Nature Communications, 2023
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Brown A., Fernandez-Tajes J., Hong M. et al.

Journal of Cancer Research and Clinical Oncology, 2023
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study

Pham T., Nimptsch K., Papadimitriou N. et al.

Aging Cell, 2023
Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort

Chen J., Doyle M., Fang Y. et al.

Journal of Cerebral Blood Flow & Metabolism, 2023
A cluster of blood-based protein biomarkers associated with decreased cerebral blood flow relates to future cardiovascular events in patients with cardiovascular disease

Overmars L., Kuipers S., van Es B. et al.

iScience, 2023
Transcriptomic and proteomic assessment of tocilizumab response in a randomized controlled trial of patients hospitalized with COVID-19

Shivram H., Hackney J., Rosenberger C. et al.

Nature Immunology, 2023
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Zhao J., Stacey D., Eriksson N. et al.

eClinicalMedicine, 2023
Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory mantle cell lymphoma (CITADEL-205): a phase 2 study

Zinzani P., Trněný M., Ribrag V. et al.

Research and Practice in Thrombosis and Haemostasis, 2023
Tranexamic acid in a mouse model of cerebral amyloid angiopathy: setting the stage for a novel stroke treatment approach

Liu Z., McCutcheon F., Ho H. et al.

Environmental Science & Technology, 2023
Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study

Ni W., Breitner S., Nikolaou N. et al.

Brain, Behavior, and Immunity, 2023
Machine learning models of plasma proteomic data predict mood in chronic stroke and tie it to aberrant peripheral immune responses

Bidoki N., Zera K., Nassar H. et al.

Nature Aging, 2023
Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging

Rosoff D., Mavromatis L., Bell A. et al.

International Journal of Obesity, 2023
Comprehensive analyses of circulating cardiometabolic proteins and objective measures of fat mass

Titova O., Brunius C., Warensjö Lemming E. et al.

European Journal of Internal Medicine, 2023
Clinical features and immune mechanisms directly linked to the altered liver function in patients with rheumatoid arthritis

Arias-de la Rosa I., Ruiz-Ponce M., Cuesta-López L. et al.

BMC Medicine, 2023
Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Zhou L., Zhu L., Wu X. et al.

Clinical Cancer Research, 2023
Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Sarén T., Ramachandran M., Gammelgård G. et al.

Frontiers in Cardiovascular Medicine, 2023
Baseline fibroblast growth factor 23 is associated with long-term mortality in ST-elevation myocardial infarction—results from the augsburg myocardial infarction registry

Schmitz T., Wein B., Heier M. et al.

Clinical Cancer Research, 2023
A Phase II Trial of the CD40 Agonistic Antibody Sotigalimab (APX005M) in Combination with Nivolumab in Subjects with Metastatic Melanoma with Confirmed Disease Progression on Anti-PD-1 Therapy

Weiss S., Sznol M., Shaheen M. et al.

Clinical Journal of the American Society of Nephrology, 2023
Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait

Cai Y., Franceschini N., Surapaneni A. et al.

Cytokine, 2023
The role of NLRP3 in regulating gingival epithelial cell responses evoked by Aggregatibacter actinomycetemcomitans

Jayaprakash Demirel K., Wu R., Neves Guimaraes A. et al.

Allergy, 2023
Mechanisms of gut epithelial barrier impairment caused by food emulsifiers polysorbate 20 and polysorbate 80

Ogulur I., Yazici D., Pat Y. et al.