SCALLOP

SCALLOP Research Arm comprises numerous PIs from various research institutions that have joined the effort, contributing to a wealth of summary-level data from over 70,000 patients and controls across more than 45 cohort studies.

SCALLOP Clinical Trial Arm was introduced after the research arm, and is dedicated to establishing a pre-competitive repository for proteomics data in longitudinal samples to investigate dynamic proteomics changes in healthy volunteers and placebo/standard of care response across disease indications.

As the research arm database expands and the clinical trial arm develops, SCALLOP welcomes new members to join this collaborative endeavor.

For more information, please contact Anders Mälarstig (SCALLOP project chair).

Each SCALLOP member works on human study collections from the general population, clinical trials or patients with certain diseases such as coronary artery disease, rheumatoid arthritis, bipolar disease, heart failure, dementias or metabolic syndrome.

The aim of the SCALLOP consortium is to identify novel molecular connections and protein biomarkers that are causal in diseases.

This work starts with identification of so called protein quantitative trait loci, pQTLs, which are robust connections between a gene variant and the levels of a protein.

The SCALLOP consortium is currently underway with mapping novel pQTLs for several hundreds of proteins in extensive sample sizes, something which will yield much deeper insights into the trans-regulation of plasma proteins than has been possible to date.

Below you will find the documents related to Scallop.

Here are selected publications from SCALLOP. For a full list, browse our publication library and search for ‘SCALLOP’ to see peer-reviewed publications from consortium members as well from other scientists utilizing published SCALLOP data.