrinology and Metabolism, DOI: 10.1210/clinem/dgae097
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Drost CC, Rovas A, Osiaevi I, et al. Interleukin-6 drives endothelial glycocalyx damage in COVID-19 and bacterial sepsis. (2024) Angiogenesis, DOI: 10.1007/s10456-024-09916-w
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Drzeniek NM, Kahwaji N, Picht S, et al. In Vitro Transcribed mRNA Immunogenicity Induces Chemokine-Mediated Lymphocyte Recruitment and Can Be Graduallgy Tailored by Uridine Modification. (2024) Advanced Science, DOI: 10.1002/advs.202308447
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Ea HK, Kischkel B, Chirayath TW, et al. Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker. (2024) Annals of the Rheumatic Diseases, DOI: 10.1136/ard-2023-225305
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Elbagir S, Mohammed NA, Oke V, at al. Anti-histone and anti-nucleosome rather than anti-dsDNA antibodies associate with IFN-induced biomarkers in Sudanese and Swedish Systemic Lupus Erythematosus patients. (2024) Rheumatology, DOI: 10.1093/rheumatology/keae134
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Enström A, Carlsson R, Buizza C, et al. Pericyte-Specific Secretome Profiling in Hypoxia Using TurboID in a Multicellular In Vitro Spheroid-Model. (2024) Molecular and Cellular Proteomics, DOI: 10.1016/j.mcpro.2024.100782
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Ferreira JP, Packer M, Sattar N, et al. Insulin-like growth factor binding protein-7 concentrations in chronic heart failure: Results from the EMPEROR programme. (2024) European Journal of Heart Failure, DOI: 10.1002/ejhf.3227
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Fransén K, Hiyoshi A, Paramel GV, et al. Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study. (2024) BMC Cardiovascular Disorders, DOI: 10.1186/s12872-024-03765-7
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Frusone V, Maurer K, Emanuel BS, et al. Inflammatory Proteomic Analysis of 22q11.2 Deletion Syndrome. (2024) Journal of Clinical Immunology, DOI: 10.1007/s10875-024-01689-7
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Gaceb A, Roupé L, Enström A, et al. Pericyte Microvesicles as Plasma Biomarkers Reflecting Brain Microvascular Signaling in Patients With Acute Ischemic Stroke. (2024) Stroke, DOI: 10.1161/STROKEAHA.123.045720
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Ghouse J, Sveinbjörnsson G, Vujkovic M, et al. Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis. (2024) Nature Genetics, DOI: 10.1038/s41588-024-01720-y
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Glass DR, Mayer-Blackwell K, Ramchurren N, et al. Multi-omic profiling reveals the endogenous and neoplastic responses to immunotherapies in cutaneous T cell lymphoma. (2024) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2024.101527
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Glitza IC, Seo YD, Spencer CN, et al. Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity. (2024) Cancer Discovery, DOI: 10.1158/2159-8290.CD-24-0066
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Goldberg DT, Yaskolka Meir A, Tsaban G, et al. Novel proteomic signatures may indicate MRI-assessed intrahepatic fat state and changes; the DIRECT PLUS clinical trial. (2024) Hepatology, DOI: 10.1097/HEP.0000000000000867
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Greenman R, Snir T, Katav A, et al. The Role of CCL24 in Primary Sclerosing Cholangitis: Bridging Patient Serum Proteomics to Preclinical Data. (2024) Cells, DOI: 10.3390/cells13030209
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Guo W, Zhao L, Huang W, et al. Sodium-glucose cotransporter 2 inhibitors, inflammation, and heart failure: a two-sample Mendelian randomization study. (2024) Cardiovascular Diabetology, DOI: 10.1186/s12933-024-02210-5
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Gurung RL, Zheng H, Koh HWL, et al. Plasma proteomics of diabetic kidney disease among Asians with younger-onset type 2 diabetes. (2024) The Journal of Clinical Endocrinology and Metabolism, DOI: 10.1210/clinem/dgae266
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Hayderi A, Kumawat AK, Shavva VS, et al. RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells. (2024) Scientific Reports, DOI: 10.1038/s41598-024-58592-9
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He S, Lundberg B, Hallberg J, et al. Joint association of air pollution exposure and inflammation-related proteins in relation to infant lung function. (2024) International Journal of Hygiene and Environmental Health, DOI: 10.1016/j.ijheh.2023.114294
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Hmila I, Hill J, Shalaby KE, et al. Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development. (2024) Ecotoxicology and Environmental Safety, DOI: 10.1016/j.ecoenv.2024.116070
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Hoyer A, Chakraborty S, Lilienthal I, et al. The functional role of CST1 and CCL26 in asthma development. (2024) Immunity, Inflammation and Disease, DOI: 10.1002/iid3.1162
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He XY, Wu BS, Yang L, et al. Genetic associations of protein-coding variants in venous thromboembolism. (2024) Nature Communications, DOI: 10.1038/s41467-024-47178-8
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Hellgren F, Rosdahl A, Arcoverde Cerveira R, et al. Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans. (2024) JCI Insight, DOI: 10.1172/jci.insight.175401
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Hu W, Liu Y, Lian C, et al. Genetic insight into putative causes of xanthelasma palpebrarum: a Mendelian randomization study. (2024) Frontiers in Immunology, DOI: 10.3389/fimmu.2024.1347112
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Hu Y, Lin L, Zhang L, et al. Identification of Circulating Plasma Proteins as a Mediator of Hypertension-Driven Cardiac Remodeling: A Mediation Mendelian Randomization Study. (2024) Hypertension, DOI: 10.1161/HYPERTENSIONAHA.123.22504
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Huang ZL, Huang ZH, Xie Y, et al. Inflammatory factors mediated the effect of air pollution on ischemic stroke: a two-step, mediation Mendelian randomization study. (2024) European Review for Medical and Pharmacological Sciences, DOI: 10.26355/eurrev_202403_35610
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Jiang S, Li X, Li Y, et al. APOE from patient-derived astrocytic extracellular vesicles alleviates neuromyelitis optica spectrum disorder in a mouse model. (2024) Science Translational Medicine, DOI: 10.1126/scitranslmed.adg511
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Jolly AA, Brown RB, Tozer DJ, et al. Are Central and Systemic Inflammation associated with Fatigue in Cerebral Small Vessel Disease? (2024) International Journal of Stroke, DOI: 10.1177/17474930241245613
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Kasher M, Freidin M, Williams F, et al. GlycA and CRP Are Genetically Correlated: Insight into the Genetic Architecture of Inflammageing (2024) Biomolecules, DOI: 10.3390/biom14050563
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Keppeler K, Pesi A, Lange S, et al. Vascular dysfunction and arterial hypertension in experimental celiac disease are mediated by gut-derived inflammation and oxidative stress. (2024) Redox Biology, DOI: 10.1016/j.redox.2024.103071
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Klevebro S, Kebede Merid S, Sjöbom U, et al. Arachidonic acid and docosahexaenoic acid levels correlate with the inflammation proteome in extremely preterm infants. (2024) Clinical Nutrition, DOI: 10.1016/j.clnu.2024.03.031
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Kojima R, Paslawski W, Lyu G, et al. Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson’s Disease Patients with GBA1 Mutations. (2024) International Journal of Molecular Sciences, DOI: 10.3390/ijms25010683
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Kragsnaes MS, Jensen JRB, Nilsson AC, et al. Dynamics of inflammation-associated plasma proteins following faecal microbiota transplantation in patients with psoriatic arthritis and healthy controls: exploratory findings from the FLORA trial. (2024) RMD Open, DOI: 10.1136/rmdopen-2023-003750
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Krauss RM, Fisher LM, King SM, et al. Changes in Soluble LDL Receptor and Lipoprotein Fractions in Response to Diet in the DIETFITS Weight Loss Study. (2024) Journal of Lipid Research, DOI: 10.1016/j.jlr.2024.100503
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Krupka S, Hoffmann A, Jasaszwili M, et al. Consequences of COVID-19 on Adipose Tissue Signatures. (2024) International Journal of Molecular Sciences, DOI: 10.3390/ijms25052908
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Lang A, Binneboessel S, Nienhaus F, et al. Acute and short-term fluctuations in gravity are associated with changes in circulatory plasma protein levels. (2024) NPJ Microgravity, DOI: 10.1038/s41526-024-00370-y
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Laudanski K, Mahmoud M, Ahmed A, et al. Immunological Signatures in Blood and Urine in 80 Individuals Hospitalized during the Initial Phase of COVID-19 Pandemic with Quantified Nicotine Exposure. (2024) International Journal of Molecular Sciences, DOI: 10.3390/ijms25073714
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Lechner K, Kia S, von Korn P, et al. Cardiometabolic and immune response to exercise training in patients with metabolic syndrome: retrospective analysis of two randomized clinical trials. (2024) Frontiers in Cardiovascular Medicine, DOI: 10.3389/fcvm.2024.1329633
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Li C, Ke B, Chen J, et al. Systemic inflammation and risk of Parkinson’s disease: A prospective cohort study and genetic analysis. (2024) Brain, Behavior, and Immunity, DOI: 10.1016/j.bbi.2024.02.013
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Li H, Du S, Dai J, et al. Proteome-Wide Mendelian Randomization identifies causal plasma proteins in lung cancer. (2024) iScience, DOI: 10.1016/j.isci.2024.108985
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Li H, Lin J, Yang K, et al. Inflammatory proteomics analysis in different types of male androgenetic alopecia. (2024) Archives of Dermatological Research, DOI: 10.1007/s00403-024-02819-2
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Liang YC, Jia MJ, Li L, et al. Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study. (2024) Frontiers in Endocrinology, DOI: 10.3389/fendo.2024.1358311
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Lin H and Cao B. Circulating VEGF and inflammatory bowel disease: a bidirectional mendelian randomization. (2024) Frontiers in Genetics, DOI: 10.3389/fgene.2024.1282471
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Lin JS, Petrera A, Hauck SM, et al Associations of Proteomics With Hypertension and Systolic Blood Pressure: KORA S4/F4/FF4 and KORA-Age1/Age2 Cohort Studies. (2024) Hypertension, DOI: 10.1161/HYPERTENSIONAHA.123.22614
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Lindborg SR, Goyal NA, Katz J, et al. Debamestrocel multimodal effects on biomarker pathways in amyotrophic lateral sclerosis are linked to clinical outcomes. (2024) Muscle & Nerve, DOI: 10.1002/mus.28093
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Lindblad A,  Persson K and Demirel I. IL-1RA is part of the inflammasome-regulated immune response in bladder epithelial cells and influences colonization of uropathogenic E. Coli  (2019) Cytokine, DOI: 10.1016/j.cyto.2019.154772
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Zheng J, Maerz W, Gergei I et. al. Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures. (2019) Journal of Bone and Mineral Research, DOI: 10.1002/jbmr.3803
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Zhou H, Xi L, Ziemek D, O’Neil S, Lee J, Stewart Z, Zhan Y, Zhao S, Zhang Y, Page K, Huang A, Maciejewski M, Zhang B, Gorelick K, Fitz L, Pradhan V, Cataldi F, Vincent M, von Schack D, Hung K and Hassan-Zahraee M. Molecular Profiling of Ulcerative Colitis Subjects from the TURANDOT Trial Reveals Novel Pharmacodynamic/ Efficacy Biomarkers. (2019) Journal of Crohns and Colitis, doi.org/10.1093/ecco-jcc/jjy217
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2018

