Olink

Olink®
Part of Thermo Fisher Scientific

Target 96 Cardiometabolic

Gene
FCN2

Uniprot
Q15485

Protein
Ficolin-2

See alternative names Serum lectin p35,
L-ficolin,
Hucolin,
37 kDa elastin-binding protein,
Collagen/fibrinogen domain-containing protein 2,
EBP-37,
Ficolin-B,
Ficolin-beta

Uniprot Function Description

May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.

Sample type

Recommended sample types are EDTA plasma and serum. A range of additional sample types are compatible with the technology (PEA), including citrate plasma, heparin plasma, cerebrospinal fluid, (CSF), tissue and cell lysates, fine needle biopsies, microdialysis fluid, cell culture media, dried blood spots, synovial fluid, saliva, plaque extract and microvesicles. Please note that protein expression levels are expected to vary in different sample types. Certain assays are differentially affected by interfering substances such as hemolysate. Download any of our Data Validation documents or contact support@olink.com for more information.

Precision

Precision (repeatability) is calculated from linearized NPX values over LOD.

Within run precision Coefficient of Variation (CV)
14%
Between run precision Coefficient of Variation (CV)
8%

Analytical measuring range

The technical data reported below refers to the measured value in the in vitro validation assays run using known concentrations of recombinant antigen. Please note that these figures are for reference only and CANNOT be used to convert NPX values to absolute concentrations for proteins measured in plasma or serum samples.

LOD (pg/mL)
7.6
LLOQ (pg/mL)
15.0
ULOQ (pg/mL)
62500
Hook (pg/mL)
125000
Range (logs)
3.6

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents – go to Document download center

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