Scientific publications

Brain Communications, 2025

An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis

van Eijk R., Steyn F., Janse van Mantgem M. et al.

Arthritis Research & Therapy, 2025

Integrated analysis of dermatomyositis reveals heterogeneous immune infiltration and interstitial lung disease-associated endotype

Xu X., Qiu T., Sun K. et al.

International Journal of Chronic Obstructive Pulmonary Disease, 2025

The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD

Yan K., Wang Y., Xin P.

Movement Disorders, 2025

Effects of Montelukast on Neuroinflammation in Parkinson's Disease: An Open Label Safety and Tolerability Trial with CSF Markers and [¹¹C]PBR28 PET

Wallin J., Forsberg A., Svenningsson P.

ImmunoTargets and Therapy, 2025

Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy

Ke C., Yu Y., Li J. et al.

Journal for ImmunoTherapy of Cancer, 2025

Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights

Wang X., Tian H., Chi Z. et al.

eBioMedicine, 2025

Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigation

Michaëlsson K., Zheng R., Baron J. et al.

Nature Cardiovascular Research, 2025

Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction

Rasooly D., Giambartolomei C., Peloso G. et al.

Translational Vision Science & Technology, 2025

Genetics of Circulating Inflammatory Proteins and Iridocyclitis: An Exploratory Mendelian Randomization Study

Liu H., Li F., Wang F. et al.

Nature, 2025

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

Braun D., Moranzoni G., Chea V. et al.

Cell Death Discovery, 2025

Pan-caspase inhibitors induce secretion of HIV-1 latency reversal agent lymphotoxin-alpha from cytokine-primed NK cells

Hajikhezri Z., Zygouras I., Sönnerborg A. et al.

Scientific Reports, 2025

Untargeted metabolomic and proteomic analysis implicates SIRT2 as a novel therapeutic target for diabetic nephropathy

Zhang R., Chang R., Wang H. et al.

Journal of Proteome Research, 2025

Serum Immune-Response Protein Biomarkers Based on Olink Technology for Diagnosis of Ischemic Stroke

Wang H., Zhao T., Zeng J. et al.

Journal of Ethnopharmacology, 2025

Lianhua Qingke Tablet in severe pneumonia: Clinical efficacy and immunoregulatory mechanisms

Jin P., Qi H., Zhao J. et al.

Journal of Translational Medicine, 2025

Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1

Wan L., Lam S., Huang H. et al.

Clinical Cancer Research, 2025

Corticosteroid-Dependent Association between Prognostic Peripheral Blood Cell-Free DNA Levels and Neutrophil-Mediated NETosis in Patients with Glioblastoma

Till J., Seewald N., Yazdani Z. et al.

Molecular Neurobiology, 2025

Prospective Investigation Unravels Plasma Proteomic Links to Dementia

Li J., Li J., Chen S. et al.

Rheumatology, 2025

Plasma proteomics for risk prediction and identification of novel drug targets in systemic lupus erythematosus

Yang S., Zhang Y., Ye Z. et al.

Nature Medicine, 2025

Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection

Duff E., Zetterberg H., Heslegrave A. et al.

Frontiers in Oncology, 2025

Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy

Uffenorde J., Hariri M., Papalanis E. et al.