Olink

Olink®
Part of Thermo Fisher Scientific

Data Ecosystem
This stage of the Olink data journey

Explore, analyze, and interpret your proteomic data to identify meaningful signals, prioritize proteins of interest, and understand their biological context. Use Olink tools, population-scale datasets, flexible analysis workflows, and trusted support to move from complex data to findings that inform your next research question.

Workflow

Where data interpretation fits in your data journey

Once analysis has identified findings of interest, the next step is understanding what they mean biologically. Connect protein signals to disease, pathways, population-scale evidence, and other biological context to prioritize findings and define the next research question.

Study Design

Plan your proteomics study with the right design, sample strategy, and endpoints for confident downstream analysis.

Explore

Data Generation & QC

Generate high-quality NPX data and apply robust QC so results are reliable before integration & comparison.

Explore

Data Integration & Normalization

Move beyond isolated datasets — normalize & bridge NPX data, connect to population-scale cohorts, & compare across studies.

Explore

Discovery & Biological Interpretation

Interpret findings with annotation tools, statistical methods, & expert guidance from Olink Data Science Services.

    Tools & services
    Find the signals that matter

    Explore patterns, compare groups, and identify proteins associated with your research question. Use guided statistical analysis in Olink Insight, flexible R-based workflows with Olink Analyze, or your own analytical pipeline to prioritize findings and determine what to investigate further.

    Biological interpretation
    Add biological context to your findings

    Once analysis identifies proteins of interest, Olink Insight helps you understand what those findings mean biologically. Adding complementary biological evidence can help you distinguish the signals worth pursuing, develop stronger hypotheses, and define your next research question.

    Biological context

    How Olink Insight helps

    Detection frequencies

    See how proteins are detected across four different sample matrices in approximately 40 real-world Olink Explore HT projects.

    Disease associations

    See how proteins are associated with disease risk in population-scale datasets and examine the evidence around your findings.

    Pathways and processes

    Place proteins within known pathways and biological processes to identify shared mechanisms and broader biological themes.

    Tissue specificity

    Explore where proteins are expressed to add tissue context and help interpret the biology behind observed signals.

    Population evidence

    Use large-scale cohort data, including UK Biobank, to put findings into a broader population context.

    Genetic evidence

    Add proteogenomic information such as pQTLs and heritability to investigate genetic support for proteins of interest.

    Therapeutic relevance

    Identify proteins linked to approved or investigational therapeutics to understand existing drug-target context.

    Flexible analysis
    Work in your own analysis environment

    Integrate Olink data into your existing R or Python workflows, data platforms, multiomics analyses, visualization tools and custom models. Use Olink tools where they add value while keeping control of your analytical workflow.

    Reference datasets
    Take advantage of landmark datasets to empower your study

    Olink Insight offers interactive data stories based on landmark datasets such as the UK Biobank, China Kadoorie Biobank, Arivale wellness cohort, and the Uppsala–Umea cancer cohort to:

    • Explore associations between ~3,000 proteins and over 100 diseases
    • View normal range variations, disease overviews and Kaplan–Meier plots
    • Annotate your own protein lists with disease associations, pathway information, genetic variants, and drug target status.
    Advanced analysis
    Go deeper when your question requires it

    Olink Insight is the primary self-guided route for biological interpretation. For questions requiring code-based analysis, tailored support, training, or specialist capabilities, extend your workflow with Olink Analyze, Olink Data Science Services, or compatible third-party tools.

    Learning resources
    See Olink Insight in action

    Watch the Post-Run Analysis walkthrough to see how Olink Insight supports automatic annotation and biological interpretation once statistical analysis has identified proteins of interest.