Abrahamsson A, Rzepecka A and Dabrosin C. Equal Pro-inflammatory Profiles of CCLs, CXCLs, and Matrix Metalloproteinases in the Extracellular Microenvironment In Vivo in Human Dense Breast Tissue and Breast Cancer.(2018) Frontiers in Immunology, doi: 10.3389/fimmu.2017.01994
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Aqrawi L, Ivanchenko M, Björk A, Ramírez Sepúlveda J, Imgenberg-Kreuz J, Kvarnström M, Haselmayer P, Jensen J, Nordmark G, Chemin K, Skarstein G and Wahren-Herlenius M. Diminished CXCR5 expression in peripheral blood of patients with Sjögren’s syndrome may relate to both genotype and salivary gland homing. (2018) Clinical & Experimental  Immunology, doi: 10.1111/cei.13118
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Al-Talabany S, Mordi I, Houston G, Colhoun H, Weir-McCall J, Matthew S, Looker H, Levin D, Belch J, Dove F, Khan F and Lang C. Epicardial adipose tissue is related to arterial stiffness and inflammation in patients with cardiovascular disease and type 2 diabetes. (2018) BMC Cardiovascular Disorders, doi.org/10.1186/s12872-018-0770-z
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Barwari T, Eminaga S, Mayr U, Lu R, Armstrong P, Chan M, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley S, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah A, Ghevaert C, Warner T, Fernández-Hernando C, Suárez Y and Mayr M. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. (2018) Journal of Clinical Investigation, doi.org/10.1172/jci.insight.123335.
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Bhandage A, Jin Z, Korol S, Shenb Q, Pe Y, Deng Q, Espes D, Carlsson P-O, Kamali-Moghaddamb M and Birnir B. GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.03.019
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Bränn E, Fransson E, White R, Papadopoulos F, Edvinsson Å, Kamali‐Moghaddam M, Cunningham J, Sundström‐Poromaa I and Skalkidou  A. Inflammatory markers in women with postpartum depressive symptoms (2018) Journal of Neuroscience Research, doi.org/10.1002/jnr.24312
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Caja L,Tzavlaki K, Dadras M, Tan E-J, Hatem G, Maturi N, Morén A, Wik L, Watanabe Y, Savary K, Kamali-Moghaddan M, Uhrbom L, Heldin C-H and Moustakas A. Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells. (2018) Oncogene, doi:10.1038/s41388-018-0136-0
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Chowdhury R, Vallania F, Yang Q, Lopez Angel C, Darboe F, Penn-Nicholson A, Rozot V, Nemes E, Malherbe S, Ronacher K, Walzl G, Hanekom W, Davis M, Winter J, Chen X, Scriba T, Khatri P and Chien Y-H. A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes (2018) Nature, doi: 10.1038/s41586-018-0439-x
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Defilippi C, Lo J, Christenson R, Grundberg I, Stone L, Zanni M, Lee H and Grinspoon S. Novel mediators of statin effects on plaque in HIV: a proteomics approach. (2018) AIDS, doi.org/10.1097/QAD.0000000000001762
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Edvinsson Å, Bränn E,  Hellgren C, Freyhult E, White R, Kamali-Moghaddam M, Olivier J, Bergquist J, Boström A, Schiöth H, Skalkidou A, Cunningham J and Sundström-Poroma  I. Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction. (2018) Psychoneuroendocrinology, doi: 10.1016/j.psyneuen.2017.02.027
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Enroth S, Maturi, V, Berggrundi, M, Bosdotter Enroth S, Moustakas A, Johansson Å and Gyllensten U. Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases. (2018) Scientific Reports, DOI:10.1038/s41598-018-23860-y
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Grufman H, Yndigegn T, Gonçalves I, Nilsson J and Schiopu A. Elevated IL-27 in patients with acute coronary syndrome is associated with adverse ventricular remodeling and increased risk of recurrent myocardial infarction and cardiovascular death (2018) Cytokine, doi.org/10.1016/j.cyto.2017.11.002
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Halak S, Östling G, Edsfeldt A, Kennbäck C, Dencker M, Gonçalves I and Asciutto G. Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms (2018) Cerebrovascular Diseases Extra, doi.org/10.1159/000485258
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Herder C, Kannenberg J, Carstensen-Kirberg M, Strom A, Bönhof G, Rathmann W, Huth C, Koenig W, Heier M, Krumsiek J, Peters A, Meisinger C, Roden M, Thorand B and Ziegler D. A Systemic Inflammatory Signature Reflecting Crosstalk Between Innate and Adaptive Immunity Is Associated With Incident Polyneuropathy: KORA F4/FF4 Study (2018) Diabetes, doi: 10.2337/db18-0060
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Holm Nielsen S, Tengryd C, Edsfeldt A, Brix S, Genovese F, Bengtsson E, Karsdal M, Leeming D, Nilsson J and Goncalves I. Markers of Basement Membrane Remodeling Are Associated With Higher Mortality in Patients With Known Atherosclerosis. (2018) Journal of the American Heart Association, DOI: 10.1161/JAHA.118.009193
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Johansson M, Ricci F, Aung N, Sutton R, Melander O and  Fedorowski A. Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension (2018) Hypertension, doi.org/10.1161/HYPERTENSIONAHA.117.10365
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Johansson M, Ricci F, Aung N, Sutton R, Melander O and  Fedorowski A. Inflammatory biomarker profiling in classical orthostatic hypotension: Insights from the SYSTEMA cohort (2018) Int. J. Cadiol., doi.org/10.1016/j.ijcard.2017.12.020
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Kulasingam A, Hvas A-M, Lerkevang Grove E, Løkke Funck K and Dalby Kristensen S. Detection of biomarkers using a novel proximity extension assay in patients with ST-elevation myocardial infarction. (2018) Thrombosis Research, doi.org/10.1016/j.thromres.2018.10.011
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Kuschnerus K, Straessler E, Müller M, Lüscher T, Landmesser U and Kränkel N. Increased Expression of miR-483-3p Impairs the Vascular Response to Injury in Type 2 Diabetes. (2018) Diabetes, doi.org/10.2337/db18-0084
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Lagali N, Badian R, Liu X, Feldreich T, Ärnlöv J, Paaske Utheim T, Dahlin L and Rolandsson O. Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9. (2018) Scientific Reports, DOI:10.1038/s41598-018-32410-5
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Lampinen M, Vessby J, Fredricsson A, Wanders A, Rorsman F and Carlson M. High Serum sCD40 and a Distinct Colonic T Cell Profile in Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. (2018) Journal of Crohn’s and Colitis, doi.org/10.1093/ecco-jcc/jjy170
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Lareyre F, Moratal C, Chikande J, Jean-Baptiste E, Hassen-Khodja R, Neels J, Chinetti G and Raffort J. Investigation of Plasma Inflammatory Profile in Diabetic Patients With Abdominal Aortic Aneurysm: A Pilot Study (2018) Vascular and Endovascular Surgery, doi:/10.1177/1538574418784717
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Ljungberg J, Janiec M, Bergdah I, Holmgren A, Hultdin J, Johansson B, Näslund U, Siegbahn A, Fall T and Söderberg S. Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement. (2018) Circulation, doi.org/10.1161/CIRCULATIONAHA.117.030414
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Löfgren M, Svala E, Lindahl A, Skiöldebrand E and Ekman S. Time-dependent changes in gene expression induced in vitro by interleukin-1β in equine articular cartilage. (2018) Research in Veterinary Science, doi.org/10.1016/j.rvsc.2018.04.013
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Manor O, Zubair N, Conomos M, Xu X, Rohwer J, Krafft C, Lovejoy J and Magis A. A Multi-omic Association Study of Trimethylamine N-Oxide. (2018) Cell Reports, DOI: 10.1016/j.celrep.2018.06.096
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Mardinoglu A , Wu H , Bjornson E , Zhang  C, Hakkarainen A , Rasanen S , Lee S , Mancina R , Bergentall  M , Pietilainen K , Soderlund  S , Matikainen N , Stahlman M , Bergh, P-O , Adiels  M , Piening B, Graner M , Lundbom N , Williams K, Romeo S , Nielsen  J , Snyder M , Uhlen M , Bergstrom G , Perkins R , Marschall H-U , Backhed F , Taskinen M-R and Boren J. An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. (2018) Cell Metabolism, doi.org/10.1016/j.cmet.2018.01.005
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Monaghan T, Mullish B, Patterson J, Wong G, Marchesi J, Xu H, Jilani T and Kao D. Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway. (2018) Gut Microbes, doi: 10.1080/19490976.2018.1506667
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Natali A, Nesti L, Venturi E, Shore A, Khan F, Gooding K, Gates P, Looker H, Dove F, Goncalves I, Persson M and Nilsson J. Metformin is the key factor for elevated plasma GDF‐15 levels in type 2 diabetes: a nested, case‐control study. (2018) Diabetes, Obesity and Metabolism, doi.org/10.1111/dom.13519
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Nuora A, Tupasela T, Jokioja J, Tahvonen R, Kallio H, Yanga B, Viitanen M and Linderborg K. The effect of heat treatments and homogenisation of cows’ milk on gastrointestinal symptoms, inflammation markers and postprandial lipid metabolism (2018) International Dairy Journal, doi.org/10.1016/j.idairyj.2018.05.017
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Olin A,  Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, Gustafsson A, Bernhardsson AK, Zhang C, Bohlin K and Brodin P. Stereotypic immune system development in newborn children. (2018) Cell, doi.org/10.1016/j.cell.2018.06.045.
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Palma M, Krstic A, Peña Perez L, Berglöf A, Meinke S, Wang Q, Blomberg KE, Kamali‐Moghaddam M, Shen Q, Jaremko G, Lundin J, De Paepe A, Höglund P, Kimby E, Österborg A, Månsson R and Smith E. Ibrutinib induces rapid down‐regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia‐related genes in blood and lymph nodes. (2018) British Journal of Haematology, doi.org/10.1111/bjh.15516
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Pan J, Michaëlsson E, Shaw P, Kuruvilla S, Kramer C, Gan L-M, Keeley E, and Salerno, M. Extracellular volume by cardiac magnetic resonance is associated with biomarkers of inflammation in hypertensive heart disease. (2018) Journal of hypertension, doi: 10.1097/HJH.0000000000001875
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Panezai J, Ghaffar A, Altamash M, Engström P-E and Larsson A. Periodontal disease influences osteoclastogenic bone markers in subjects with and without rheumatoid arthritis. (2018) PLOS ONE, doi.org/10.1371/journal.pone.0197235
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Piening B, Zhou W, Contrepois K, Röst H, Urban G, Mishra T, Hanson B, Bautista E, Leopold S, Yeh C, Spakowicz D, Banerjee I, Chen C, Kukurba K, Perelman D, Craig C, Colbert E, Salins D, Rego S, Lee S, Zhang C, Wheeler J, Sailani R, Liang L, Abbott C, Gerstein M, Mardinoglu A, Smith U, Rubin D, Pitteri S, Sodergren E, McLaughlin T, Weinstock G and Snyder M. Integrative Personal Omics Profiles during Periods of Weight Gain and Loss (2018) Cell Systems, doi.org/10.1016/j.cels.2017.12.013
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Rattik S, Engelbertsen D, Wigren M, Ljungcrantz I,  Östling G, Persson M, Nordin Fredrikson G, Bengtsson E, Nilsson  J and Björkbacka H. Elevated circulating effector memory T cells but similar levels of regulatory T cells in patients with type 2 diabetes mellitus and cardiovascular disease.  (2018) Diabetes and Vascular Disease Research, DOI: 10.1177/1479164118817942
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Santema B, Kloosterman M, Van Gelder I, Mordi I, Lang C, Lam C, Anker S, Cleland J, Dickstein K, Filippatos G, Van der Harst P, Hillege H, Ter Maaten J, Metra M, Ng L, Ponikowski P, Samani N, Van Veldhuisen D, Zwinderman A, Zannad F, Damman K, Van der Meer P, Rienstra M and Voors A. Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction. (2018) European Heart Journal, doi:10.1093/eurheartj/ehy421
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Schlesinger S, Herder C, Kannenberg J, Huth C, Carstensen-Kirberg M, Rathmann W, Bönhof G, Koenig W, Heier M, Peters A, Meisinger C, Roden M, Thorand B and Ziegler D. General and Abdominal Obesity and Incident Distal Sensorimotor Polyneuropathy: Insights Into Inflammatory Biomarkers as Potential Mediators in the KORA F4/FF4 Cohort. (2018) Diabetes Care, doi.org/10.2337/dc18-1842
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Solheim N, Gregersen I, Halvorsen B, Bjerkeli V, Stubhaug A, Gordh T and Rosseland L. Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery. (2018) Acta Anaesthesiologica Scandinavica, doi:10.3390/ijms18122697
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Sperk M, Zhang W, Nowak P and Neogi U. Plasma soluble factor following two decades prolonged suppressive antiretroviral therapy in HIV-1-positive males. (2018) Medicine, doi, 10.1097/MD.0000000000009759
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Sun B, Maranville J, Peters J, Stacey D, Staley J, Blackshaw J, Burgess S, Jiang T, Paige E, Surendran P, Oliver-Williams C, Kamat M, Prins B, Wilcox S, Zimmerman E, Chi A, Bansal N, Spain S, Wood A, Morrel N, Bradley J, Janjic N, Roberts D, Ouwehand W. Todd J, Soranzo N. Suhre K, Dirk D,  Fox C, Plenge R, Danesh J, Runz H and Butterworth A. Genomic atlas of the human plasma proteome (2018) Nature,  doi: 10.1038/s41586-018-0175-2
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Sällman Almén M, Björk J, Nyman U, Lindström V, Jonsson M, Abrahamson M, Schiller Vestergren A, Lindhe Ö, Franklin G, Christensson A and Grubb A. Shrunken pore syndrome is associated with increased levels of atherosclerosis promoting proteins. (2018) Kidney International Reports, doi.org/10.1016/j.ekir.2018.09.002.
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Toribio M, Fitch K, Stone L, Zanni M, Loa J, de Filippi C, Sponseller C, Lee H, Grundberg I, Thompson M, Aberg J and Grinspoon S. Assessing statin effects on cardiovascular pathways in HIV using a novel proteomics approach: Analysis of data from INTREPID, a randomized controlled trial. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.08.039
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Tromp J, Westenbrink D, Ouwerkerk W, van Veldhuisen D, Samani N, Ponikowski P, Metra M, Anker S, Cleland J, Dickstein K,  Filippatos G, van der Harst P, Lang, C, Ng L, Zannad F, Zwinderman A, Hillege H, van der Meer P and Voors A. Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction. (2018) JACC, doi.org/10.1016/j.jacc.2018.06.050
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Vossen A, van der Zee1 H, Davelaar N, Mus A, van Doorn M and Prens E. Apremilast for moderate hidradenitis suppurativa: no significant change in lesional skin inflammatory biomarkers. (2018) Journal of the European Academy of Dermatology and Venereology, doi.org/10.1111/jdv.15354
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Vroegindewey M, Oemrawsingh R, Kardys I, Asselbergs F, van der Harst P, Oude Ophuis A, Cramer G, Maas A, Hong Kie The S, Wardeh A, Mouthaan H, Boersma E and Akkerhuis M. The temporal pattern of immune and inflammatory proteins prior to a recurrent coronary event in post-acute coronary syndrome patients. (2018) Biomarkers, doi: 10.1080/1354750X.2018.1539768
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Wigren M, Svenugnsson E, Yao Mattisson I, Gustafsson J, Gunnarsson I, Zickert A, Elvin K, Jensen-Urstad K, Bengtsson A, Gullstrand B, Nordin Fredrikson G and Nilsson J. Cardiovascular disease in systemic lupus erythematosus is associated with increased levels of biomarkers reflecting receptor-activated apoptosis (2018) Atherosclerosis, doi: 10.1016/j.atherosclerosis.2018.01.022
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Yeung V, Webber J, Dunlop E, Morgan H, Hutton J, Gurney M, Jones E, Falcon-Perez J, Tabi Z, Errington R and Clayton A. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma (2018) Nanoscale, doi/10.1039/C8NR02417K
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Zhernakova D, Le T, Kurilshikov A, Atanasovska B, Bonder M, Sanna S, Claringbould A, Võsa U, Deelen P, LifeLines cohort study, BIOS consortium, Franke L, de Boer R, Kuipers F, Netea M, Hofker M, Wijmenga C, Zhernakova A and Fu J. Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome. (2018) Nature Genetics, doi.org/10.1038/s41588-018-0224-7
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2017

