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The Integration of Olink Proteomics with Transcriptomics Elucidates that TNF-α Induces Senescence and Apoptosis in Transplanted Mesenchymal Stem Cells

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Nature Genetics, 2025
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

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Nature Communications, 2025
Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure

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ESMO Open, 2025
Tislelizumab plus nab-paclitaxel and cisplatin as induction immunochemotherapy for organ preservation of locally advanced hypopharyngeal squamous cell carcinoma: a single-arm phase II trial

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Clinical Cancer Research, 2025
First-in-Human Phase 1/2 Study of INCAGN01876, a Glucocorticoid-Induced Tumor Necrosis Factor Receptor Agonist, in Patients with Advanced or Metastatic Solid Tumors

Hamid O., Cardin D., Hodi F. et al.

International Journal of Molecular Sciences, 2025
In-Depth Characterization of L1CAM+ Extracellular Vesicles as Potential Biomarkers for Anti-CD20 Therapy Response in Relapsing–Remitting Multiple Sclerosis

Anandan S., Maciak K., Breinbauer R. et al.

Alzheimer's & Dementia, 2025
Distinct inflammatory profiles in young‐onset versus late‐onset Alzheimer's disease

Thapa S., Anastassiadis C., Vasilevskaya A. et al.

Scientific Reports, 2025
Association between inflammatory proteins and rotator cuff tears: a bidirectional Mendelian randomization study

Wang Y., Xu B., Ma C. et al.

Nutrients, 2025
Soluble Oncoimmunome Signatures Predict Muscle Mass Response to Enriched Immunonutrition in Cancer Patients: Subanalysis of a Multicenter Randomized Clinical Trial

Cuesta-Sancho S., Gomez J., García-Luna P. et al.

Immunity, 2025
Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine

Yu Q., Jiang D., Zhao T. et al.

Environmental Science & Technology, 2025
The Associations of Air Pollution Mixture Exposure with Plasma Proteins in an Elderly U.S. Panel

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Communications Biology, 2025
Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections

Kajihara K., Yan D., Seim G. et al.

International Urology and Nephrology, 2025
Unraveling the causal link between inflammatory cytokines and hypertensive renal disease: a Mendelian randomization analysis

Gong X., Xu X., He M. et al.

Nature Medicine, 2025
Large language model-based biological age prediction in large-scale populations

Li Y., Huang Q., Jiang J. et al.

Nature Communications, 2025
Genome-wide association study of pulpal and apical diseases

Salminen A., Hyvärinen K., Ritari J. et al.

Translational Psychiatry, 2025
Exosomes from high-altitude cerebral edema patients induce cognitive dysfunction by altering oxidative stress responses in mice

Fu Q., Qiu R., Tang Q. et al.

Alzheimer's Research & Therapy, 2025
CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer’s disease patients

Oosthoek M., Vijverberg E., Blujdea E. et al.

Cell, 2025
Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia

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Signal Transduction and Targeted Therapy, 2025
Exploratory phase II trial of an anti-PD-1 antibody camrelizumab combined with a VEGFR-2 inhibitor apatinib and chemotherapy as a neoadjuvant therapy for triple-negative breast cancer (NeoPanDa03): efficacy, safety and biomarker analysis

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International Journal of Molecular Sciences, 2025
Hydroxytyrosol Reprograms the Tumor Microenvironment in 3D Melanoma Models by Suppressing ERBB Family and Kinase Pathways

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