Nature, 2025
Multi-omic profiling reveals age-related immune dynamics in healthy adults

Gong Q., Sharma M., Glass M. et al.

Journal of Orthopaedic Surgery and Research, 2025
The mediation of circulating inflammatory proteins in the causal pathway from immune cells to osteoarthritis

Yuan Y., Liang X., Kang S. et al.

Communications Medicine, 2025
Translational framework linking perfluoroheptanoic acid (PFHpA) exposure to metabolic dysfunction associated steatotic liver disease in adolescents

Baumert B., Maretti-Mira A., Walker D. et al.

Neurobiology of Aging, 2025
Identifying a proteomics signature of cognitive impairment and dementia in blood and cerebrospinal fluid through a mediation analysis framework

Torrealba-Acosta G., Yang S., Calvo-Marín J. et al.

Nature Communications, 2025
Multi-cohort high-dimensional proteomics reveals early risk markers for lymphoid cancer subtypes

Kolijn P., Smith-Byrne K., Burk V. et al.

Biomarker Research, 2025
Plasma proteomics uncovers divergent molecular signatures in ischemic stroke and intracerebral hemorrhage

Núñez-Jurado D., Fernández-Vega A., del Río C. et al.

Discover Oncology, 2025
CCL20 mediates the effect of cathepsin S on hepatocellular carcinoma development insights from Mendelian randomization and bioinformatics analysis

Yuan C., Li Q., luo M. et al.

Journal for ImmunoTherapy of Cancer, 2025
Combination of a novel TCR Vβ chain-directed selective T cell activator with standard of care therapy for head and neck cancer improves antitumor responses and promotes regression of checkpoint-refractory tumor models

Rosato F., Santiago-Sanchez G., Fabian K. et al.

Frontiers in Immunology, 2025
Diagnostic efficiency of inflammatory signatures to distinguish isolated candidemia from candidemia with bacterial co-infection

Mnichowska-Polanowska M., Grygorcewicz B., Dołęgowska B. et al.

Diabetes, Obesity and Metabolism, 2025
Plasma proteomics identifies potential drug targets for diabetic polyneuropathy: Evidence from prospective cohorts and genetic analysis

Lan H., Xu S., Li H. et al.

Signal Transduction and Targeted Therapy, 2025
Piezo1 activation suppresses bone marrow adipogenesis to prevent osteoporosis by inhibiting a mechanoinflammatory autocrine loop

Wang B., Liu J., Wang Q. et al.

Journal of Thrombosis and Haemostasis, 2025
Genome-wide identification of loci associated with plasma coagulation factor IX activity

Han J., Cate V., Li-Gao R. et al.

Allergy, 2025
Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

Pat Y., Yazici D., Zeyneloglu C. et al.

Science Advances, 2025
Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiovascular diseases, and longevity

Villaplana-Velasco A., Perrot N., Hang Y. et al.

European Journal of Preventive Cardiology, 2025
Accelerated ageing predicts earlier onset of ischaemic stroke: a proteomic and transcriptomic investigation

Quek A., Teng O., Tan T. et al.

Pediatric Allergy and Immunology, 2025
Systemic inflammatory biomarkers in relation to lung function and exercise‐induced bronchoconstriction in adolescents

Ersson K., Alving K., Emtner M. et al.

Gut Microbes Reports, 2025
Gut microbiome-induced metabolites promote the role of Silybin as adjunctive drug in HIV-positive immunological nonresponders

Liu W., An M., Wang Q. et al.

RMD Open, 2025
Targeted proteomics identifies differentially expressed proteins in Sjögren’s disease with incident lymphoma

Imgenberg-Kreuz J., Fugmann C., Molin A. et al.

Journal of International Medical Research, 2025
Association between a history of hypothyroidism and incident chronic kidney disease and potential mediators: A cohort study with Mendelian randomization analysis

Zhang Y., Shen Y., Shen A. et al.

Journal of Affective Disorders, 2025
Multiplicative and additive interaction effects of vascular risk factor burden with APOE genotypes on dementia: Associations and peripheral biological mechanisms based on a large cohort study

Yang Z., Huang L., Luo X. et al.