Single-Cell and Plasma Proteomics Do Not Differentiate Patients With and Without SARS-CoV-2 Antigenemia in Convalescence in a Cohort of 100 Patients
Open Forum Infectious Diseases, 2025
Pienkos S., Swank Z., Hamlin R., Rao M., Grant P., Bonilla H., Jacobson K., Jagannathan P., Singh U., Walt D., Subramanian A., Blish C.
| Disease area | Application area | Sample type | Products |
|---|---|---|---|
Infectious Diseases | Patient Stratification | Plasma |  Olink Target 96 |
Abstract
Plasma samples obtained approximately 3 (n = 100) and 12 months (n = 78) after acute SARS-CoV-2 infection were tested for S1, spike, and N antigens. There were no significant differences in plasma proteins or single-cell protein expression levels on immune cells between those with and without plasma antigen detected.