Olink

Olink®
Part of Thermo Fisher Scientific

Olink software solutions

Access the latest versions and release notes of Olink software solutions.

General Terms and Conditions and End User License Agreement

By downloading or using the software you confirm and accept that Olink’s General Terms and Conditions and Olink’s End User License Agreement apply to any use of the Software and any data generated through use of the Software in connection with analysis of Olink Kits. Analysis, or End User License Agreement relay to third parties, of any intermediate data generated during analysis, including but not limited to BCL- and FASTQ-files, is not permitted without Olink’s prior written approval.

BY DOWNLOADING, USING OR SHARING THE SOFTWARE YOU ACCEPT THAT THE SOFTWARE IS PROVIDED “AS IS” AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL OLINK BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

Use of these software solutions requires purchase of a license from Olink Proteomics.

NPX™ Map software suite

The NPX Map software suite is a complete software platform that includes all the software and applications needed to transform NGS sequencing read-out into NPX for subsequent statistical analysis.

  • Regardless of which Olink product platform you use (Olink® Explore 384/3072, Olink® Explore HT or Olink® Reveal) you will use the same NPX Map software.
  • It comes in a desktop version for local installation and a CLI version for command-line operations.
  • The software has an embedded pre-processing solution that removes the requirement to use another software for the pre-processing step. However, this pre-processing solution is not supporting all types of NGS sequencing instruments.  For Illumina sequencing instruments you will need to use the ngs2counts software for the pre-processing step. For detailed information on what sequencers are supported by the NPX Map pre-processing solution, see the table below.
  • Access to old NPX Explore software products; If you need access to older software products fill the contact us form.

Panel Data Archive NPX Map

As new kit lots for Olink® Explore 384/3072, Olink® Explore HT and Olink® Reveal are released they are included in the Panel Data Archive. The latest version of the Panel Data Archive will always hold the complete archive of all available Olink Explore 384/3072, Olink Explore HT and Olink Reveal reagent kit lots. You can download and install the latest Panel Data Archive to NPX Map at any time without the need to update the NPX Map software version.

Release Notes Panel Data Archive NPX Map v 1.5.0
Panel Data Archive NPX Map v1.5.0

NPX Map software v1.3.0

Desktop version for local installation.
Release Notes NPX Map & NPX Map CLI v1.3.0
User manual NPX Map software v1.3.0

Instruction for installation of new NPX Map version

  1. Download & install the latest software version: NPX Map
  2. Unpack the ZIP file
  3. Double click the msi file
  4. Follow on screen instruction
  5. Follow instruction for downloading and installing the latest Panel Data Archive

MD5 (NPX_Map_Setup.msi) = 0b8d0dbdc6e92bd78de008292627810e

Instruction for installation of new Panel Data Archive version

  1. Download the latest Panel Data Archive: NPX Map Panel Data Archive v1.5.0
  2. Launch NPX Map
  3. Follow on screen instruction and import the Panel Data Archive

NPX Map CLI software

A command-line interface (cli) for NPX Map capable of performing normalization, quality control (QC) and CV computations on NGS data and exporting the results on several supported formats.

Release Notes NPX Map & NPX Map CLI v1.3.0
Technical information NPX ™ Map CLI  software v1.3.0

Instruction for installation of new NPX™ Map CLI and Panel Data Archive version

  1. Download & install the latest software version: NPX Map CLI 1.3.0
  2. Unpack the ZIP file
  3. Open the README.md file and follow the installation instructions

ngs2counts v6.2.0–pre-processing for Illumina instrument read-out

Release Notes ngs2counts v6.2.0
NPX™_Map_Preprocessing _v6.2.0 technical information

The Olink Explore pre-processing software package, ngs2counts v6.2.0 (for Illumina instrument read-out) comes with two installation alternatives:

  • Full installation which includes ngs2counts and the companion software Explore listener which detects when sequencing is complete and starts ngs2counts automatically.
  • Installation of ngs2counts only, suitable for use with an already existing data pipeline.

The Explore pre-processing software package will include both installation alternatives

  1. Download the latest software package: ngs2counts v6.2.0 (uploaded November 20, 2025)
  2. Unpack the ZIP folder
  3. Open the Technical Information and follow the installation instructions

NPX Signature

Olink Signature System Software

  • Obtain the software installer(.zip file)
  • Extract the zip file
  • Copy the .pak file to a USB drive
  • Power down the Q100, wait 30 seconds, then power Q100 on
  • Insert the USB drive into the USB port on the front of Olink Signature Q100
  • On the instrument, go to the Settings screen, then tap UPGRADE

Download ZIP v2.0 (Uploaded July 02, 2023)

Release notes v2.0

Signature Q100 Firmware upgrade

NPX Signature Software

The NPX Signature software is a complete software platform that includes all the software and applications needed to transform qPCR read-out (Ct values) into NPX and pg/ml for subsequent statistical analysis.

The same NPX Signature software can be used regardless of which Olink product platform you use (Olink Target 96, Olink Target 48, Olink Flex or Olink Focus).

The NPX Signature software is available as a desktop application for local installation.

Target Panel Data Archive

As new kit lots for Olink® Target 96 and Olink® Target 48 are released they are included in the Target Panel Data Archive. The latest version of the Target Panel Data Archive will always hold the complete archive of all available Olink® Target 96 and Olink® Target 48 reagent lots. You can download and install the latest Target Panel Data Archive to NPX Signature software at any time without the need to update the NPX Signature software version.

Documentation:

Release notes Target Panel Data Archive 2025 November 27

NPX Signature Software v2.2

Desktop version for local installation.

Release Notes – Software v2..2

User Manual 

Instructions for installation of new NPX Signature software version:

  1. Uninstall existing NPX S v1.x, if installed.
  2. Download & install the latest software version: NPX Signature Software v2.2
  3. Double click the .msi file
  4. Follow on screen instruction
  5. Follow instruction for downloading and installing the latest Panel Data Archive (Target) or Panel Data File (Flex & Focus)

Olink Target: Please download the latest Panel Data Archive. This Archive includes all panel data files for Target 48 and 96. For details, see below.

Olink Flex: Please download the latest Panel Data File* from https://insight.olink.com/flex-files

Olink Focus: The panel data file* is customized and provided via e-mail. If you did not receive this please contact support@olink.com.

Instruction for installation of new Target Panel Data Archive version:

  1. Download the latest Panel Data Archive and the release notes
  2. Launch NPX Signature software
  • Select Manage panel data files
  • Select Upload panel data file
  • Select downloaded file and follow on screen instructions

*To use NPX Signature software version 2.2 the file format with the _NPXSv2 extension is required.

Fluidigm setup files for Target 96 panels

Fluidigm setup files for Target 48 panels

Please see the Olink Target 48 User manual for instructions on how to setup up your Fluidigm Biomark for running Olink panel protocol.