The Oncologist, 2025
First-in-human phase I open-label study of the anti–TIM-3 monoclonal antibody INCAGN02390 in patients with select advanced or metastatic solid tumors

Gutierrez M., Tang S., Powderly J. et al.

The Oncologist, 2025
First-in-human phase I open-label study of the LAG-3 antagonist antibody INCAGN02385 in patients with select advanced or metastatic solid tumors

Powderly J., Gutierrez M., Balmanoukian A. et al.

Nature, 2025
Interferon-γ orchestrates leptomeningeal anti-tumour response

Remsik J., Tong X., Kunes R. et al.

Journal of Proteome Research, 2025
Dynamic Changes in Lymphocyte Subsets and Inflammation-Immune-Related Proteins in Patients with Thyroid Papillary Carcinoma before and after Radioactive Iodine Therapy

Zhang J., Shi L., Zhang Z. et al.

Scientific Reports, 2025
Dissecting immune-mediated pathways in rheumatoid arthritis: A multivariate mediation analysis of antibodies and circulating proteins

Niu J., Zhang P., Liu W. et al.

BMC Neurology, 2025
CD28+ CD45RA− CD8br AC mediated the effects of Interleukin- 6 on Alzheimer's disease: A Mendelian Randomization Study

Xu R., Gao Y.

Journal for ImmunoTherapy of Cancer, 2025
Combination of a therapeutic cancer vaccine targeting the endogenous retroviral envelope protein ERVMER34-1 with immune-oncology agents facilitates expansion of neoepitope-specific T cells and promotes tumor control

Maldonado M., Gracia-Hernandez M., Le L. et al.

Blood Journal, 2025
Large B-cell lymphoma imprints a dysfunctional immune phenotype that persists years after treatment

Pelzl R., Benintende G., Gsottberger F. et al.

Blood Journal, 2025
A Multi-Omics Approach Reveals Novel Regulators of Plasma Factor V Levels: highlight on CLEC4M as a Clearance Receptor

Munsch G., Mohapatra A., van Hylckama Vlieg A. et al.

Europace, 2025
From moderate to strenuous training: unraveling mechanistic contributors and biomarkers for atrial fibrillation in exercise

Alcarraz A., Meza-Ramos A., Rubies C. et al.

Postgraduate Medical Journal, 2025
Uncovering novel metabolic and inflammatory pathways in gout using Mendelian randomization

Li Q., Guo R., Wu Z. et al.

Nature Communications, 2025
Sex differences in the genetic regulation of the human plasma proteome

Koprulu M., Wheeler E., Kerrison N. et al.

Arthritis & Rheumatology, 2025
Dietary polyunsaturated fatty acid and the risk of rheumatoid arthritis: Insights from genetic predisposition and proteomics

Chen L., Tan T., Chen Y. et al.

Medicine, 2025
Evaluation of causal links of gut microbiota and inflammatory cytokines with 10 fracture locations: A Mendelian randomization study

Ding H., Zhao X., Liu G. et al.

International Journal of Molecular Sciences, 2025
Circulating Cytokines Mediate the Protective Effect of Physical Activity on Cardiovascular Diseases: A Mendelian Randomization Mediation Analysis

Sun Y., Liu Y.

Journal of Inflammation Research, 2025
Seasonal Proteomic Variations and Biomarkers in Seasonal Allergic Rhinitis: Insights from Olink Inflammation Profiling

Shen J., Zheng X., Yan M. et al.

Journal for ImmunoTherapy of Cancer, 2025
Spatial transcriptomics highlights B cells as key contributors to a complete and durable response to chemo-immunotherapy in a patient with resectable NSCLC

Porciello N., Gallina F., Frisullo G. et al.

Journal of Reproductive Immunology, 2025
Potential therapeutic targets for ovarian hyperstimulation syndrome revealed by proteome-wide mendelian randomization and colocalization analysis

Yao B., Chen S., Chen X. et al.

Clinical Autonomic Research, 2025
Autonomic neuropathy is associated with an increase in type-1 cytokines in people living with HIV

Mueller B., Mehta M., Campbell M. et al.

Oral Oncology Reports, 2025
AI-driven biomarker discovery for early diagnosis and prognosis in oral oncology

Munnangi S., R S.