Bayes-Genis A, Núñez J, Zannad F, Ferreira J, Anker S, Cleland J, Dickstein K, Filippatos G, Lang C, Ng L, Ponikowski P, Samani N, van Veldhuisen D, , Zwinderman A, Metra M, Lupón J and Voors A. The PCSK9-LDL Receptor Axis (2017) J. Am. College Cardiology, doi: 10.1016/j.jacc.2017.08.057
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Bergthorsdottir R, Ragnarsson O, Skrtic S, Glad K, Nilsson S, Louis Ross I, Leonsson-Zachrisson M and Johannsson G. Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients with Addison’s Disease; a case-control study (2017) The Journal of Clinical Endocrinology & Metabolism, doi.org/10.1210/jc.2017-01324
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Björkbacka H, Yao Mattisson I, Wigren M, Melander O, Fredrikson G, Bengtsson E, Gonçalves I, Almgren P, Lagerstedt J, Orho-Melander M, Engström G and Nilsson J. Plasma stem cell factor levels are associated with risk of cardiovascular disease and death. (2017) Journal of Internal Medicine, doi/10.1111/joim.12675
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Brodin P & Davis M. Human immune system variation (2017), Nat. Rev. Immunol, 17, 21-29
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Brunner P, Suárez-Fariñas M, He H, Malik K, Wen H-C, Gonzalez J, Chan T, Estrada Y, Zheng X, Khattri S, Dattola N, Krueger J and Guttman-Yassky E. The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins. (2017) Scientific Reports, DOI:10.1038/s41598-017-09207-z
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Bäckryd E, Lind A-L, Thulin M,  Larsson A, Gerdle B and Gordh T. High levels of cerebrospinal fluid chemokines point to the presence of neuroinflammation in peripheral neuropathic pain: a cross-sectional study of 2 cohorts of patients compared with healthy controls. (2017) Pain, doi:10.1097/j.pain.0000000000001061
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Carlsson A,Ingelsson E, Sundström J, Carrero J, Gustafsson S, Feldreich T, Stenemo M, Larsson A, Lind L and Ämlöv J.Use of Proteomics To Investigate Kidney Function Decline over 5 Years. Clinical Journal of the American Society of Nephrology (2017), doi: 10.2215/CJN.08780816
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Cornelis M,   Gustafsson S,  Ärnlöv J, Elmståhl S, Söderberg S,  Sundström J,   Michaëlsson K,  Lind L and Ingelsson E. Targeted proteomic analysis of habitual coffee consumption. (2017) Journal of Internal Medicine, doi.org/10.1111/joim.12703
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Dencker M, Björgell O and Hlebowicz J. Effect of food intake on 92 neurological biomarkers in plasma. (2017) Brain and Behaviour, DOI: 10.1002/brb3.747.
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Dencker M, Gårdinger Y, Björgell O, and Hlebowicz J. Effect of food intake on 92 biomarkers for cardiovascular disease (2017) PLOS One, doi.org/10.1371/journal.pone.0178656
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Drum C, Tan W, Chan S-P, Pakkiri L, Chong J, Liew O-W, Ng T-P, Ling L-H,  Sim D, Leong K-T, Yeo D, Ong H-Y,  Jaufeerally F, Wong R, Chai P, Low A, Davidsson P, Liljeblad M, Söderling A-S, Gan L-M, Bhat R, Purnamawati K, Lam C and Richards M. Thymosin Beta‐4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction (2017) Journal of the American Heart Association, doi.org/10.1161/JAHA.117.005586
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Eriksson E, Milenova I, Wenthe J, Stahle M, Leja-Jarblad J, Ullenhag G, Dimberg A, Moreno R, Alemany R and Loskog A. (2017) Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus. Clinical Cancer Research, Doi: 10.1158/1078-0432.CCR-17-0285
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Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge R, Frånberg M, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Enroth S, Johansson Å, Bosdotter Enroth S, Gustafsson S, Lind L, Lindgren C, Morris A, Giedraitis V, Silveira A, Franco-Cereceda A, Tremoli E, IMPROVE study group , Gyllensten U, Ingelsson E, Brunak S, Eriksson P, Ziemek D, Hamsten A and Mälarstig A. Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. (2017) PLOS Genetics 13(4), doi.org/10.1371/journal.pgen.1006706
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Gerdle B, Ghafouri B, Ghafouri N, Bäckryd E and Gordh T. Signs of ongoing inflammation in female patients with chronic widespread pain. A multivariate, explorative, cross-sectional study of blood samples. (2017) Medicine, http://dx.doi.org/10.1097/MD.0000000000006130
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Harlid S, Myte R and Van Guelpen B. The Metabolic Syndrome, Inflammation, and Colorectal Cancer Risk: An Evaluation of Large Panels of Plasma Protein Markers Using Repeated, Prediagnostic Samples. (2017) Mediators of Inflammation, doi:10.1155/2017/4803156
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Hofmann R, Tornvall P, Witt N, Alfredsson J, Svensson L, Jonasson L and Nilsson L. Supplemental oxygen therapy does not affect the systemic inflammatory response to acute myocardial infarction (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12716
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Kim J, Tomalin L, Lee J, Fitz L, Berstein G, Correa-da Rosa J, Garcet S, Lowes M, Valdez H, Wolk R, Suarez-Farinas M and Krueger J. Reduction of inflammatory and cardiovascular proteins in the blood of psoriasis patients; differential responses between tofacitinib and etanercept after 4 weeks of treatment. (2017) Journal of Investigative Dermatology, doi:10.1016/j.jid.2017.08.040A
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Lakshmikanth T, Olin A, Chen Y, Mikes J, Fredlund E, Remberger M, Omazic B and Brodin P. Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation (2017) Cell Reports, doi.org/10.1016/j.celrep.2017.08.021
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Mahdessian H, Perisic Matic L, Lengquist M, Gertow K, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Tremoli E, Hamsten A, Eriksson P, Hedin U, Mälarstig A, IMPROVE study group. Integrative Studies Implicate Matrix Metalloproteinase 12 as a Culprit Gene for Large-Artery Atherosclerotic Stroke. (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12655
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Mazurkiewicz M, Hillert E-K, Wang X, Pellegrini P, Hägg Olofsson M, Selvaraju K, D’Arcy P and Linder S. Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition. (2017) Oncotarget, doi: 10.18632/oncotarget.15501
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Mohammad M, Noc N, Lang I, Holzer M, Clemmensen P, Jensen U, Metzler B and Erlinge, D. Proteomics in Hypothermia as Adjunctive Therapy in Patients with ST-Segment Elevation Myocardial Infarction: A CHILL-MI Substudy (2017) Therapeutic Hypothermia and Temperature Management, doi.org/10.1089/ther.2016.0041
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Panezai J, Ghaffar A, Altamash M, Sundqvist K-G, Engström P-E and Larsson A. Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. (2017) PLOS ONE, doi.org/10.1371/journal.pone.0188945
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Savola P, Brück O, Olson T, Kelkka T, Kauppi M, Kovanen P, Kytölä S, Sokka-Isler T, Loughran T, Leirisalo-Repo M and Mustjoki S. Somatic STAT3 mutations in the Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia. (2017) Haematologica, doi:10.3324/haematol.2017.175729
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Schiza A, Wenthe J, Mangsbo S, Eriksson E, Nilsson A, Tötterman T, Loskog A and Ulenhag G. Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients. (2017) Journal of Translational Medicine, DOI: 10.1186/s12967-017-1182-z
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Solheim N, Östlund, S, Gordh T and Rosseland L.A. Women report higher pain intensity at a lower level of inflammation after knee surgery compared with men. (2017) Pain Reports, doi: 10.1097/PR9.0000000000000595
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Stensson N, Ghafouri B, Gerdle B and Ghafouri N. Alterations of anti-inflammatory lipids in plasma from women with chronic widespread pain – a case control study (2017) Lipids in Health &  Disease, DOI: 10.1186/s12944-017-0505-7
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Vallejo J,Dunér P, Fredrikson G, Nilsson J and Bengtsson E. Autoantibodies against aldehyde-modified collagen type IV are associated with risk of development of myocardial infarction. (2017) Journal of Internal Medicine, doi/10.1111/joim.12659/full
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Villani A-C, Satija1 R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager P, Rozenblatt-Rosen O, Lane A, Haniffa M, Regev A and Hacohen N. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. (2017) Science, DOI: 10.1126/science.aah4573
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Willeit K, Pechlaner R, Willeit P, Skroblin P, Paulweber B, Schernthaner C, Toell T, Egger G, Weger S, Oberhollenzer M, Kedenko L, Iglseder B, Bonora E, Schett G, Mayr M, Willeit J and Kiechl S. Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation. JAMA Cardiology (2017), doi:10.1001/jamacardio.2017.0064
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Zhang W, Ambikan A, Sperk M, van Domselaar R, Nowak P, Noyan K, Russom A,, Sönnerborg A and Neogi U. Transcriptomics and Targeted Proteomics Analysis to Gain  Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers. (2017) EBioMedicine, doi:10.1016/j.ebiom.2017.11.031
Article link>

2016

Berntson L, Hedlund-Treutiger I and Alving K. Anti-inflammatory effect of exclusive enteral nutrition in patients with juvenile idiopathic arthritis. (2016) Clinical and Experimental Rheumatology, 34(5):941-945
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Carlsson A, Sundström J, Carrero J, Gustafsson S, Stenemo M, Larsson A, Lind L and Ärnlöv J. Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria. (2016) Eur J. Prev. Cardiol., DOI: 10.1177/2047487316676134.
PubMed link>

Eisenberg T. et. al. Cardioprotection and lifespan extension by the natural polyamine spermidine (2016) Nature Medicine, DOI: 10.1038/nm.4222.
PubMed link>

