Alimentary Pharmacology & Therapeutics, 2023
Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease

Ungaro R., Hu L., Ji J. et al.

Nature Communications, 2023
Interpreting biologically informed neural networks for enhanced proteomic biomarker discovery and pathway analysis

Hartman E., Scott A., Karlsson C. et al.

Thrombosis Research, 2023
Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease

Baidildinova G., Pallares Robles A., ten Cate V. et al.

Journal of the American Heart Association, 2023
Causal Effects of YKL‐40 on Ischemic Stroke and Its Subtypes: A 2‐Sample Mendelian Randomization Study

Xu Q., Sun L., Wang Y. et al.

Cell Reports Medicine, 2023
Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses

Yuan S., Xu F., Li X. et al.

Vascular Pharmacology, 2023
Circulating soluble IL-6 receptor associates with plaque inflammation but not with atherosclerosis severity and cardiovascular risk

Edsfeldt A., Gonçalves I., Vigren I. et al.

Science Translational Medicine, 2023
A complement atlas identifies interleukin-6–dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Van Damme K., Hoste L., Declercq J. et al.

Arthritis & Rheumatology, 2023
Elevation of IL‐17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders

Brodeur K., Liu M., Ibanez D. et al.

Journal for ImmunoTherapy of Cancer, 2023
Antitumor immunity as the basis for durable disease-free treatment-free survival in patients with metastatic urothelial cancer

Anker J., Pal S., Kim-Schulze S. et al.

Liver International, 2023
Binge drinking episode causes acute, specific alterations in systemic and hepatic inflammation‐related markers

Stankevic E., Israelsen M., Juel H. et al.

Journal of Endocrinological Investigation, 2023
Serum biomarkers related to frailty predict negative outcomes in older adults with hip fracture

Cedeno-Veloz B., Lozano-Vicario L., Rodríguez-García A. et al.

Nature Communications, 2023
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Brown A., Fernandez-Tajes J., Hong M. et al.

Journal of Cancer Research and Clinical Oncology, 2023
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study

Pham T., Nimptsch K., Papadimitriou N. et al.

Aging Cell, 2023
Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort

Chen J., Doyle M., Fang Y. et al.

Antioxidants, 2023
Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents

Ullah A., Stankevic E., Holm L. et al.

Journal of Cerebral Blood Flow & Metabolism, 2023
A cluster of blood-based protein biomarkers associated with decreased cerebral blood flow relates to future cardiovascular events in patients with cardiovascular disease

Overmars L., Kuipers S., van Es B. et al.

iScience, 2023
Transcriptomic and proteomic assessment of tocilizumab response in a randomized controlled trial of patients hospitalized with COVID-19

Shivram H., Hackney J., Rosenberger C. et al.

Nature Immunology, 2023
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Zhao J., Stacey D., Eriksson N. et al.

eClinicalMedicine, 2023
Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory mantle cell lymphoma (CITADEL-205): a phase 2 study

Zinzani P., Trněný M., Ribrag V. et al.

Nature Genetics, 2023
Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis

Zhou S., Sosina O., Bovijn J. et al.