Markers of immune dysregulation in pediatric patients with severe bronchiolitis
Journal of Human Immunity, 2025
Hickey K., Gruber C., Buta-Panov S., Lee J., Stoffels G., Gangadharan S., Vicencio A., Bogunovic D.
| Disease area | Application area | Sample type | Products |
|---|---|---|---|
Respiratory Diseases Pediatrics | Pathophysiology Patient Stratification | Plasma |  Olink Target 96 |
Abstract
Children with bronchiolitis exhibit a unique immunophenotype. We identify a significant difference in plasmacytoid dendritic cells and eosinophils in hospitalized patients as compared to controls, as well as cytokines involved in airway inflammation that are significantly different in hospitalized patients as compared to controls.