Goncalves I, Edsfeldt A, Colhoun H, Shore A, Palombo C, Natali A, Nordin Fredrikson G, Björbacka H, Wigren M, Bengtsson E, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Gates P, Khan F, Looker H, Adams F, Belch J, Pinnola S, Venturi E, Kozakova M, Gan L, Schnecke C and Nilsson J. Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. (2016) BMC Cardiovascular Disorders, 16:171 DOI 10.1186/s12872-016-0346-8
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Huang B, Svensson P, Ärnlov J, Sundström J, Lind L and Ingelsson E. Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies. (2016) Atherosclerosis, 10.1016/j.atherosclerosis.2016.09.014
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Kaihola H, Yaldir F, Hreinsson J, Hörnaeus K, Bergquist J, Olivier J, Åkerud H and Sundström-Poromaa I. Effects of Fluoxetine on Human Embryo Development. (2016) Frontiers in Cellular Neuroscience, doi: /10.3389/fncel.2016.00160
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Loskog A, Maleka A, Mangsbo S, Svensson E, Lundberg C, Nilsson A, Krause J, Agnarsdottir M, Sundin A, Ahlström H, Tötterman T and Ullenhag G. Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients. British Journal of Cancer (2016) 114, 872–880. doi:10.1038/bjc.2016.42
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Shaw P, Yang Y, Gonzalez J, Kuruvilla S, Gottbrecht M, Epstein F,Gan L, Keeley E, Kramer C, Salerno M. Extracellular volume by CMR is associated with serum biomarkers of extracellular matrix turnover and inflammation in hypertensive heart disease. Journal of Cardiovascular Magnetic Resonance (2016)  doi:10.1186/1532-429X-18-S1-O103
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Westergren H, Svedlund S, Momo R, Blomster J, Wåhlander K, Rehnström E, Greasley P, Regina Fritsche‑Danielson R, Oscarsson J and Gan L-M. Insulin resistance, endothelial function, angiogenic factors and clinical outcome in non‑diabetic patients with chest pain without myocardial perfusion defects. Cardiovasc Diabetol (2016) 15:36 DOI 10.1186
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Jahn L , Lee Hartline, Nagashree Rao, Brent Logan, Justin J Kim, Kevin Aylor , Li-Ming Gan, Helena U Westergren, and Eugene J Barrett. Insulin enhances endothelial function throughout the arterial tree in healthy but not metabolic syndrome subjects. J. Clin. Endocrinol. Metab. (2016) doi: 10.1210/jc.2015-3293
PubMed link >

2015

Helseth R, Weiss T, Opstad T, Siegbahn A, Solheim S, Freynhofer M, Huber K, Arnesen H and Seljeflot S. Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction. Thrombosis Res. (2015), 136: 1240-1244
PubMed link >

Kaudewitz D, Skroblin P, Bender LH, Barwari T, Willeit P, Pechlaner R, Sunderland NP, Willeit K, Morton A, Armstrong PC, Chan MV, Lu R, Yin X, Gracio F, Dudek K, Langley S, Zampetaki A, de Rinaldis E, Ye S, Warner TD, Saxena A, Kiechl S, Storey R, Mayr M. Association of MicroRNAs and YRNAs with Platelet Function. Circ Res. (2015) Feb 5;118(3):420-32. doi: 10.1161/CIRCRESAHA
Pubmed link >

Nowak C, Sundström J, Gustafsson S, Giedraitis V, Lind L, Ingelsson E, Fall T.Protein biomarkers for insulin resistance and type 2 diabetes risk in two large community cohorts. Diabetes. (2015) Sep 29. pii: db150881.
PubMed link >

Pauk M, Grgurevic L, Brkljacic J, Kufner V Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt J, Lin H, Volarevic S and Vukicevic S. Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice (2015) International Orthopaedics, doi: 10.1007/s00264-014-2550-4
PubMed link>

Wigren M, Rattik S, Hultman K, Björkbacka H, Nordin-Fredrikson G, Bengtsson E, Hedblad B, Siegbahn A, Goncalves I, Nilsson J. Decreased levels of stem cell factor in subjects with incident coronary events. J Intern Med. (2015) Oct 14. doi: 10.1111/joim.12443.
PubMed link >


Pathophysiology & patient stratification

2024

Alexandersson A, Venäläinen MS, Heikkilä N, et al. Proteomics screening after pediatric allogenic hematopoietic stem cell transplantation reveals an association between increased expression of inhibitory receptor FCRL6 on γδ T cells and cytomegalovirus reactivation. (2024) Immunology and Cell Biology, DOI: 10.1111/imcb.12762
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Al-Mubarak A, Markousis Mavrogenis G, Guo X,  Biomarker and transcriptomics profiles of serum selenium concentrations in patients with heart failure are associated with immunoregulatory processes. (2024) Redox Biology, DOI: 10.1016/j.redox.2024.103046
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Chen J, Goodrich J, Walker D, et al. Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth. (2024) Environment International, DOI: 10.1016/j.envint.2024.108601
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Christou CN, Sandström K, Regula N, et al. Prognostic value of bone marrow and tumor 18 F-FDG uptake on PET/CT in patients with oropharyngeal cancer and the interplay between inflammation and FDG uptake. (2024) Head & Neck, DOI: 10.1002/hed.27711
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Ducatez F, Tebani A, Abily-Donval L, et al. New insights and potential biomarkers for intraventricular hemorrhage in extremely premature infant, case-control study. (2024) Pediatric Research, DOI: 10.1038/s41390-024-03111-9
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Giunti E, Collu R, Reisman J, et al. Multimodal comparison of plasma proteins associated with blood-brain barrier impairment in Alzheimer’s disease. (2024) Aging Communications, DOI: 10.53388/AGING202406001
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Gustafsson S, Lampa E, Jensevik Eriksson K, et al.  Markers of imminent myocardial infarction. (2024) Nature Cardiovascular Research, DOI: 10.1038/s44161-024-00422-2
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Jauhiainen S, Onyeogaziri FC, Lazzaroni F, et al. Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology. (2024) Biochimica et Biophysica Acta Molecular Basis of Disease, DOI: 10.1016/j.bbadis.2024.167139l
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Kouwenberg CV, Kuiper JJW, de Boer JH, et al. Serum Biomarkers of Vascular Involvement in Childhood Uveitis. (2024) Translational Vision Science & Technology, DOI: 10.1167/tvst.13.4.9
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Lafta MS, Sokolov AV, Landtblom AM, et al. Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls. (2024) European Journal of Pain, DOI: 10.1002/ejp.2231
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Liao J, Goodrich JA, Chen W, et al. Cardiometabolic profiles and proteomics associated with obesity phenotypes in a longitudinal cohort of young adults. (2024) Scientific Reports, DOI: 10.1038/s41598-024-57751-2
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Lindley KJ, Perry A, Jacobs M, et al. Differences in Cardiometabolic Proteins in Pregnancy Prioritize Relevant Targets of Preeclampsia. (2024) Arteriosclerosis, Thrombosis, and Vascular Biology, DOI: 10.1161/ATVBAHA.124.320737
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Luo H, Huemer MT, Petrera A, et al. Association of plasma proteomics with incident coronary heart disease in individuals with and without type 2 diabetes: results from the population-based KORA study. (2024) Cardiovascular Diabetology, DOI: 10.1186/s12933-024-02143-z
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Lyu J, Jiang M, Zhu Z, et al. Identification of biomarkers and potential therapeutic targets for pancreatic cancer by proteomic analysis in two prospective cohorts. (2024) Cell Genomics, DOI: 10.1016/j.xgen.2024.100561
Article link>

Moorlag SJCFM, Folkman L, Ter Horst R, et al. Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity. (2024) Immunity, DOI: 10.1016/j.immuni.2023.12.005
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Muñoz-Barrera L, Perez-Sanchez C, Ortega-Castro R, et al. Personalized cardiovascular risk assessment in Rheumatoid Arthritis patients using circulating molecular profiles and their modulation by TNFi, IL6Ri, and JAKinibs. (2024) Biomedicine & Pharmacotherapy, DOI: 10.1016/j.biopha.2024.116357
Article link>

Ozonoff A, Jayavelu ND, Liu S, et al. Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. (2024) Nature Communications, DOI: 10.1038/s41467-023-44090-5
Article link>

Papier K, Atkins JR, Tong TYN,  et al. Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank. (2024) Nature Communications, DOI: 10.1038/s41467-024-48017-6
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Salvermoser L, Goldberg SN, Alunni-Fabbroni M, et al. CT-guided high dose rate brachytherapy can induce multiple systemic proteins of proliferation and angiogenesis predicting outcome in HCC. (2024) Translational Oncology, DOI: 10.1016/j.tranon.2024.101919
Article link>

Schillemans T, Yan Y, Ribbenstedt A, et al. OMICs Signatures Linking Persistent Organic Pollutants to Cardiovascular Disease in the Swedish Mammography Cohort. (2024) Environmental Science & Technology, DOI: 10.1021/acs.est.3c06388
Article link>

Shah R, Zhong J, Massier L, et al. Targeted Proteomics Reveals Functional Targets for Early Diabetes Susceptibility in Young Adults. (2024) Circulation. Genomic and Precision Medicine, DOI: 10.1161/CIRCGEN.123.004192
Article link>

Trares K, Wiesenfarth M, Stocker H, et al. Addition of inflammation-related biomarkers to the CAIDE model for risk prediction of all-cause dementia, Alzheimer’s disease and vascular dementia in a prospective study (2024) Immunity & Ageing, DOI: 10.1186/s12979-024-00427-2
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Vadadokhau U, Varga I, Káplár M, et al. Examination of the Complex Molecular Landscape in Obesity and Type 2 Diabetes. (2024) International Journal of Molecular Sciences, DOI: 10.3390/ijms25094781
Article link>

van Essen BJ, Tharshana GN, Ouwerkerk W, et al. Distinguishing heart failure with reduced ejection fraction from heart failure with preserved ejection fraction: A phenomics approach. (2024) European Journal of Heart Failure, DOI: 10.1002/ejhf.3156
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Wadström K, Jacobsson LTH, Mohammad AJ, et al. Associations between plasma metabolism associated proteins and future development of giant cell arteritis: results from a prospective study. (2024) Rheumatology,DOI: 10.1093/rheumatology/keae073
Article link>

Wu S, Li Y, Zhao X,  et al. Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders. (2024) Clinical Proteomics, DOI: 10.1186/s12014-024-09480-x
Article link>

Wyss N, Berner F, Walter V, et al. Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade. (2024) American Journal of Respiratory and Critical Care Medicine, DOI: 10.1164/rccm.202311-2136OC
Article link>

Zhao T, Zeng J, Zhang R, et al. Serum Olink Proteomics-Based Identification of Protein Biomarkers Associated with the Immune Response in Ischemic Stroke. (2024) Journal of Proteome Research, DOI: 10.1021/acs.jproteome.3c00885
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Zheng YX, Chen XB, Wang ZY, et al. Efficacy of dupilumab in palmoplantar pustulosis treatment highlights the role of Th2 inflammation. (2024) Allergy, DOI: 10.1111/all.16019
Article link>

2023

Abozaid YJ, Ayada I, van Kleef LA,  et al. Plasma proteomic signature of fatty liver disease: the Rotterdam Study. (2023) Hepatology, DOI: 10.1097/HEP.0000000000000300
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Adamo M, Pagnesi M, Di Pasquale M, et al. Differential biomarker expression in heart failure patients with and without mitral regurgitation: Insights from BIOSTAT-CHF. (2023) International Journal of Cardiology, DOI: 10.1016/j.ijcard.2023.131664
Article link>

Ali EA, Syed A, Khailova L, et al. Novel Biomarkers of Necrotizing Enterocolitis in Neonates Undergoing Congenital Heart Disease Surgery: A Pilot Cohort Study (2023) Journal of the American Heart Association, DOI: 10.1161/JAHA.123.030712
Article link>

Bakhshi H, Michelhaugh SA, Bruce SA, et al. Association between proteomic biomarkers and myocardial fibrosis measured by MRI: the multi-ethnic study of atherosclerosis. (2023) EBioMedicine, DOI: 10.1016/j.ebiom.2023.104490
Article link>

Batra R, Uni R, Akchurin OM, et al. Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. (2023) Molecular Medicine, DOI: 0.1186/s10020-023-00609-6
Article link>

Biesemann N, Margerie D, Asbrand C, et al. Additive efficacy of a bispecific anti-TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis. (2023) Science Translational Medicine, DOI: 10.1126/scitranslmed.abq4419
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Björkander S, Klevebro S, Hernandez-Pacheco N, et al. Obese asthma phenotypes display distinct plasma biomarker profiles. (2023) Clinical & Translational Allergy, DOI: 10.1002/clt2.12238
Article link>

Blaauw M, Cristina dos Santos J, Vadaq N, et al.  Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size. (2023) iScience, DOI: 10.1016/j.isci.2023.106486
Article link>

Celik S, Sadrian J, Grossi M, et al. Extracellular Vesicle-Associated TWEAK Contributes to Vascular Inflammation and Remodeling During Acute Cellular Rejection. (2023) JACC: Basic to Translational Science, DOI: 10.1016/j.jacbts.2022.09.014
Article link>

Chen J, Doyle MF, Fang Y, et al. Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort. (2023) Aging Cell, DOI: 10.1111/acel.13955
Article link>

Christensen TD, Madsen K, Maag E, et al. Protein Signatures and Individual Circulating Proteins, including IL-6 and IL-15, Associated with Prognosis in Patients with Biliary Tract Cancer. (2023) Cancers, DOI: 10.3390/cancers15041062
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Davidsson P, Eketjäll S, Eriksson N, et al. VEGF-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease. (2023) Cardiovascular Research, DOI: 10.1093/cvr/cvad039
Article link>

