Reveal
Gene
ITGB1BP2
Uniprot
Q9UKP3
Protein
Integrin beta-1-binding protein 2
See alternative names Melusin
Uniprot Function Description
May play a role during maturation and/or organization of muscles cells.
Sample type
Recommended sample types are human plasma and serum. For other sample types e.g cerebrospinal fluid, (CSF), tissue or cell lysate, please contact support@olink.com for more information. Please note that protein expression levels are expected to vary in different sample types and certain assays may be affected by interfering substances such as hemolysate.
Precision
Precision (repeatability) is calculated from linearized NPX values over LOD.
Dilution factor
For optimal assay readout, Olink assays are run using different dilutions of the original samples e.g. undiluted, 1:10, or higher. The dilution factor for this assay is noted below and should be taken into account when estimating the appropriate addressable biological concentration of the protein based on the in vitro validation data.
Sample distribution plot
The plot below shows the levels of protein measured in a number of commercial plasma samples. The distributions of samples are presented as boxplots, with the first quartile, median and third quartile marked. Whiskers are set to 10ᵗʰ and 90ᵗʰ percentiles. Replicates <10ᵗʰ and >90ᵗʰ percentile are presented as outlier replicates. Healthy control samples are shown in blue and samples obtained from patients with a range of diseases are shown in red. The latter include inflammatory, cardiovascular, autoimmune & neurological diseases, as well as cancer. The data is shown to give a general idea of the sort of data range to expect, but cannot cover all potential levels that may be seen in clinical samples.
Biomarker Validation Data
Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents – go to Document download center