Olink

Olink®
Part of Thermo Fisher Scientific

Explore HT

Gene
PPP2R5A

Uniprot
Q15172

Protein
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

See alternative names PP2A B subunit isoform B'-alpha,
PP2A B subunit isoform R5-alpha,
PP2A B subunit isoform PR61-alpha,
PP2A B subunit isoform B56-alpha

Uniprot Function Description

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Sample type

Recommended sample types are human plasma and serum. For other sample types e.g cerebrospinal fluid, (CSF), tissue or cell lysate, please contact support@olink.com for more information. Please note that protein expression levels are expected to vary in different sample types and certain assays may be affected by interfering substances such as hemolysate.

Precision

Precision (repeatability) is calculated from linearized NPX values over LOD.

Within run precision Coefficient of Variation (CV)
31%

Analytical measuring range

The technical data reported below refers to the measured value in the in vitro validation assays run using known concentrations of recombinant antigen.

LOD (NPX)
2
Hooked
No
Hook (NPX)
8.7

Dilution factor

For optimal assay readout, Olink assays are run using different dilutions of the original samples e.g. undiluted, 1:10, or higher. The dilution factor for this assay is noted below and should be taken into account when estimating the appropriate addressable biological concentration of the protein based on the in vitro validation data.

Dilution factor
1:1

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents – go to Document download center

Search all Biomarkers