Diaz-Canestro C, Chen J, Liu Y, et al. A machine-learning algorithm integrating baseline serum proteomic signatures predicts exercise responsiveness in overweight males with prediabetes. (2023) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2023.100944
Article link>

Ehtewish H, Mesleh A, Ponirakis G, et al. Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia. (2023) International Journal of Molecular Sciences, DOI: 10.3390/ijms24098117
Article link>

El-Agnaf O, Bensmail I, Al-Nesf MAY, et al. Uncovering a neurological protein signature for severe COVID-19. (2023) Neurobiology of Disease, DOI: 10.1016/j.nbd.2023.10614710.1016/j.nbd.2023.106147
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Eren F, Schwieler L, Orhan F, et al. Immunological protein profiling of first-episode psychosis patients identifies CSF and blood biomarkers correlating with disease severity. (2023) Brain, Behavior, and Immunity, DOI: 10.1016/j.bbi.2023.04.020
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Ernst MK, Evans ST, Techner JM,  et al. Vitamin D3 and deconvoluting a rash. (2023) JCI Insight, DOI: 10.1172/jci.insight.163789
Article link>

Gijs M, Adelaar TI, Vergouwen DPC, et al. Tear Fluid Inflammatory Proteome Analysis Highlights Similarities Between Keratoconus and Allergic Conjunctivitis. (2023) Investigative Ophthalmology &  Visual Science, DOI: 10.1167/iovs.64.15.9
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Guterstam Y, Acharya G, Schott K, et al. Immune cell profiling of vaginal blood from patients with early pregnancy bleeding. (2023) American Journal of Reproductive Immunology, DOI: 10.1111/aji.13738
Article link>

Han J,  Correa da Rosa J, Agarwal A, et al. Modulation of Inflammatory Proteins in Serum May Reflect Cutaneous Immune Responses in Cancer Immunotherapy. (2023) JID Innovations, DOI: 10.1016/j.xjidi.2022.100179
Article link>

Hepp DH, van Wageningen TA, Kuiper KL, et al. Inflammatory Blood Biomarkers Are Associated with Long-Term Clinical Disease Severity in Parkinson’s Disease. (2023) International Journal of Molecular Sciences, DOI: 10.3390/ijms241914915
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Holmdahl I, Chakraborty S, Hoyer A, et al. Inflammatory related plasma proteins involved in acute preschool wheeze. (2023) Clinical and Translational Allergy, DOI: 10.1002/clt2.12308
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Ju T, Labib A, Nattkemper L, et al. Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis. (2023) Acta Dermato-Venereologica, DOI: 10.2340/actadv.v103.4804
Article link>

Kaiser S, Zhang L, Mollenhauer B,  et al. A proteogenomic view of Parkinson’s disease causality and heterogeneity. (2023) NPJ Parkinson’s Disease, DOI: 10.1038/s41531-023-00461-9
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Kastinen M, Sirniö P, Elomaa H, et al. Immunological and prognostic significance of tumour necrosis in colorectal cancer. (2023) British Journal of Cancer, DOI: 10.1038/s41416-023-02258-2
Article link>

Korhonen L, Paul ER, Wåhlén K, et al. Multivariate analyses of immune markers reveal increases in plasma EN-RAGE in first-episode psychosis patients. (2023) Translational Psychiatry, DOI: 10.1038/s41398-023-02627-8.
Article link>

Kolossváry M, deFilippi C, McCallum S, et al. Identification of pre-infection markers and differential plasma protein expression following SARS-CoV-2 infection in people living with HIV. (2023) EBioMedicine, DOI: 10.1016/j.ebiom.2023.104538
Article link>

Lee B, Jones EK, Manohar M, et al. Distinct serum immune profiles define the spectrum of acute and chronic pancreatitis from the multi-center PROCEED study. (2023) Gastroenterology, DOI: 10.1053/j.gastro.2023.03.236
Article link>

Leibovitzh H, Lee SH, Raygoza Garay JA, et al. Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis. (2023) Gut, DOI: 10.1136/gutjnl-2022-328421
Article link>

Lin K, Wang T, Tang Q, et al. IL18R1-Related Molecules as Biomarkers for Asthma Severity and Prognostic Markers for Idiopathic Pulmonary Fibrosis. (2023) Journal of Proteome Research, DOI: 10.1021/acs.jproteome.3c00389
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Lind L, Titova O, Zeng R, et al. Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation. (2023) Circulation. Genomic and Precision Medicine, DOI: /10.1161/CIRCGEN.123.004233
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Liu J, Chen B, Lu H, et al. Identification of novel candidate biomarkers for acute myocardial infarction by the Olink proteomics platform. (2023) Clinica Chimica Acta, DOI: 10.1016/j.cca.2023.117506
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Liu Z, McCutcheon F, Ho H, et al. Tranexamic acid in a mouse model of cerebral amyloid angiopathy: setting the stage for a novel stroke treatment approach. (2023) Research and Practice in Thrombosis and Haemostasis, DOI: 10.1016/j.rpth.2023.102166
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Llaurador-Coll M, Rios S, García-Gavilán JF, et al. Plasma levels of neurology-related proteins are associated with cognitive performance in an older population with overweight/obesity and metabolic syndrome. (2023) Geroscience, DOI: 10.1007/s11357-023-00764-y
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Lung Cancer Cohort Consortium (LC3) The blood proteome of imminent lung cancer diagnosis. (2023) Nature Communications, DOI: 10.1038/s41467-023-37979-8
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Maple-Grødem J, Ushakova A, Pedersen KF, et al. Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach. (2023) Neurobiology of Disease, DOI: 10.1016/j.nbd.2023.106281
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Mesleh A, Ehtewish H, de la Fuente A, et al. Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study. (2023) International Journal of Molecular Sciences, DOI: 10.3390/ijms24087443
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Mahdi A, Zhao A, Fredengren E, et al. Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 syndrome with and without postural orthostatic tachycardia syndrome: a multi-omic profiling study. (2023) Scientific Reports, DOI: 10.1038/s41598-023-47539-1
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Michaëlsson E, Lund LH, Hage C, et al. Myeloperoxidase Inhibition Reverses Biomarker Profiles Associated With Clinical Outcomes in HFpEF. (2023) JACC. Heart Failure, DOI: 10.1016/j.jchf.2023.03.002
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Mir FA, Abdesselem HB, Cyprian F, et al. Inflammatory protein signatures in individuals with obesity and metabolic syndrome. (2023) Scientific Reports, DOI: 10.1038/s41598-023-49643-8
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Moaddel R, Farmer C, Yavi M, et al. Cerebrospinal fluid exploratory proteomics and ketamine metabolite pharmacokinetics in human volunteers after ketamine infusion. (2023) iScience, DOI: 10.1016/j.isci.2023.108527
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Ni W, Breitner S, Nikolaou N, et al. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. (2023) Environmental Science & Tehnology, DOI: 10.1021/acs.est.3c00302
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Ogulur I, Yazici D, Pat Y, et al. Mechanisms of gut epithelial barrier impairment caused by food emulsifiers polysorbate 20 and polysorbate 80. (2023) Allergy, DOI: 10.1111/all.15825
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Oldham JM, Huang Y, Bose S, et al. Proteomic Biomarkers of Survival in Idiopathic Pulmonary Fibrosis. (2023) American Journal of Respiratory and Critical Care Medicine, DOI: 10.1164/rccm.202301-0117OC
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Oren RL, Kim EJ, Leonard AK, et al. Age-dependent differences and similarities in the plasma proteomic signature of postoperative delirium. (2023) Scientific Reports, DOI: 10.1038/s41598-023-34447-7
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Ouwerkerk W, Belo Pereira JP, Maasland T, et al. Multiomics Analysis Provides Novel Pathways Related to Progression of Heart Failure. (2023) Journal of the American College of Cardiology, DOI: 10.1016/j.jacc.2023.08.053
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Overmars LM, Kuipers S, van Es B, et al. A cluster of blood-based protein biomarkers associated with decreased cerebral blood flow relates to future cardiovascular events in patients with cardiovascular disease. (2023) Journal of Cerebral Blood Flow and Metabolism, DOI: 10.1177/0271678X231195243
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Pallares Robles A, Ten Cate V, Lenz M, et al. Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification. (2023) Thrombosis Research, DOI: 10.1016/j.thromres.2023.04.023
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Peng CC, Sirivolu S, Pike S, et al. Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma. (2023) International Journal of Molecular Science, DOI: 10.3390/ijms24076825
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Perricos A, Husslein H, Kuessel L, et al. Does the Use of the “Proseek® Multiplex Inflammation I Panel” Demonstrate a Difference in Local and Systemic Immune Responses in Endometriosis Patients with or without Deep-Infiltrating Lesions? (2023) International Journal of Molecular Science, DOI: 10.3390/ijms24055022
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Pua CJ, Loo G, Kui M, et al. Impact of Diabetes on Myocardial Fibrosis in Patients With Hypertension: The REMODEL Study. (2023) Circulation: Cardiovascular Imaging, DOI: 10.1161/CIRCIMAGING.123.015051
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Razaghizad A, Aziz H, Zhang GK, et al. Pathophysiological Sex-Differences in Heart Failure Progression after Acute Coronary Syndrome: Insights from the EXAMINE Trial. (2023) Journal of Cardiac Failure, DOI: 10.1016/j.cardfail.2023.10.474
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Rodari MM, Cazals-Hatem D, Uzzan M, et al. Insights into the expanding intestinal phenotypic spectrum of SOCS1 haploinsufficiency and therapeutic options. (2023) Journal of Clinical Immunology, DOI: 10.1007/s10875-023-01495-7
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Schiopu A, Björkbacka H, Narasimhan G, et al. Elevated soluble LOX-1 predicts risk of first-time myocardial infarction. (2023) Annals of Medicine, DOI: 10.1080/07853890.2023.2296552
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Zhao L, Li P, Xu Z, et al. Diagnosis of post-neurosurgical bacterial meningitis in patients with aneurysmal subarachnoid hemorrhage based on the immunity-related proteomics signature of the cerebrospinal fluid. (2023) Frontiers in Neurology, DOI: 10.3389/fneur.2023.1166598
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2022

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Brink M, Berglin E, Mohammad AJ, et al. Protein profiling in pre-symptomatic individuals separates MPO-ANCA and PR3-ANCA vasculitides. (2022) Arthritis & Rheumatology, DOI: 10.1002/art.42425
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Buyukozkan M, Alvarez-Mulett S, et al. Integrative metabolomic and proteomic signatures define clinical outcomes in severe COVID-19. (2022) iScience, DOI: 10.1016/j.isci.2022.104612
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Diorio C, Shraim R, Myers R, et al. Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome Patients with B-Cell ALL Receiving CAR T19. (2022) Clinical Cancer Research, DOI:  doi: 10.1158/1078-0432.CCR-22-0822
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Fernandez N, Perumal D, Rahman A, et al. High dimensional immune profiling of smoldering multiple myeloma distinguishes distinct tumor microenvironments. (2022) Clinical Lymphoma Myeloma and Leukemia, DOI: 10.1016/j.clml.2022.07.001
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Feyaerts D, Hédou J, Gillard J, et al. Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19. (2022) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2022.100680
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Göteson A, Isgren A, Sparding T,  et al. A serum proteomic study of two case-control cohorts identifies novel biomarkers for bipolar disorder. (2022) Translational  Psychiatry, DOI: 10.1038/s41398-022-01819-y
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Mi J, Liu Z, Pei S, et al. Mendelian randomization study for the roles of IL-18 and IL-1 receptor antagonist in the development of inflammatory bowel disease. (2022) International Immunopharmacology, DOI: 10.1016/j.intimp.2022.109020
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Nurmohamed NS, Belo Pereira JP, et al. Targeted proteomics improves cardiovascular risk prediction in secondary prevention. (2022) European Heart Journal, DOI: 10.1093/eurheartj/ehac055
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Oliveras T, Revuelta-López E, García-García C, et al. Circulating virome and inflammatory proteome in patients with ST-elevation myocardial infarction and primary ventricular fibrillation. (2022) Scientific Reports, DOI: 10.1038/s41598-022-12075-x
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Razaghi A, Szakos A, Alouda M, et al. Proteomic Analysis of Pleural Effusions from COVID-19 Deceased Patients: Enhanced Inflammatory Markers. (2022) Diagnostics, 10.3390/diagnostics12112789
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Regan JA, Truby LK, Tahir UA,  et al. Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events. (2022) Scientific Reports, DOI: 10.1038/s41598-022-24226-1
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Sabaa AA, Shen Q, Lennmyr EB, et al. Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls. (2022) New Biotechnoogy, DOI: 10.1016/j.nbt.2022.06.005
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Schmitz T, Harmel E, Heier M, et al. Inflammatory plasma proteins predict short-term mortality in patients with an acute myocardial infarction. (2022) Journal of Translational Medicine, DOI: 10.1186/s12967-022-03644-9
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2021

