Population-scale proteogenomics
Next-generation high-throughput proteomics empowers genetically-informed assessment of protein causality and the confident identification of novel drug targets. Adding proteomics to population-scale genetic datasets takes genomics a major step closer to phenotype. This opens new possibilities to explore biological pathways and their interconnections.
A new paradigm
Advancements in collaborative approaches, access to extensive biobanks, and the scaling of proteomics technologies are driving a paradigm shift towards more precise and predictive biomedical research.
Olink Insight
Examine over 300,000 individual protein-disease associations and explore the biological variation of Olink proteins from about 50,000 individuals across three continents in the UK Biobank and other cohorts. Olink Insight is a free online bioinformatic app.
Selected publications
Read groundbreaking studies showcasing how next-generation proteomics enables genetic assessment of protein causality and novel drug targets, closing the gap from genotype to phenotype.
Selected publications
Selected webinars
Dr. Ryan Dhindsa explains how the analysis of over 50,000 human exomes from the UKB proteomics project uncovered links between rare protein-coding genetic variants and nearly 3,000 plasma proteins. Over 151,000 significant genotype-protein associations were identified, 5,400 of which corresponded to rare variants. These findings uncover previously unknown insights into disease biology that can help accelerate the identification of new therapeutic targets and biomarkers.
A flexible platform that accelerates your research
Olink’s scalable technology provides optimized solutions for every stage of the biomarker workflow, from high-throughput discovery through validation and clinical utility.
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Olink Explore HT
Measure 5,400+ proteins with proven specificity to gain an understanding of disease at the protein level.
Proteins
5,400+ With proven specificity
Sample
2 µL Plasma, serum & more
Olink Flex
Run individually tailored studies by combining up to 21 biomarkers from our extensive library with minimal sample volume.
Proteins
~200 Pre-validated assays
Sample
1 µL Plasma, serum & more
Olink Focus
Custom designed panels that transition you from biomarker discovery to clinical utility of protein signatures.
Proteins
Up to 21 Pre-validated assays
Sample
1 µL Plasma, serum & more