Olink

Olink®
Part of Thermo Fisher Scientific

Overview
Target 48 Neurodegeneration panel

Overview

  • Proteins

    42 1 Panel

  • Samples

    40 per Kit

  • Sample volume

    1 µL per panel

  • Readout

    pg/mL Absolute units

  • Runs on

    Signature Q100

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Benefits
Absolute quantification

Compare across cohorts, time points, and studies, empowered by precise absolute quantification. Generate rich, robust data from just a few microlitres of plasma or cerebral spinal fluid, maximizing the value of each precious sample.

Olink Target 48 Neurodegeneration banner.

Monitor longitudinal changes

Comparisons across timepoints of sample collection within a study or clinical trial.

Olink Target 48 Neurodegeneration banner.

Identify distinct profiles across projects

Comparisons between neurodegenerative diseases, disease subtypes, stages, or treatments within the same institute.

Olink Target 48 Neurodegeneration banner.

Collaborate and compare across sites

Comparison of data generated by different laboratories, either within the same project or across separate studies.

Biomarker library
Empowering neurodegeneration researchers towards translational insights

Designed in partnership with field experts, biobanks, and publications to prioritize markers with translational potential, Target 48 Neurodegeneration panel covers mechanisms critical to interrogate disease progression and further understanding of leading neuro disorders such as Alzheimer’s, Parkinson’s, and multiple sclerosis.

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Contact us to discover more and order your kit.

Disease applications
Key markers

Quantify pTau217, Aβ40, Aβ42, NfL, GFAP, and more in a single, scalable assay—saving time, cost, and precious patient sample.

Download Target 48 Neurodegeneration Assay list

Alzheimer’s disease and other dementias

pTau217, Aß40, Aß42, GFAP, NFL, NPTX2, BACE1, MMP10 and more.

Multiple sclerosis

MOG, OMG, NGF, NFL, GFAP and more.

Parkinson’s disease

DDC, SNCAIP, SCG2, LRRK2, GLRX and more.

Biomarker coverage

Profound insights

Uncover disease-driving biology with biomarker content purposefully curated by global experts and biobank data, spanning synaptic proteins, neuroinflammation, clearance, and beyond.

Download Target 48 Neurodegeneration Assay list

Target 48 Neurodegeneration assay list.

Neurodegeneration

Aß40, Aß42, pTau217, NEFL, WWOX, MOG, OMG, BMP7, EIF2AK2.

Target 48 Neurodegeneration assay list.

Synaptic function

NPTXR, NPTX1, NPTX2, CLSTN3, GLRX, NLGN1, STX1B, SYT1.

Target 48 Neurodegeneration assay list.

Clearance

DDHA1, BACE1, ENO2, KLK8, TP53, SCG2.

Target 48 Neurodegeneration assay list.

Neuroinflammation

GFAP, AGER, HLA-DRA, MMP10.

Research solutions

Expand your coverage with inflammation biomarkers

Combine Olink Target 48 Neurodegeneration with Olink Target 48 Cytokine or Olink Flex to gain comprehensive insights into neurodegeneration and inflammation with a flexible, unified workflow and uncompromised performance.

Olink Target 48 Cytokine

Covering 45 key immune markers.

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Olink Flex

Allows for combining 5-30 key immune biomarkers into one panel.

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Customer stories

Trusted by leading scientists

The Target 48 Neurodegeneration is a critical tool that enables the detection and quantification of key and emerging neurodegenerative disease biomarkers from plasma and cerebrospinal fluid samples. By generating quantitative data, it ensures reproducible results across and within longitudinal studies, moving a step forward towards clinical utilization.

Charlotte Teunissen

Professor in neurochemistry, Department of Laboratory Medicine, Amsterdam University Medical Center

What really stood out for us in using the Target 48 Neurodegeneration panel was the ability to generate rich and meaningful insights from a single experimental procedure with a simple workflow. The breadth of biomarkers — including pTau217, which showed strong correlation with Simoa — gave us a comprehensive view of neurodegeneration together with other pathophysiological processes and strengthened our confidence in interpreting and predicting disease-related changes. It’s a valuable approach for advancing research in Alzheimer’s disease and related dementias.

Professor Christopher Chen

National University of Singapore

Combining the Olink Target 48 Neurodegeneration and Target 48 Cytokine panels allowed us to quantify 86 biomarkers relevant to neurodegeneration and the immune response. The unified workflow of these panels offers a practical, cost-effective way to generate highly reproducible pg/mL data, supporting our study of chronic inflammation and neurocognitive impairment risk in HIV patients receiving antiviral therapy.

Daniel Kaufman

Clinical researcher and physician, Chief of Division of Infectious Diseases at the Lausanne University Hospital

    Platform benefits
    Elevate your immunoassay experience

    Beyond the Olink panel lies a wide range of free tools for study design, statistical analysis, data visualization and quality control. There’s also continuous support from our data science experts and customer service teams. We’re proud to be active partners to thousands of researchers, from small lab teams to major institutions and consortia.

    Streamlined workflow

    Focus your time and effort on your research instead of washing steps and hands-on instrument handling. Use NPX™ Signature for QC and to generate analysis reports.

    Documents
    Documents

    Below you will find a few documents related to this product. For the complete documentation including SDS, user manuals, technical notes and more, visit the documents section.

    DocumentsTypeFile
    Olink® Target 48 Neurodegeneration
    Validation data result
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    Olink® Target 48 Neurodegeneration
    Assay list
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    Target 48 Neurodegeneration - Clarity in complexity
    Flyer
    Download PDF
    Olink® Target 48 Neurodegeneration Brochure
    Brochure
    Download PDF

    Ready to take the next step?

    Contact us to discover more and order your kit.

    For Research Use Only. Not for use in diagnostic procedures.