Scientific publications

Blood Advances, 2025
Population-scale Analysis Reveals Germline Loss of SERPING1 (C1-Inhibitor) is a Polyphenotypic Thrombotic Disorder

Rodriguez Espada A., Haj A., Jurgens S. et al.

Cureus, 2025
Mendelian Randomization Identifies IL-4, IL-6, CCL19, and DNER as Potential Causal Inflammatory Proteins in Allergic Rhinitis: Evidence Partially Supported by Transcriptomics and Protein Interaction Analysis

Quan S., Zhang F.

Nature Communications, 2025
Contribution of leukocyte telomere length to cardiovascular disease onset from genome-wide cross-trait analysis

Qiao J., Wang Q., Zhao Y. et al.

Nature Communications, 2025
Shared genetic architecture contributes to risk of major cardiovascular diseases

Qiao J., Jiang L., Cai L. et al.

JAMA Dermatology, 2025
Mediterranean Diet and Patients With Psoriasis

Perez-Bootello J., Berna-Rico E., Abbad-Jaime de Aragon C. et al.

RMD Open, 2025
Decreased GPR55 expression links B-cell activation and vascular remodelling in atherosclerosis in patients with early rheumatoid arthritis

Miranda-Prieto D., Alperi-López M., Pérez-Álvarez ?. et al.

Circulation: Heart Failure, 2025
Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure

Melenovsky V., Jarolim P., Kutilkova E. et al.

Inflammatory Bowel Diseases, 2025
Genome-Wide Aggregated Trans-Effects Analysis Implicates Deficient Type III Interferon Signaling as a Key Cause of Inflammatory Bowel Disease

McKeigue P., Iakovliev A., Erabadda B. et al.

Signal Transduction and Targeted Therapy, 2025
Liquid biomarkers associate with TGF-β Type I receptor and hypoxia in kidney cancer

Mallikarjuna P., Erdem C., Beorlegui R. et al.

PLOS Computational Biology, 2025
Exploration of potential novel drug targets for rheumatoid arthritis by plasma proteome screening

Ma Z., Chen R., Feng Z.

Journal of Dermatological Science, 2025
Molecular profile of interleukin-17RA blockade by brodalumab in Japanese patients with psoriasis: Results from the ESPRIT study

Krueger J., Morita A., Uchida-Yamada M. et al.

Communications Chemistry, 2025
Current landscape of plasma proteomics from technical innovations to biological insights and biomarker discovery

Kirsher D., Chand S., Phong A. et al.

Advanced Science, 2025
Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases

Jin Z., Chen Q., Zhou L. et al.

Psychoneuroendocrinology, 2025
Association of psychosocial stress and poverty with plasma and extracellular vesicle mitochondrial DNA levels

Hunter T., Noren Hooten N., Maul H. et al.

BMJ Open, 2025
Mendelian randomisation and single-cell transcriptomic analyses reveal serotonin promotes multiple sclerosis progression by suppressing adenosine deaminase activity

Huang L., Shi J., Li H. et al.

Journal of Ophthalmology, 2025
Genetically Prioritized Plasma Proteins as Candidate Therapeutic Targets for Dry Age‐Related Macular Degeneration

Hou J., Guo J., Shen W. et al.

Science Translational Medicine, 2025
Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation

He Z., Glass M., Venkatesan P. et al.

Journal of Stroke, 2025
LIGHT/TNFSF14 Levels in Carotid Plaques Are Associated With Symptomatic Cerebrovascular Disease

Gonçalves I., Sun J., Singh P. et al.

European Journal of Pain, 2025
Multifactorial Machine Learning Algorithm Integration of Pain Mechanisms Can Predict the Efficacy of 3‐Week NSAID Plus Paracetamol in Patients With Painful Knee Osteoarthritis

Giordano R., Arendt‐Nielsen L., Hertel E. et al.

Open Heart, 2025
Association between circulating biomarkers and atrial fibrillation burden in patients with paroxysmal atrial fibrillation: a subanalysis of the RACE V study

Frausing M., Rienstra M., Kronborg M. et al.