Mucosal Immunology, 2024
Gut-homing and intestinal TIGITnegCD38+ memory T cells acquire an IL-12-induced, ex-Th17 pathogenic phenotype in a subgroup of Crohn’s disease patients with a severe disease course

Heredia M., Barendregt D., Tindemans I. et al.

Nature Genetics, 2024
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience

Jurgens S., Rämö J., Kramarenko D. et al.

Neurobiology of Disease, 2024
ANGPTL4-mediated microglial lipid droplet accumulation: Bridging Alzheimer's disease and obesity

Li N., Wang X., Lin R. et al.

Medicine, 2024
The application of sphingomyelin in mediating the causal role of the T-cell surface glycoprotein CD5 in Crohn’s disease: A two-step Mendelian randomization study

Li X., Yao X., Wen J. et al.

Cell Reports Medicine, 2024
Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response

Brandes-Leibovitz R., Riza A., Yankovitz G. et al.

Brain Communications, 2024
Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders

Fernandes Gomes B., Kumar A., Ashton N. et al.

Journal of Translational Medicine, 2024
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements

Manasherob R., Warren S., Arora P. et al.

Endocrine and Metabolic Science, 2024
Acute and prolonged ketosis lower serum IGF-I levels in human subjects

Svart M., Kjaergaard A., Luong T. et al.

The Journal of Clinical Hypertension, 2024
Rheumatoid Arthritis, Circulating Inflammatory Proteins, and Hypertension: A Mendelian Randomization Study

Jia G., Guo T., Liu L. et al.

Journal of Autoimmunity, 2024
Trained innate immunity in response to nuclear antigens in systemic lupus erythematosus

Yanginlar C., Rother N., Post T. et al.

Nature Communications, 2024
A self-amplifying RNA RSV prefusion-F vaccine elicits potent immunity in pre-exposed and naïve non-human primates

Vijayan A., Vogels R., Groppo R. et al.

Metabolic Brain Disease, 2024
Individuals with SATB2-associated syndrome have impaired vitamin and energy metabolism pathways

Collu R., Zarate Y., Xia W. et al.

Transfusion and Apheresis Science, 2024
Mechanistic insights from a pilot exploratory study of the dynamic proteomic changes during plasma exchange in patients with acute liver failure

Jauniaux B., Burke L., Snook N. et al.

Frontiers in Immunology, 2024
A targeted proteomics screen reveals serum and synovial fluid proteomic signature in patients with gout

Huang Z., Zhong X., Zhang Y. et al.

Neurology Neuroimmunology & Neuroinflammation, 2024
Proteomics Reveals Age as Major Modifier of Inflammatory CSF Signatures in Multiple Sclerosis

Held F., Makarov C., Gasperi C. et al.

Science Translational Medicine, 2024
Sex differences and immune correlates of Long Covid development, symptom persistence, and resolution

Hamlin R., Pienkos S., Chan L. et al.

GeroScience, 2024
Plasma proteomic signature of risk and prognosis of frailty in the UK Biobank

Xu J., Liu J., Tang J. et al.

Journal of Leukocyte Biology, 2024
Interleukin-10 inhibits important components of trained immunity in human monocytes

Röring R., Scognamiglio F., de Jong L. et al.

Journal of Stroke and Cerebrovascular Diseases, 2024
Sodium-glucose cotransporter protein 2 inhibition, plasma proteins, and ischemic stroke: A mediation Mendelian randomization and colocalization study

Chen Z., Meng H., Guo Y. et al.

GeroScience, 2024
Plasma proteomics-based brain aging signature and incident dementia risk

Kou M., Ma H., Wang X. et al.