Cuff S, Merola J, Twohih J, et al. Toll-like receptor linked cytokine profiles in cerebrospinal fluid discriminate neurological infection from sterile inflammation. (2021) Brain Communications, DOI: 10.1093/braincomms/fcaa218
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Herder C, Maalmi H, Strassburger K, et al. Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes. (2021) Diabetes, DOI: 10.2337/db20-1054
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Hjort M, Eggers KM, Lindhagen L, et al. Differences in biomarker concentrations and predictions of long-term outcome in patients with ST-elevation and non-ST-elevation myocardial infarction. (2021) Clinical Biochemistry, DOI: 10.1016/j.clinbiochem.2021.09.001
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Hussain A, Tang O, Sun C, et al. Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (From the Atherosclerosis Risk in Communities Study). (2021) American Journal of Cardiology, DOI: 10.1016/j.amjcard.2021.01.017
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Katz R, Tahir U, Ngo D, et al. Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults. (2021) Circulation, DOI: 10.1161/CIRCGEN.120.003191
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Maglinger B, Sands M, Frank J,  et al. Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity. (2021) Journal of Neuroinflammation, DOI: 10.1186/s12974-021-02157-4
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McKay T, Rhee J, Colon K, et al. Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery. (2021) Journal of Cardiothoracic and Vascular Anesthesia, DOI: 10.1053/j.jvca.2021.05.002
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Monjazeb A,  Giobbie-Hurder A, Lako A, et al. A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-Dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer. (2021) Clinical Cancer Research, DOI: 0.1158/1078-0432.CCR-20-4632
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Schrijver B, Kolijn PM, Ten Berge J, et al. Vitreous proteomics, a gateway to improved understanding and stratification of diverse uveitis aetiologies. (2021) Acta Ophthalmologica, DOI: 10.1111/aos.14993
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Sonnenschein K, Fiedler J, de Gonzalo-Calvo D. et al. Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy. (2021) Scientific Reports, DOI: 10.1038/s41598-020-80868-z
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Ten Cate V, Koeck T, Prochaska J, et al. A targeted proteomics investigation of the obesity paradox in venous thromboembolism. (2021) Blood Advances, DOI: 10.1182/bloodadvances.2020003800
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Truby L, Kwee L, Agarwal R, et al. Proteomic Profiling of Heart Transplant Recipients Identifies CLE4C Expression as a Novel Biomarker of Primary Graft Dysfunction. (2021) The Journal of Heart and Lung Transplantation, DOI: 10.1016/j.healun.2021.01.1859
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van den Broek BTA, Lindemans CA, Boelens JJ, et al. Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses. (2021) Blood Advances, DOI: 10.1182/bloodadvances.2020003824
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Wooley R, Ceelen D, Ouwerkerk W, et al. Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction. (2021) European Journal of Heart Failure, DOI: 10.1002/ejhf.2144
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2020

Ahmed S, Ahmed A, Bouzina H, Lundgren J and Rådegran R. Elevated plasma endocan and BOC in heart failure patients decrease after heart transplantation in association with improved hemodynamics. (2020) Heart and Vessels, DOI: 10.1007/s00380-020-01656-3
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Berbers R, Drylewicz, J, Ellerbroek P,  et al.Authors Targeted Proteomics Reveals Inflammatory Pathways that Classify Immune Dysregulation in Common Variable Immunodeficiency.. (2020) Journal of Clinical Immunology, DOI: 10.1007/s10875-020-00908-1
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Carranza-León D, Oeser A, Marton A, Wang P, Gore J, Titze J, Stein C, Chung C and Ormseth M. Tissue sodium content in patients with systemic lupus erythematosus: association with disease activity and markers of inflammation. (2020) Lupus, DOI: 10.1177/0961203320908934
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Danielson M, Wiklund A, Granath F, Blennow K, Mkrtchian S, Nellgård B, Oras J, Jonsson Fagerlund M, Granström A, Schening A, Rasmussen L, Erlandsson Harris H, Zetterberg H, Zetterberg S-E and Eriksson L. Neuroinflammatory markers associate with cognitive decline after major surgery: findings of an explorative study. (2020) Annals of Neurology, DOI: 10.1002/ana.25678
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Figarska, S, Rigdon, J, Ganna, A, et. al. Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention. (2020) Scientific Reports, DOI: 10.1038/s41598-020-64636-7
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Fraser D, Cepinskas G, Patterson E, et al. Novel Outcome Biomarkers Identified With Targeted Proteomic Analyses of Plasma From Critically Ill Coronavirus Disease 2019 Patients. (2020) Critical Care Explorations, DOI: 10.1097/CCE.0000000000000189
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Ghai V, Fallen S, Baxter D, Scherler K, Kim T-K, Zhou Y, Meabon J, Logsdon A, Banks WA, Schindler A, Cook D, Peskinf E, Lee I and Wang K. Alterations in plasma microRNA and protein levels in war veterans with chronic mild traumatic brain injury. (2020) Journal of Neurotrauma, DOI: 10.1089/neu.2019.6826
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Kuan P-F, Clouston S, Yang X, et. al. Molecular linkage between post-traumatic stress disorder and cognitive impairment: a targeted proteomics study of World Trade Center responders. (2020) Translational Psychiatry, DOI: 10.1038/s41398-020-00958-4
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Molvin J, Jujic A, Melander O, Pareek M, Råstam L, Lindblad U, Daka B, Leosdottir M, Nilsson P, OLsen M and Magnusson M. Exploration of pathophysiological pathways for incident atrial fibrillation using a multiplex proteomic chip. (2020) Openheart, DOI: 10.1136/openhrt-2019-001190
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Moraes L, Magnusson M, Mavroudis G, Polster A, Jonefjäll B, Törnblom H, Sundin J, Simrén M, Strid H and Öhman P. Systemic Inflammatory Protein Profiles Distinguish Irritable Bowel Syndrome (IBS) and Ulcerative Colitis, Irrespective of Inflammation or IBS-Like Symptoms. (2020) Inflammatory Bowel Diseases, DOI: 10.1093/ibd/izz322
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Söderlund S, Persson I, Ilander M, Guilhot J, Hjorth-Hansen H, Koskenvesa P, Richter J, Saussele S, Mustjoki S and Olsson-Strömberg U. Plasma proteomics of biomarkers for inflammation or cancer cannot predict relapse in chronic myeloid leukaemia patients stopping tyrosine kinase inhibitor therapy. (2020) Leukemia Research, DOI: 10.1016/j.leukres.2020.106310
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Wu S, Noren Hooten N, Freeman, et. al. Extracellular vesicles in diabetes mellitus induce alterations in endothelial cell morphology and migration. (2020) Journal of Translational Medicine, DOI: 10.1186/s12967-020-02398-6
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2019

Beijer K, Nowak C, Sundström J, Ärnlöv J, Fall T and Lind L. In search of causal pathways in diabetes: a study using proteomics and genotyping data from a cross-sectional study. (2019) Diabetologia, doi: 10.1007/s00125-019-4960-8
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Brunner P, He H, Pavel A, Czarnowicki T, Lefferdink R, Erickson T, Canter T, Puar N, Rangel S, Malik K, Estrada Y, Krueger J, Guttman-Yassky E and Paller A. The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult, longstanding disease.  (2019) Journal of the American Academy of Dermatology, doi: 10.1016/j.jaad.2019.04.036
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Ek, M, Roth B, Engström G and Ohlsson B. AXIN1 in Plasma or Serum Is a Potential New Biomarker for Endometriosis. (2019) Int. J. Mol. Sci., doi.org/10.3390/ijms20010189
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Erkan EP, Ströbel T, Dorfer C, et al. Circulating Tumor Biomarkers in Meningiomas Reveal a Signature of Equilibrium Between Tumor Growth and Immune Modulation.. (2019) Frontiers in Oncology, DOI: 10.3389/fonc.2019.01031
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Finkernagel F, Reinartz S, Schuldner M, Malz A, Jansen J, Wagner M, Worzfeld T, Graumann J, von Strandmann EP and Müller R. Dual-platform affinity proteomics identifies links between the recurrence of ovarian carcinoma and proteins released into the tumor microenvironment. (2019) Theranostics, DOI: 10.7150/thno.37549
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Gonçalves I, Singh P, Tengryd C, Cavalera M, Yao Mattisson I, Nitulescu M, Flor Person A, Volkov P, Engström G,Orho-Melander M, Nilsson J and Edsfeldt A. (2019) sTRAIL-R2 (Soluble TNF [Tumor Necrosis Factor]-Related Apoptosis-Inducing Ligand Receptor 2) a Marker of Plaque Cell Apoptosis and Cardiovascular Events. Stroke, doi: 10.1161/STROKEAHA.119.024379
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Graumann J, Finkernagel F, Reinartz S, Stief T, Brödje D, Renz H, Jansen J, Wagner U, Worzfeld T, Pogge von Strandmann E and Mülle R. Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Immune Suppression in Ovarian Cancer Plasma. (2019) Frontiers in Oncology, DOI: 10.3389/fonc.2019.01150
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Hysing E-H, Smith L, Thulin M, Karlsten R, Bothelius K and Gordh T. Detection of systemic inflammation in severely impaired chronic pain patients and effects of a multimodal pain rehabilitation program. (2019) Scandinavian Journal of Pain, DOI: 10.1515/sjpain-2018-0340
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Jabbari E, Woodside J, Guo T, Magdalinou N, Chelban V, Athauda D, Lees A, Foltynie T, Houlden H, Church A, Hu M, Rowe J, Zetterberg H and Morris H. Proximity extension assay testing reveals novel diagnostic biomarkers of atypical parkinsonian syndromes (2019) J Neurol Neurosurg Psychiatry, doi: 10.1136/jnnp-2018-320151
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Niewczas M, Pavkov M, Skupien J, Smiles A, Dom Z, Wilson J, Park J, Nair V, Schlafly A, Saulnier P-J, Satake E, Simeone C, Shah H, Qiu C, Looker H, Fiorina P, Ware C, Sun J, Doria A, Kretzler M, Susztak K, Duffin K, Nelson R and Krolewski A. A Signature of Circulating Inflammatory Proteins Enriched for TNF Receptor Superfamily and High Risk of ESRD in Diabetes.  (2019) Nature Medicine, doi.org/10.1038/s41591-019-0415-5
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Pavel A, Zjou L, Diaz A, Ungar B, Dan J, He H, Estrada Y, Xu H, Fernades M, Renert-Yuval, Krueger J and Guttman-Yassky E. The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature (2019) Journal of the American Association of Dermatology, doi: 10.1016/j.jaad.2019.10.039
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Stattin K, Lind L, Elmsta S, Wolk A, Warensjö E, Melhus H, Michaëlsson K and Byberg L. Physical activity is associated with a large number of cardiovascular-specific proteins: Cross-sectional analyses in two independent cohorts (2019) Eur. J. Prevent. Cardiology, doi: 10.1177/2047487319868033
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Tsolakis N, Nordvall L, Janson C, Rydell N, Malinovschi A and Alving K. Characterization of a subgroup of non-type 2 asthma with cow’s milk hypersensitivity in young subjects. (2019) Clinical and Translational Allergy, doi.org/10.1186/s13601-019-0250-2
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Ziegler D, Strom A, Bönhof G, Kannenberg J, Heier M, Rathman W, Peters A, Meisinger C, Roden M, Thorand B and Herder C. Deficits in systemic biomarkers of neuroinflammation and growth factors promoting nerve regeneration in patients with type 2 diabetes and polyneuropathy. (2019) BMJ Open Diabetes Research & Care. DOI: 10.1136/bmjdrc-2019-000752
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2018

Camargo MC, Sivins A, Isajevs S, Folkmanis V, Rudzite D, Gulley M, Offerhaus J, Leja M and Rabkin C. Associations of Epstein-Barr Virus-Positive Gastric
Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response.
(2018) Cancers, doi:10.3390/cancers10090284
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Csösz E, Tóth N, Deák, E, Csutak A and Tözsér J. Wound-Healing Markers Revealed by Proximity Extension Assay in Tears of Patients following Glaucoma Surgery. (2018) Int. J. Mol. Sci, doi:10.3390/ijms19124096
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Figarska S, Gustafsson S, Sundström J, Ärnlöv J, Mälarstig A, Elmståhl S, Fall T, Lind L and Ingelsson E. Associations of Circulating Protein Levels With Lipid
Fractions in the General Population
(2018) Arteriosclerosis, Thrombosis, and Vascular Biology, doi:/10.1161/ATVBAHA.118.311440
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Qian J, Tikk K, Weigl K, Balavarca Y and Brenner H. Fibroblast growth factor 21 as a circulating biomarker at various stages of colorectal carcinogenesis. (2018) British Journal of Cancer, doi.org/10.1038/s41416-018-0280-x
Article link>

Ramqvist T, Näsman A, Franzén B, Bersani C, Alexeyenko A, Becker S, Haeggblom L, Kolev A, Dalianis T and Munck-Wikland E. Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome. (2018) Int. J. Mol. Sciences, doi:10.3390/ijms19040978
Article link>

