Genes & Immunity, 2025
A multi-omics approach reveals dysregulated TNF-related signaling pathways in circulating NK and T cell subsets of young children with autism

Nour-Eldine W., Ltaief S., Ouararhni K. et al.

Psychiatry Investigation, 2025
Cytokine-Related Genes and Inflammatory Profiles as Potential Biomarkers in Major Depressive Disorder

Oh H., Kong N., Jung S. et al.

Aging Cell, 2025
Proteomic Signatures of Epigenetic Age in African Green Monkey Cerebrospinal Fluid and Plasma

Elsworth J., Neutzner A., Roux J. et al.

Cell Reports Medicine, 2025
A human milk oligosaccharide alters the microbiome, circulating hormones, and metabolites in a randomized controlled trial of older adults

Carter M., Demis D., Perelman D. et al.

Clinical Research in Cardiology, 2025
Targeted proteomic profiling of transcatheter edge-to-edge repair failure in patients with mitral regurgitation and heart failure

Di Pasquale M., Ravassa S., Pagnesi M. et al.

Intensive Care Medicine, 2025
Identification of transcriptomic sepsis endotypes in sub-Saharan Africa: derivation, validation, and global alignment in two Ugandan cohorts

Cummings M., Lutwama J., Tomoiaga A. et al.

Journal of Cancer, 2025
Comprehensive Mendelian randomization and colocalization analysis of plasma proteomics to identify new therapeutic targets for bladder cancer

Zuo J., Chen J., Tan Z. et al.

Stem Cell Reviews and Reports, 2025
The Integration of Olink Proteomics with Transcriptomics Elucidates that TNF-α Induces Senescence and Apoptosis in Transplanted Mesenchymal Stem Cells

Zhou Y., Xiao J., Peng S. et al.

Nature Communications, 2025
Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure

Lindman B., Perry A., Lance M. et al.

ESMO Open, 2025
Tislelizumab plus nab-paclitaxel and cisplatin as induction immunochemotherapy for organ preservation of locally advanced hypopharyngeal squamous cell carcinoma: a single-arm phase II trial

Gui L., Xie Z., Zhang W. et al.

Cancer Research, 2025
Dasatinib Remodels the Tumor Microenvironment and Sensitizes Small Cell Lung Cancer to Immunotherapy

Redin E., Otegui N., Santos M. et al.

Clinical Cancer Research, 2025
First-in-Human Phase 1/2 Study of INCAGN01876, a Glucocorticoid-Induced Tumor Necrosis Factor Receptor Agonist, in Patients with Advanced or Metastatic Solid Tumors

Hamid O., Cardin D., Hodi F. et al.

International Journal of Molecular Sciences, 2025
In-Depth Characterization of L1CAM+ Extracellular Vesicles as Potential Biomarkers for Anti-CD20 Therapy Response in Relapsing–Remitting Multiple Sclerosis

Anandan S., Maciak K., Breinbauer R. et al.

Alzheimer's & Dementia, 2025
Distinct inflammatory profiles in young‐onset versus late‐onset Alzheimer's disease

Thapa S., Anastassiadis C., Vasilevskaya A. et al.

Nutrients, 2025
Soluble Oncoimmunome Signatures Predict Muscle Mass Response to Enriched Immunonutrition in Cancer Patients: Subanalysis of a Multicenter Randomized Clinical Trial

Cuesta-Sancho S., Gomez J., García-Luna P. et al.

Immunity, 2025
Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine

Yu Q., Jiang D., Zhao T. et al.

Environmental Science & Technology, 2025
The Associations of Air Pollution Mixture Exposure with Plasma Proteins in an Elderly U.S. Panel

Tang Z., Wang Y., Sarnat J. et al.

Communications Biology, 2025
Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections

Kajihara K., Yan D., Seim G. et al.

International Urology and Nephrology, 2025
Unraveling the causal link between inflammatory cytokines and hypertensive renal disease: a Mendelian randomization analysis

Gong X., Xu X., He M. et al.

Nature Medicine, 2025
Large language model-based biological age prediction in large-scale populations

Li Y., Huang Q., Jiang J. et al.