Olink

Olink®
Part of Thermo Fisher Scientific

Olink Olink Focus
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Custom panels with any biomarker from our comprehensive library

OlinkOlink® Focus

Take the step from early protein biomarker discovery to validation and implementation of clinically relevant protein signatures.

Implement your protein signature

Take the actionable insights gained from protein biomarker discovery and implement them as well-defined protein signatures. Olink Focus is a custom-made product developed by our in-house research and development experts that empowers biomarker utility.

Overview

  • Proteins

    Up to 21 With proven specificity

  • Sample

    1 µL Plasma, serum & more

  • Protein library

    5,000+ With proven specificity

  • Readout

    pg/mL Or NPX relative units

  • Runs on

    Signature Q100

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Actionable insights.
Clinical breakthroughs.

Olink’s scalable PEA platform empowers a seamless transition from large-scale biomarker discovery to developing and validating protein signatures with clinical utility.

Case study

Multiple sclerosis activity assessment with serum-based protein panel

Following the analysis of over 1,400 proteins in serum samples of MS patients with PEA, an Olink Focus panel was developed for further verification of the results. The work resulted in an 18-protein serum-based assay for assessment of disease activity, which has undergone both analytical and clinical validation for LDT use.

15 min read

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Case study

CSF proteome profiling across the Alzheimer’s disease spectrum

Olink technology was used to measure close to 1,000 proteins in cerebrospinal fluid samples of patients with mild cognitive impairment, Alzheimer’s disease (AD), and non-AD dementia, which led to the development of custom Olink Focus panels that could effectively distinguish AD from controls and the other dementia types.

9 min read

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Case study

Early screening of ovarian cancer

Circulating plasma levels of over 1,000 proteins were measured in patients with benign vs malignant ovarian cancer, following which a custom 11-plex Olink Focus panel was developed, validated, and shown to accurately differentiate benign tumors from ovarian cancer.

7 min read

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Your Olink Focus journey

When you have defined an informative set of proteins from running the Olink Explore series or Olink Target series, we can work with you to design and develop your own Olink Focus panel consisting of up to 21 biomarkers selected from the full Olink library.

Step 1

Design

Together with you, we will create an Olink Focus panel design based on your project-specific data.

Step 2

Development

Your Olink Focus panel is developed and analytically characterized to meet your specific study requirements. Using your samples, performance is optimized for your intended application.

Step 3

Delivery

Your Olink Focus panels are delivered directly to you or the lab that will run the analysis. A certificate of analysis and panel data file for software analysis are also provided.

Discover protein biomarker lists

Explore protein lists curated by the Olink Scientific Affairs team that highlight clinical progress achieved by applying high-throughput proteomics from biomarker discovery to clinical utility.

Studies run on Olink Focus

Peer-reviewed articles from Olink customers who have taken the real-life journey from high-multiplex biomarker discovery to developing and validating high-performance protein signatures with actionable clinical utility.

Selected Olink Focus publications

Clinical Immunology

Clinical validation of a multi-protein, serum-based assay for disease activity assessments in multiple sclerosis

Chitnis T., Foley J., Ionete C. et al.
Olink Focus

Olink Focus

Nature Communications

CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease

del Campo M., Vermunt L., Peeters C. et al.
Selected publication

Communications Medicine

Data-driven analysis of a validated risk score for ovarian cancer identifies clinically distinct patterns during follow-up and treatment

Enroth S., Ivansson E., Lindberg J. et al.
Selected publication

Documents

Below you will find a few documents related to this product. For the complete documentation including SDS, user manuals, technical notes and more, visit the documents section.

DocumentsTypeFile
Development and validation of customized PEA biomarker panels with clinical utility
White paper
High consistency between qPCR readout instruments for Olink® data technical note
Technical Notes
Download PDF
Multiple analysis of inflammatory proteins: a comparative study across multiple platforms
White paper

A flexible platform that accelerates your research

Olink’s scalable technology provides optimized solutions for every stage of the biomarker workflow, from high-throughput discovery through validation and clinical utility.

Get help choosing. Talk to a Specialist.

Olink Explore HT

Measure 5,400+ proteins with proven specificity to gain an understanding of disease at the protein level.

Proteins

5,400+ With proven specificity

Sample

2 µL Plasma, serum & more

Learn more

Olink Flex

Run individually tailored studies by combining up to 21 biomarkers from our extensive library with minimal sample volume.

Proteins

~200 Pre-validated assays

Sample

1 µL Plasma, serum & more

Learn more

Olink Target 96

Target specific disease areas or key biological processes with multiplex immunoassay panels.

Proteins

1,100+ On 15 targeted panels

Sample

1 µL Plasma, serum & more

Learn more

Olink Target 48

Extensively validated and carefully selected biomarkers for a comprehensive view of cytokine signaling and inflammatory processes.

Proteins

89 On 2 panels

Sample

1 µL Plasma, serum & more

Learn more