Nature Medicine, 2025
Plasma proteomics links brain and immune system aging with healthspan and longevity

Oh H., Le Guen Y., Rappoport N. et al.

Genome Biology, 2025
Long-term DNA methylation changes mediate heterologous cytokine responses after BCG vaccination

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Diabetologia, 2025
Biomarkers of inflammation and improvement in depressive symptoms in type 1 and type 2 diabetes: differential associations with depressive symptom clusters

Herder C., Zhu A., Schmitt A. et al.

Proceedings of the National Academy of Sciences, 2025
Acyl-CoA-binding protein as a driver of pathological aging

Montégut L., Lambertucci F., Moledo-Nodar L. et al.

Translational Vision Science & Technology, 2025
Exploring the Mechanisms Linking Depression and Glaucoma: A Cohort Study of UK Biobank

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RMD Open, 2025
Molecular insights into the relationship between sustained CRP elevation and endothelial dysfunction in axial spondyloarthritis

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Brain, Behavior, & Immunity - Health, 2025
Bidirectional Mendelian randomization analysis of inflammatory factors and sleep related traits

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Cancer Biology & Medicine, 2025
High-precision immune-related plasma proteomics profiling predicts response to immunotherapy in patients with triple-negative breast cancer

Xiao Y., Zhang H., Xiao Y. et al.

Alzheimer's Research & Therapy, 2025
Low-dose interleukin-2 in patients with mild to moderate Alzheimer’s disease: a randomized clinical trial

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Cardiovascular Diabetology, 2025
Single nuclei RNA-sequencing unveils alveolar macrophages as drivers of endothelial damage in obese HFpEF-related pulmonary hypertension

Gorica E., Spezzini J., Papadopoulou I. et al.

Andrology, 2025
Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Ivell R., Tulumcu B., Alhujaili W. et al.

Nature Human Behaviour, 2025
Machine learning-assisted optimization of dietary intervention against dementia risk

Chen S., Chen H., You J. et al.

World Journal of Otorhinolaryngology - Head and Neck Surgery, 2025
Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

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Journal of Allergy and Clinical Immunology, 2025
Analysis of airway inflammation demonstrates a mechanism for T2-biologic failure in asthma

McDowell P., Azim A., Busby J. et al.

Cell Reports, 2025
Maternal obesity impairs fetal brown adipogenesis by attenuating fetal FGF21 signaling

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Scientific Reports, 2025
Genetic prediction of immune cells, inflammatory proteins, and metabolite-mediated association between gut microbiota and COPD: a Mendelian randomization study

Chen G., Jin Y., Chu C. et al.

Scientific Reports, 2025
Childhood obesity and insulin resistance is correlated with gut microbiome serum protein: an integrated metagenomic and proteomic analysis

Liu L., Li M., Qin Y. et al.

Vaccine, 2025
AS01-adjuvanted vaccine alters baseline correlates of T cell response to varicella zoster virus in older adults

Chan C., Ooi J., Koh C. et al.

npj Precision Oncology, 2025
The responses of HNSCC patients to immunotherapy are shown by two novel co-expression patterns

Daher-Ghanem N., Sharon S., Tao D. et al.

Scientific Reports, 2025
Proteomic risk scores for predicting common diseases using linear and neural network models in the UK biobank

Smith A., Elliott P., Mayr M. et al.