Actionable insights into drug mode of action
The precise mode of action (MOA) through which a drug achieves its clinical aims may not be completely understood in many cases. Knowledge regarding MOA can be important for evaluating safety and establishing a more comprehensive picture of drug pharmacodynamics, and this is becoming increasingly relevant in the move towards precision medicine. Proteomic analysis of samples from clinical trials is increasingly used to facilitate a better understanding of MOA for the drug being evaluated.
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Olink Insight
Enter your targets and let Olink Insight reveal the connections. Use a list of proteins, genes, or publications to understand their active pathways.
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Olink’s PEA technology facilitates a deeper understanding of how a drug impacts biological pathways, what factors differentiate responders from non-responders and the biological mechanisms linked to patient outcomes. This data can help provide a more comprehensive MoA characterization, strengthening subsequent regulatory submissions. The growing use of Olink for these applications in clinical trial samples underscores the value of PEA in advancing therapeutic insights and treatment strategies in modern drug development.
A flexible platform that accelerates your research
Olink’s scalable technology provides optimized solutions for every stage of the biomarker workflow, from high-throughput discovery through validation and clinical utility.
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Olink Explore HT
Measure 5,400+ proteins with proven specificity to gain an understanding of disease at the protein level.
Proteins
5,400+ With proven specificity
Sample
2 µL Plasma, serum & more
Olink Flex
Run individually tailored studies by combining up to 21 biomarkers from our extensive library with minimal sample volume.
Proteins
~200 Pre-validated assays
Sample
1 µL Plasma, serum & more
Olink Target 96
Target specific disease areas or key biological processes with multiplex immunoassay panels.
Proteins
1,100+ On 15 targeted panels
Sample
1 µL Plasma, serum & more
Olink Target 48
Extensively validated and carefully selected biomarkers for a comprehensive view of cytokine signaling and inflammatory processes.
Proteins
89 On 2 panels
Sample
1 µL Plasma, serum & more