Söderholm M and Engström G. Fibroblast Growth Factor 23 and Incidence of Subarachnoid Hemorrhage. (2018) Stroke, DOI: 10.1161/STROKEAHA.115.010565.
Article link>

Tewari S, Renney G, Brewin J, Gardner K, Kirkham F, Inusa B, Barrett J, Menzel S, Thein S-L, Ward M and Rees D. Proteomic Analysis Of Plasma From Children With Sickle Cell Anemia And Silent Cerebral Infarction (2018) Haematolgica, Doi:10.3324/haematol.2018.187815
Article link>

2017

Borné Y, Gränsbo K, Nilsson J, Melander O, Orho-Melander M, Smith G and Engström G. Vascular Endothelial Growth Factor D, Pulmonary Congestion, and Incidence of Heart Failure. (2018) JACC, doi.org/10.1016/j.jacc.2017.11.058
Article link>

Bäckryd E, Tanum L, Lind A-L, Larsson A and Gordh T. Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. (2017) Journal of Pain Research, https://doi.org/10.2147/JPR.S128508
Article link>

Gohar A, Gonçalves I, Vrijenhoek J, Haitjema S, van Koeverden I, Nilsson J, de Borst G, de Vries J-P, Pasterkamp G, den Ruijter H, Björkbacka H and de Jager S. Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis (2017) International Journal of Cardiology, http://dx.doi.org/10.1016/j.ijcard.2017.03.101
Article link>

Hage C, Michaëlsson E, Linde C, Donal E, Daubert J-C, Gan L-M and Lund L. Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction. (2017) Circulation: Cardiovascular Genetics, doi.org/10.1161/CIRCGENETICS.116.001633
Article link>

Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum J, Alexander V, Willeit J, Kiech S and Mayr M. Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III (2017) Journal of the American College of Cardiology, Vol 69 (7) DOI: 10.1016/j.jacc.2016.11.065 (Online Appendix)
Article link >

Molin C, Westerberg E and Rostedt Punga A. Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients (2017) Scientific Reports, doi:10.1038/srep39716.
Article link>

Stenemo M, Nowak C, Byberg L, Sundström J, Giedraitis V, Lind L, Ingelsson E, Fall T and Ärnlöv J. Circulating proteins as predictors of incident heart failure in the elderly (2017) European Journal of Heart Failure, doi: 10.1002/ejhf.980
Article link>

Uderhardt S, Ackermann J, Fillep T, Hammond V, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner K, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz‑Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins P, Schabbauer G, Mackman N, Voehringer D, Nadler J, Lee J, Massberg S, Rauh M, Kiechl S, Schett G, O’Donnell V and Krönke G. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. JEM (2017), doi.org/10.1084/jem.20161070
Article link>

Yao Mattisson I, Björkbacka H, Wigren H, Edsfeldt A, Melander O, Nordin Fredrikson G, Bengtsson E, Gonçalves I, Orho-Melander M, Engström G, Almgren P and Nilsson J. Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease. (2017) EBioMedicine, doi.org/10.1016/j.ebiom.2017.11.023
Article link>

2016

Schiopu A, Bengtsson E, Goncalves I, Nilsson J, Nordin Fredrikson G and Björbacka H. Associations Between Macrophage Colony-Stimulating Factor and Monocyte Chemotactic Protein 1 in Plasma and First-Time Coronary Events: A Nested Case–Control Study. (2016) J. Am Heart Assoc., 10.1161/JAHA.115.002851
Article link>

Lind L, Sundström J, Stenmo M, Hagström E and Ärnlöv J. Discovery of new biomarkers for atrial fibrillation using a custom-made proteomics chip. (2016) Heart, 10.1136/heartjnl-2016-309764
Article link>

Schneiderova P, Pika T, Gajdos P, Fillerova R, Kromer P, Kudelka M, Minarik J, Papajik T, Scudla V and Kriegova E. Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma. (2016) Oncotarget.
Article link >


Patient stratification

2024

Broberg O, Feldreich T, Weismann CG, et al. Circulating leptin is associated with adverse vascular changes in young adult survivors of childhood cancer. (2024) Cardiology in the Young, DOI: 10.1017/S1047951124000076
Article link>

Budnik B, Amirkhani H, Forouzanfar MH, et al. Novel proteomics-based plasma test for early detection of multiple cancers in the general population. (2024) BMJ Oncology, DOI: 10.1136/bmjonc-2023-000073
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Callbo PN, Junus K, Gabrysch K, et al. Novel Associations Between Mid-Pregnancy Cardiovascular Biomarkers and Preeclampsia: An Explorative Nested Case-Control Study. (2024) Reproductive Sciences, DOI: 10.1007/s43032-023-01445-z
Article link

Cetrelli L, Lundestad A, Gil EG, et al. Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis-an explorative cross-sectional study. (2024) Pediatric Rheumatology, DOI: 10.1186/s12969-024-00972-6
Article link>

Cîrciumaru A, Kisten Y, Hansson M, et al. Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis-a prospective cohort study. (2024) Rheumatology, DOI: 10.1093/rheumatology/keae146
Article link>

Costello E, Goodrich JA, Patterson WB, et al. Proteomic and Metabolomic Signatures of Diet Quality in Young Adults. (2024) Nutrients, DOI: 10.3390/nu16030429
Article link>

Dalsgaard R, Clemmensen T, Eiskjær H, et al. Proteomics early after heart transplantation and relation to coronary intimal changes and prognosis – an exploratory study. (2024) JHLT Open, DOI: 10.1016/j.jhlto.2024.100110
Article link>

Dregoesc M, Tercan H, Țigu A, et al. Clonal hematopoiesis is associated with cardiovascular events in patients with stable coronary artery disease (2024) iScience, DOI: 10.1016/j.isci.2024.109472
Article link>

Esberg A, Kindstedt E, Isehed C, et al. LIGHT protein: A novel gingival crevicular fluid biomarker associated with increased probing depth after periodontal surgery. (2024) Journal of Clinical Periodontology, DOI: 10.1111/jcpe.13964
Article link>

Fredriksson T, Brudin L, Henningsson AJ, et al. Diagnostic patterns of serum inflammatory protein markers in children with Lyme neuroborreliosis. (2024) Ticks and tTck-Borne Diseases, DOI: 10.1016/j.ttbdis.2024.102349
Article link>

Giannakoulis VG, Schenck EJ, Papoutsi E, et al. Early Mortality in Clinical Trials of Acute Respiratory Distress Syndrome. (2024) American Journal of Respiratory and Critical Care Medicine, DOI: 10.1164/rccm.202402-0318LE
Article link>

Feng T, Jie M, Deng K, et al. Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer. (2024) Clinica Chimica Acta, DOI: 10.1016/j.cca.2024.119675
Article link>

Flora C, Olesnavich M, Zuo Y, et al. Longitudinal plasma proteomics in CAR-T cell therapy patients implicates neutrophils and NETosis in the genesis of CRS. (2024) Blood Advances. DOI: 10.1182/bloodadvances.2023010728
Article link>

Gao M, Wu X, Jiao X, et al. Prognostic and predictive value of angiogenesis-associated serum proteins for immunotherapy in esophageal cancer. (2024) Journal for Immunotherapy of Cancer, DOI: 10.1136/jitc-2022-006616
Article link>

Guo H, Liang M, Chen S, et al. Vitreous Olink Proteomics Reveals Inflammatory Biomarkers for Diagnosis and Prognosis of Traumatic Proliferative Vitreoretinopathy. (2024) Frontiers in Immunology, DOI: 10.3389/fimmu.2024.1355314l
Article link>

Gross CC, Schulte-Mecklenbeck A, Steinberg OV, et al. Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories. (2024) Science Translational Medicine, DOI: 10.1126/scitranslmed.ade8560
Article link>

Guldvik IJ, Ramberg H, Kristensen G, et al. Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy. (2024) World Journal of Urology, DOI: 10.1007/s00345-024-04787-8
Article link>

Guo Y, You J, Zhang Y, et al. Plasma proteomic profiles predict future dementia in healthy adults. (2024) Nature Aging, DOI: 10.1038/s43587-023-00565-0.
Article link>

Gurung RL, Liu S, Liu JJ, et al. Association of plasma angiogenin with risk of major cardiovascular events in type 2 diabetes. (2024) Cardiovascular Diabetology, DOI: 10.1186/s12933-024-02156-8
Article link>

Harrington J, McCrary AW, Nguyen M, et al. Proteomics discovery in children and young adults with HIV identifies fibrosis, inflammatory, and immune biomarkers associated with myocardial impairment. (2024) AIDS, DOI: 10.1097/QAD.0000000000003879
Article link>

Hong J, Eun JW, Baek GO, et al. Multiomics profiling of buffy coat and plasma unveils etiology-specific signatures in hepatocellular carcinoma. (2024) Clinical and Molecular Hepatology, DOI: 10.3350/cmh.2024.0042
Article link>

Horati H, Margaroli C, Chandler JD, et al. Key inflammatory markers in bronchoalveolar lavage predict bronchiectasis progression in young children with CF. (2024) Journal of Cystic Fibrosis, DOI: 10.1016/j.jcf.2024.01.002
Article link>

Huang Y, Ma SF, Oldham JM, et al. Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease. (2024) American Journal of Respiratory and Critical Care Medicine, DOI: 10.1164/rccm.202309-1692OC
Article link>

Jackson S, Lex M, De Wyngard V, et al. Statin use is not associated with inflammation among Chilean women of Mapuche and non-Mapuche ancestry with gallstones. (2024) Future Science, DOI: 10.2144/fsoa-2023-0032
Article link>

Jacobs BM, Vickaryous N, Giovannoni G, et al. Plasma proteomic profiles of UK Biobank participants with multiple sclerosis. (2024) Annals of Clinical and Translational Neurology, DOI: 10.1002/acn3.51990
Article link>

Jakimovski D, Qureshi F, Ramanathan M, et al. Glial cell injury and atrophied lesion volume as measures of chronic multiple sclerosis inflammation. (2024) Journal of the Neurological Sciences, DOI: 10.1016/j.jns.2024.123055
Article link>

Jalaleddini K, Jakimovski D, Keshavan A, et al. Proteomic signatures of physical, cognitive, and imaging outcomes in multiple sclerosis. (2024) Annals of Clinical and Translational Neurology, DOI: 10.1002/acn3.51996
Article link>

Jiang Y, Uhm H, Ip FC, et al. A blood-based multi-pathway biomarker assay for early detection and staging of Alzheimer’s disease across ethnic groups. (2024) Alzheimer’s & Dementia, DOI: 10.1002/alz.13676
Article link>

Jujić A, Molvin J, Holm Isholth H, et al. Association between low selenoprotein P concentrations and anaemia in hospitalized heart failure patients. (2024) ESC Heart Failure, DOI: 10.1002/ehf2.14651
Article link>

Karihtala P, Leivonen SK, Puistola U, et al. Serum protein profiling reveals an inflammation signature as a predictor of early breast cancer survival. (2024) Breast Cancer Research, DOI: 10.1186/s13058-024-01812-x
Article link>

Kobayashi M, Ferreira JP, Kevin D, et al. Proteomic profiles of left atrial volume and its influence on response to spironolactone: Findings from the HOMAGE trial and STANISLAS cohort. (2024) European Journal of Heart Failure, DOI: 10.1002/ejhf.3202
Article link>

Kong T, Qu Y, Zhao T, et al. Identification of novel protein biomarkers from the blood and urine for the early diagnosis of bladder cancer via proximity extension analysis. (2024) Journal of Translational Medicine, DOI: 10.1186/s12967-024-04951-z
Article link>

Lastra Romero A, Seitz T, Zisiadis GA, et al. EDA2R reflects the acute brain response to cranial irradiation in liquid biopsies. (2024) Neuro-Oncology, DOI: 10.1093/neuonc/noae077
Article link>

Leierer J, Salib M, Evgeniou M, et al. Identification of endophenotypes supporting outcome prediction in hemodialysis patients based on mechanistic markers of statin treatment. (2024) Heliyon, DOI: 10.1016/j.heliyon.2024.e30709
Article link>

Li X, Zhou X, Ping X, et al. Combined Plasma Olink Proteomics and Transcriptomics Identifies CXCL1 and TNFRSF12A as Potential Predictive and Diagnostic Inflammatory Markers for Acute Kidney Injury. (2024) Inflammation, DOI: 10.1007/s10753-024-01993-9
Article link>

Li Y, Tang C, Vanarsa K, et al. Proximity extension assay proteomics and renal single cell transcriptomics uncover novel urinary biomarkers for active lupus nephritis. (2024) Journal of Autoimmunity, DOI: 10.1016/j.jaut.2023.103165
Article link>

