Olink

Olink®
Part of Thermo Fisher Scientific

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Gene
MKRN4P

Uniprot
Q13434

Protein
Putative E3 ubiquitin-protein ligase makorin-4

See alternative names Makorin RING finger protein pseudogene 4,
Makorin RING finger protein pseudogene 5,
RING finger protein 64,
RING-type E3 ubiquitin transferase makorin-4,
Zinc finger protein 127-Xp,
Zinc finger protein 127-like 1

Uniprot Function Description

May act as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Sample type

Recommended sample types are human plasma and serum. For other sample types e.g cerebrospinal fluid, (CSF), tissue or cell lysate, please contact support@olink.com for more information. Please note that protein expression levels are expected to vary in different sample types and certain assays may be affected by interfering substances such as hemolysate.

Precision

Precision (repeatability) is calculated from linearized NPX values over LOD.

Within run precision Coefficient of Variation (CV)
N/A

Analytical measuring range

The technical data reported below refers to the measured value in the in vitro validation assays run using known concentrations of recombinant antigen.

LOD (NPX)
1.6
Hooked
No
Hook (NPX)
12.5

Dilution factor

For optimal assay readout, Olink assays are run using different dilutions of the original samples e.g. undiluted, 1:10, or higher. The dilution factor for this assay is noted below and should be taken into account when estimating the appropriate addressable biological concentration of the protein based on the in vitro validation data.

Dilution factor
1:1

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents – go to Document download center

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