Li ZM, Liu W, Chen XL, et al. Construction and validation of classification models for predicting the response to concurrent chemo-radiotherapy of patients with esophageal squamous cell carcinoma based on multi-omics data. (2024) Clinics and Research in Hepatology and Gastroenterology, DOI: 10.1016/j.clinre.2024.102318
Article link>

Lozano-Vicario L, Muñoz-Vázquez ÁJ, Ramírez-Vélez R, et al. Association of postoperative delirium with serum and cerebrospinal fluid proteomic profiles: a prospective cohort study in older hip fracture patients. (2024) GeroScience, DOI: 10.1007/s11357-024-01071-w
Article link>

Møller PL, Rohde PD, Dahl JN, et al. Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease. (2024) Genome Medicine, DOI: 10.1186/s13073-024-01313-8
Article link>

Nielsen RL, Monfeuga T, Kitchen RR, et al. Data-driven identification of predictive risk biomarkers for subgroups of osteoarthritis using interpretable machine learning. (2024) Nature Communications, DOI: 10.1038/s41467-024-46663-4
Article link>

Niida T, Yuki H, Suzuki K, et al. Proteomics associated with coronary high-risk plaques by optical coherence tomography. (2024) Journal of Thrombosis and Thrombolysis, DOI: 10.1007/s11239-023-02938-z
Article link>

Nilius H, Hamzeh-Cognasse H, Hastings J, et al. Proteomic profiling for biomarker discovery in heparin-induced thrombocytopenia. (2024) Blood Advances, DOI: 10.1182/bloodadvances.2024012782
Article link>

Panova-Noeva M, Koeck T, Schoelch C, et al. Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study. (2024) Obesity, DOI: 10.1002/oby.24014
Article link>

Parra ER, Zhang J, Duose DY, et al. Multi-omics analysis reveals immune features associated with immunotherapy benefit in squamous cell lung cancer patients from Phase III Lung-MAP S1400I trial. (2024) Clinical Cancer Research, DOI: 10.1158/1078-0432.CCR-23-0251
Article link>

Pase MP, Himali JJ, Puerta R, et al. Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. (2024) Neurology, DOI: 10.1212/WNL.0000000000208075
Article link>

Patel MA, Fraser DD, Daley M, et al. The plasma proteome differentiates the multisystem inflammatory syndrome in children (MIS-C) from children with SARS-CoV-2 negative sepsis. (2024) Molecular Medicine, DOI: 10.1186/s10020-024-00806-x
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Pu X, Lin G, Xiao M, et al. Camrelizumab combined with apatinib and nanoparticle albumin-bound paclitaxel in lung adenocarcinoma (CAPAP-lung): a single-arm phase II study. (2024) eClinicalMedicine, DOI: org/10.1016/j.eclinm.2023.102403
Article link>

Pugashetti JV, Kim JS, Combs MP, et al. A Multi-dimensional Classifier to Support Lung Transplant Referral in Patients with Pulmonary Fibrosis. (2024) The Journal of Heart and Lung Transplantation, DOI: 10.1016/j.healun.2024.03.018
Article link>

Ramakrishnan G, Young MK, Nayak U, et al. Systemic neutrophil degranulation and emergency granulopoiesis in patients with Clostridioides difficile infection. (2024) Anaerobe, DOI: 10.1016/j.anaerobe.2024.102840
Article link>

Royer P, Björnson E, Adiels M, et al. Plasma proteomics for prediction of subclinical coronary artery calcifications in primary prevention. (2024) American Heart Journal, DOI: 10.1016/j.ahj.2024.01.011
Article link>

Royer P, Björnson E, Adiels M, et al. Large-scale plasma proteomics in the UK Biobank modestly improves prediction of major cardiovascular events in a population without previous cardiovascular disease. (2024) European Journal of Preventive Cardiology, DOI: 10.1093/eurjpc/zwae124
Article link>

Rutledge J, Lehallier B, Zarifkar P,  et al. Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease. (2024) Acta Neuropathologica, DOI: 10.1007/s00401-024-02706-0
Article link>

Rydell E, Jacobsson LTH, Turesson C, et al. Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis. (2024) The Journal of Rheumatology, DOI: 10.3899/jrheum.2023-1078
Article link>

Salzinger B, Lundwall K, Evans M, et al. Associations between inflammatory and angiogenic proteomic biomarkers, and cardiovascular events and mortality in relation to kidney function. (2024) Clinical Kidney Journal, DOI: 10.1093/ckj/sfae050
Article link>

Schiff HF, Walker NF, Ugarte-Gil C, et al. Integrated plasma proteomics identifies tuberculosis-specific diagnostic biomarkers. (2024) JCI Insight, DOI: 10.1172/jci.insight.173273
Article link

Schmitz T, Freuer D, Goßlau Y, et al. Can inflammatory plasma proteins predict Long COVID or Fatigue severity after SARS-CoV-2 infection? (2024) Virus Research, DOI: 10.1016/j.virusres.2024.199363
Article link>

Schnorr I, Siegl A, Luckhardt S, et al. Inflammatory biotype of ADHD is linked to chronic stress: a data-driven analysis of the inflammatory proteome. (2024) Translational Psychiatry, DOI: 10.1038/s41398-023-02729-3
Article link>

Shahlaee A, Yang D, Chen J, et al. Vitreous Biomarkers for Proliferative Vitreoretinopathy Prognostication in Patients Undergoing Primary Retinal Detachment Repair. (2024) Translational Vision Science & Technology, DOI: 10.1167/tvst.13.1.3
Article link>

Shelbaya K, Arthur V, Yang Y, et al. Large-Scale Proteomics Identifies Novel Biomarkers and Circulating Risk Factors for Aortic Stenosis. (2024) Journal of the American College of Cardiology, DOI: 10.1016/j.jacc.2023.11.021
Article link>

Shue F, White LJ, Hendrix R, et al. CSF biomarkers of immune activation and Alzheimer’s disease for predicting cognitive impairment risk in the elderly. (2024) Science Advances, DOI: 10.1126/sciadv.adk3674
Article link

Svensson T, Svensson AK, Kitlinski M, et al. Very short sleep duration reveals a proteomic fingerprint that is selectively associated with incident diabetes mellitus but not with incident coronary heart disease: a cohort study. (2024) BMC Medicine, DOI: 10.1186/s12916-024-03392-1
Article link>

Tran D, Beeler JS, Liu J, et al. Plasma Proteomic Signature Predicts Myeloid Neoplasm Risk. (2024) Clinical Cancer Research, DOI: 10.1158/1078-0432.CCR-23-3468
Article link>

van Eijck CWF, Sabroso-Lasa S, Strijk GJ, et al. A liquid biomarker signature of inflammatory proteins accurately predicts early pancreatic cancer progression during FOLFIRINOX chemotherapy. (2024) Neoplasia, DOI: 10.1016/j.neo.2024.100975
Article link>

Vanmaele A, Bouwens E, Hoeks SE, et al. Targeted proteomics and metabolomics for biomarker discovery in abdominal aortic aneurysm and post-EVAR sac volume. (2024) Clinica Chimica Acta, DOI: 10.1016/j.cca.2024.117786
Article link>

Vasudevan Nampoothiri R, Avery L, Pasic I, et al. Multiplex proteomics in the identification of potential biomarkers of very severe sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) in allogeneic hematopoietic cell transplant patients treated with defibrotide. (2024) Acta Haematologica, DOI: 10.1159/000535706
Article link>

Villikudathil AT, Mc Guigan DH, English A, et al.  Exploring metformin monotherapy response in Type-2 diabetes: Computational insights through clinical, genomic, and proteomic markers using machine learning algorithms. (2024) Computers in Biology and Medicine, DOI: 10.1016/j.compbiomed.2024.108106
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Xu F, Su Y, Wang X, et al. Olink proteomics analysis uncovers inflammatory proteins in patients with different states of bipolar disorder. (2024) International Immunopharmacology, DOI: 10.1016/j.intimp.2024.111816
Article link>

Xu Q, Guo D, Shi M, et al. Genetically Determined Plasma Hepatocyte Growth Factor Levels Are Associated With the Risk and Prognosis of Ischemic Stroke. (2024) Stroke, DOI: 10.1161/STROKEAHA.123.045430
Article link>

Zhang X, Li J, Yang L, et al. Targeted proteomics-determined multi-biomarker profiles developed classifier for prognosis and immunotherapy responses of advanced cervical cancer. (2024) Frontiers in Immunology, DOI:  10.3389/fimmu.2024.1391524
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Zhang X, Zhao L, Ngo LH, et al. Pre-diagnostic plasma proteomics profile for hepatocellular carcinoma. (2024) Journal of the National Cancer Institute, DOI: 10.1093/jnci/djae079
Article link>

Zhang Y, Li L, Liu Y, et al. Identification of CCL20 as a prognostic predictor for severe fever with thrombocytopenia syndrome based on plasma proteomics. (2024) The Journal of Infectious Diseases, DOI: 10.1093/infdis/jiae039
Article link>

Zingg F, Ryser FS, Gloor AD, et al. Serum protein profiling reveals distinct patient clusters in giant cell arteritis. (2024) Rheumatology, DOI: 10.1093/rheumatology/keae072
Article link>

Zhou J, Li X, Wang X, et al. Levels of neuronal pentraxin 2 in plasma is associated with cognitive function in patients with schizophrenia. (2024) Psychopharmacology, DOI: 10.1007/s00213-023-06515-3
Article link>

2023

Ahmed A, Kania K, Abdul Rahim H, et al. Adrenomedullin peptides and precursor levels in relation to haemodynamics and prognosis after heart transplantation. (2023) ESC Heart Failure, DOI: 10.1002/ehf2.14399
Article link>

Akel S, Banote RK, Asztely F, et al. Protein profiling in plasma for biomarkers of seizure. (2023) Epilepsy Research, DOI: 10.1016/j.eplepsyres.2023.107241
Article link>

Åkesson J, Hojjati S, Hellberg S, et al. Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis. (2023) Nature Communications, DOI: 10.1038/s41467-023-42682-9
Article link>

Álvez MB, Edfors F, von Feilitzen K, et al. Next generation pan-cancer blood proteome profiling using proximity extension assay. (2023) Nature Communications, DOI: 10.1038/s41467-023-39765-y
Article link>

Angerfors A, Brännmark C, Lagging C, et al. Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome. (2023) Journal of Neuroinflammation, DOI: 10.1186/s12974-023-02912-9
Article link>

Arvidsson M, Ahmed A, Säleby J, et al. Plasma TRAIL and ANXA1 in diagnosis and prognostication of pulmonary arterial hypertension. (2023) Pulmonary Circulation, DOI: 10.1002/pul2.12269
Article link>

Aslam I, Zafar H, Majeed F, et al. Heart failure prediction through proteomic profiling among elderly patients. (2023) NeuroQuantology, DOI: 10.48047/nq.2023.21.6.NQ23080
Article link>

Baidildinova G, Pallares Robles A, et al. Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease.. (2023) Thrombosis Research, DOI: 10.1016/j.thromres.2023.08.017
Article link>

Bao X-H, Chen B-F, Liu J, et al. Olink proteomics profiling platform reveals non-invasive inflammatory related protein biomarkers in autism spectrum disorder. (2023) Frontiers in Molecular Neuroscience, DOI: 10.3389/fnmol.2023.1185021
Article link>

Barak O, Lovelace T, Piekos S, et al. Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes. (2023) BMC Medicine, DOI: 10.1186/s12916-023-03054-8
Article link>

Barbarroja N, López-Montilla M, Cuesta-López L, et al. Characterization of the inflammatory proteome of synovial fluid from patients with psoriatic arthritis: Potential treatment targets. (2023) Frontiers in Immunology, DOI: 10.3389/fimmu.2023.1133435
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Baumhove L, Bomer N, Tromp J, et al. Clinical characteristics and prognosis of patients with heart failure and high concentrations of interleukin-17D. (2023) International Journal of Cardiology, DOI: 10.1016/j.ijcard.2023.131384
Article link>

Beaudin M, Kamali T, Tang W, et al. Cerebrospinal Fluid Proteomic Changes after Nusinersen in Patients with Spinal Muscular Atrophy. (2023) Journal of Clinical Medicine, DOI: 10.3390/jcm12206696
Article link>

Bessede A, Peyraud F, Besse B, et al. TROP2 is associated with primary resistance to immune checkpoint inhibition in patients with advanced non-small cell lung cancer. (2023) Clinical Cancer Research, DOI: 10.1158/1078-0432.CCR-23-2566
Article link>

Bidoki NH, Zera KA, Nassar H, et al. Machine learning models of plasma proteomic data predict mood in chronic stroke and tie it to aberrant peripheral immune responses. (2023) Brain, behavior, and Immunity, DOI: /10.1016/j.bbi.2023.08.002
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Bouwens E, Vanmaele A, Hoeks SE, et al. Circulating biomarkers of cardiovascular disease are related to aneurysm volume in abdominal aortic aneurysm. (2023) Vascular Medicine, DOI: 10.1177/1358863X231181159
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